DK324286A - 1-substituerede oxindol-3-carboxamider og deres anvendelse som antiinflammatoriske og analgetiske midler - Google Patents
1-substituerede oxindol-3-carboxamider og deres anvendelse som antiinflammatoriske og analgetiske midler Download PDFInfo
- Publication number
- DK324286A DK324286A DK324286A DK324286A DK324286A DK 324286 A DK324286 A DK 324286A DK 324286 A DK324286 A DK 324286A DK 324286 A DK324286 A DK 324286A DK 324286 A DK324286 A DK 324286A
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- carboxamides
- inflammatory
- analgetic agents
- oxindol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75320085A | 1985-07-09 | 1985-07-09 | |
| US82129686A | 1986-01-22 | 1986-01-22 | |
| US06/825,017 US4678802A (en) | 1985-07-09 | 1986-01-31 | 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK324286D0 DK324286D0 (da) | 1986-07-08 |
| DK324286A true DK324286A (da) | 1987-01-10 |
Family
ID=27419443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK324286A DK324286A (da) | 1985-07-09 | 1986-07-08 | 1-substituerede oxindol-3-carboxamider og deres anvendelse som antiinflammatoriske og analgetiske midler |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0208510B1 (da) |
| JP (1) | JPH0610193B2 (da) |
| CN (1) | CN86105309A (da) |
| AT (1) | ATE67185T1 (da) |
| AU (1) | AU566065B2 (da) |
| CA (1) | CA1286663C (da) |
| DE (1) | DE3681358D1 (da) |
| DK (1) | DK324286A (da) |
| ES (2) | ES2001855A6 (da) |
| FI (1) | FI862882A7 (da) |
| GR (1) | GR861760B (da) |
| HU (2) | HUT41386A (da) |
| IE (1) | IE58566B1 (da) |
| IL (1) | IL79356A (da) |
| NO (1) | NO862750L (da) |
| NZ (1) | NZ216788A (da) |
| PH (1) | PH22641A (da) |
| PT (1) | PT82931B (da) |
| YU (2) | YU45346B (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| FR2655344B1 (fr) * | 1989-12-06 | 1992-04-03 | Sanofi Sa | Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant. |
| WO1991009598A1 (en) * | 1990-01-05 | 1991-07-11 | Pfizer Inc. | Azaoxindole derivatives |
| FR2677356B1 (fr) * | 1991-06-05 | 1995-03-17 | Sanofi Sa | Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant. |
| JPH08288983A (ja) * | 1995-04-17 | 1996-11-01 | Tokyo Tsuuki:Kk | リンガ回路 |
| US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
| US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
| US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
| US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
| US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
| US6355648B1 (en) | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
| US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
| US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
| US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
| US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
| US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
| US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
| US6319912B1 (en) | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
| US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
| US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
| UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| US6900335B2 (en) | 2000-07-19 | 2005-05-31 | Ube Industries, Ltd. | Process for producing 5-fluorooxindole and for producing intermediates therefor |
| WO2002070478A1 (en) | 2001-03-06 | 2002-09-12 | Astrazeneca Ab | Indolone derivatives having vascular-damaging activity |
| JP4770826B2 (ja) * | 2007-11-22 | 2011-09-14 | 大日本印刷株式会社 | ２−オキシインドール誘導体の製造法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3749731A (en) | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US3882236A (en) | 1973-12-26 | 1975-05-06 | Lilly Co Eli | Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
-
1986
- 1986-07-02 DE DE8686305144T patent/DE3681358D1/de not_active Expired - Lifetime
- 1986-07-02 AT AT86305144T patent/ATE67185T1/de not_active IP Right Cessation
- 1986-07-02 EP EP86305144A patent/EP0208510B1/en not_active Expired - Lifetime
- 1986-07-07 GR GR861760A patent/GR861760B/el unknown
- 1986-07-07 CA CA000513184A patent/CA1286663C/en not_active Expired - Lifetime
- 1986-07-07 PT PT82931A patent/PT82931B/pt not_active IP Right Cessation
- 1986-07-08 AU AU59847/86A patent/AU566065B2/en not_active Ceased
- 1986-07-08 IL IL79356A patent/IL79356A/xx not_active IP Right Cessation
- 1986-07-08 IE IE183386A patent/IE58566B1/en not_active IP Right Cessation
- 1986-07-08 FI FI862882A patent/FI862882A7/fi not_active Application Discontinuation
- 1986-07-08 ES ES8600191A patent/ES2001855A6/es not_active Expired
- 1986-07-08 HU HU862844A patent/HUT41386A/hu not_active IP Right Cessation
- 1986-07-08 JP JP61160675A patent/JPH0610193B2/ja not_active Expired - Lifetime
- 1986-07-08 DK DK324286A patent/DK324286A/da not_active Application Discontinuation
- 1986-07-08 HU HU862844D patent/HU198015A/hu not_active IP Right Cessation
- 1986-07-08 YU YU1203/86A patent/YU45346B/xx unknown
- 1986-07-08 NO NO862750A patent/NO862750L/no unknown
- 1986-07-08 NZ NZ216788A patent/NZ216788A/xx unknown
- 1986-07-08 PH PH33993A patent/PH22641A/en unknown
- 1986-07-09 CN CN198686105309A patent/CN86105309A/zh active Pending
-
1987
- 1987-06-18 YU YU01144/87A patent/YU114487A/xx unknown
- 1987-12-15 ES ES8703589A patent/ES2009227A6/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO862750L (no) | 1987-01-12 |
| IL79356A (en) | 1990-03-19 |
| IE58566B1 (en) | 1993-10-06 |
| EP0208510A3 (en) | 1988-03-02 |
| AU566065B2 (en) | 1987-10-08 |
| PT82931A (en) | 1986-08-01 |
| PH22641A (en) | 1988-10-28 |
| FI862882L (fi) | 1987-01-10 |
| DK324286D0 (da) | 1986-07-08 |
| IL79356A0 (en) | 1986-10-31 |
| YU120386A (en) | 1988-02-29 |
| EP0208510A2 (en) | 1987-01-14 |
| NZ216788A (en) | 1988-10-28 |
| PT82931B (pt) | 1989-01-30 |
| AU5984786A (en) | 1987-04-09 |
| IE861833L (en) | 1987-01-09 |
| CA1286663C (en) | 1991-07-23 |
| CN86105309A (zh) | 1987-01-14 |
| GR861760B (en) | 1986-11-10 |
| YU114487A (en) | 1988-02-29 |
| HUT41386A (en) | 1987-04-28 |
| DE3681358D1 (de) | 1991-10-17 |
| FI862882A7 (fi) | 1987-01-10 |
| JPS6226269A (ja) | 1987-02-04 |
| FI862882A0 (fi) | 1986-07-08 |
| NO862750D0 (no) | 1986-07-08 |
| EP0208510B1 (en) | 1991-09-11 |
| ES2001855A6 (es) | 1988-07-01 |
| ES2009227A6 (es) | 1989-09-16 |
| YU45346B (en) | 1992-05-28 |
| JPH0610193B2 (ja) | 1994-02-09 |
| ATE67185T1 (de) | 1991-09-15 |
| HU198015A (en) | 1989-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |