DK324387A - Aza-bicycliske forbindelser - Google Patents

Aza-bicycliske forbindelser

Info

Publication number
DK324387A
DK324387A DK324387A DK324387A DK324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A
Authority
DK
Denmark
Prior art keywords
aza
bicyclic
relations
bicyclic relations
Prior art date
Application number
DK324387A
Other languages
Danish (da)
English (en)
Other versions
DK324387D0 (da
Inventor
Michael Stewart Hadley
Barry Sidney Orlek
Howard Elliott Rosenberg
Harry John Wadsworth
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK324387D0 publication Critical patent/DK324387D0/da
Publication of DK324387A publication Critical patent/DK324387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK324387A 1986-06-27 1987-06-25 Aza-bicycliske forbindelser DK324387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868615785A GB8615785D0 (en) 1986-06-27 1986-06-27 Compounds

Publications (2)

Publication Number Publication Date
DK324387D0 DK324387D0 (da) 1987-06-25
DK324387A true DK324387A (da) 1987-12-28

Family

ID=10600224

Family Applications (1)

Application Number Title Priority Date Filing Date
DK324387A DK324387A (da) 1986-06-27 1987-06-25 Aza-bicycliske forbindelser

Country Status (9)

Country Link
US (1) US4870081A (fr)
EP (1) EP0257741A3 (fr)
JP (1) JPS6339879A (fr)
AU (1) AU599990B2 (fr)
DK (1) DK324387A (fr)
GB (1) GB8615785D0 (fr)
NZ (1) NZ220840A (fr)
PT (1) PT85173B (fr)
ZA (1) ZA874626B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287356B1 (fr) * 1987-04-15 1996-01-24 Beecham Group Plc Dérivés azabicycliques substitués en tête de pont
PT90266B (pt) * 1988-04-15 1994-07-29 Beecham Group Plc Processo para a preparacao de compostos azabiciclicos
EP0363085A3 (fr) 1988-10-03 1991-03-27 Beecham Group Plc Composés chimiques
CA2000041A1 (fr) * 1988-10-13 1990-04-13 Barry S. Orlek Composes
SG48315A1 (en) * 1989-04-13 1998-04-17 Beecham Group Plc Novel compounds
GB8911080D0 (en) * 1989-05-15 1989-06-28 Merck Sharp & Dohme Chemical process
YU84791A (sh) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
WO1992003435A1 (fr) * 1990-08-24 1992-03-05 Beecham Group Plc Composes azabicyliques, procede et intermediaires servant dans leur preparation et compositions pharmaceutiques contenant ces composes
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
CA2093823A1 (fr) * 1990-10-12 1992-04-13 Steven M. Bromidge Derives de 1,2,5,6-tetrahydropyridine-oxime
HU209451B (en) * 1990-11-05 1994-06-28 Gyogyszerkutato Intezet Process for the production of 1-azabicyclo-alkan -derivatives and pharmaceutical preparations containing the same
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
US5468875A (en) * 1994-12-22 1995-11-21 American Home Products Corporation 1-azabicycloheptane derivatives
US5668144A (en) * 1995-11-08 1997-09-16 American Home Products Corporation 1-azabicyclopheptane derivatives
US5773458A (en) * 1996-10-30 1998-06-30 American Home Products Corporation 1-azabicycloheptane derivatives
US6875774B2 (en) * 2002-08-06 2005-04-05 The University Of North Carolina Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (fr) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
EP2068872A1 (fr) 2006-09-08 2009-06-17 Braincells, Inc. Combinaisons contenant un dérivé de 4-acylaminopyridine
WO2012033956A1 (fr) 2010-09-08 2012-03-15 Mithridion, Inc. Composés et compositions améliorant la cognition, méthodes de préparation et méthodes de traitement

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
DE1470084A1 (de) * 1964-08-19 1969-05-29 Merck Ag E Verfahren zur Herstellung von substituierten Piperidin-derivaten
US3501471A (en) * 1966-09-21 1970-03-17 American Cyanamid Co Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
IE56226B1 (en) * 1982-04-14 1991-05-22 Beecham Group Plc Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them
FR2526433B1 (fr) * 1982-05-04 1985-10-18 Pharmuka Lab Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant
GB8518236D0 (en) * 1985-07-19 1985-08-29 Beecham Group Plc Compounds
DE3687980T2 (de) * 1986-01-07 1993-06-17 Beecham Group Plc Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen.
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
SE461171C (sv) * 1988-05-25 1992-08-17 Valmet Paper Machinery Inc Press med laangt nyp foer pappers- eller kartongmaskiner

Also Published As

Publication number Publication date
EP0257741A2 (fr) 1988-03-02
GB8615785D0 (en) 1986-08-06
US4870081A (en) 1989-09-26
ZA874626B (en) 1988-08-31
PT85173A (en) 1987-07-01
PT85173B (pt) 1990-03-30
NZ220840A (en) 1990-08-28
JPS6339879A (ja) 1988-02-20
AU599990B2 (en) 1990-08-02
DK324387D0 (da) 1987-06-25
EP0257741A3 (fr) 1989-09-06
AU7469487A (en) 1988-01-07

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment