DK3247699T3 - Proces til produktion of 2-[4-(cyclopropancarbonyl)phenyl]-2-methyl-propannitril - Google Patents

Proces til produktion of 2-[4-(cyclopropancarbonyl)phenyl]-2-methyl-propannitril Download PDF

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Publication number
DK3247699T3
DK3247699T3 DK16701157.6T DK16701157T DK3247699T3 DK 3247699 T3 DK3247699 T3 DK 3247699T3 DK 16701157 T DK16701157 T DK 16701157T DK 3247699 T3 DK3247699 T3 DK 3247699T3
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DK
Denmark
Prior art keywords
propannitril
cyclopropancarbonyl
phenyl
methyl
production
Prior art date
Application number
DK16701157.6T
Other languages
English (en)
Inventor
Hermut Wehlan
Kai Rossen
Alexander Schaefer
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK3247699T3 publication Critical patent/DK3247699T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK16701157.6T 2015-01-22 2016-01-21 Proces til produktion of 2-[4-(cyclopropancarbonyl)phenyl]-2-methyl-propannitril DK3247699T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152101 2015-01-22
PCT/EP2016/051223 WO2016116555A1 (en) 2015-01-22 2016-01-21 Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile

Publications (1)

Publication Number Publication Date
DK3247699T3 true DK3247699T3 (da) 2019-08-12

Family

ID=52394944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16701157.6T DK3247699T3 (da) 2015-01-22 2016-01-21 Proces til produktion of 2-[4-(cyclopropancarbonyl)phenyl]-2-methyl-propannitril

Country Status (12)

Country Link
US (1) US10336698B2 (da)
EP (1) EP3247699B1 (da)
CN (1) CN107428678B (da)
CA (1) CA2974449C (da)
DK (1) DK3247699T3 (da)
ES (1) ES2738630T3 (da)
HR (1) HRP20191146T1 (da)
HU (1) HUE044642T2 (da)
PL (1) PL3247699T3 (da)
PT (1) PT3247699T (da)
RS (1) RS58961B1 (da)
WO (1) WO2016116555A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10696633B2 (en) * 2015-10-22 2020-06-30 Sanofi-Aventis Deutschland Gmbh Process for the preparation of fexofenadine and of intermediates used therein
WO2019232294A1 (en) * 2018-06-01 2019-12-05 Cornell University Metal-chelating compositions and their use in methods of removing or inhibiting barium scale

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
JPS60130561A (ja) 1983-12-16 1985-07-12 Torii Yakuhin Kk アミジン誘導体およびそれを含む強心剤
DE3839170A1 (de) 1988-11-19 1990-05-31 Bayer Ag Cyclopropyl-substituierte azolylmethylcarbinole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA2166059C (en) 1993-06-25 2005-08-16 Richard Carl Krauss Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
US5420322A (en) 1994-08-31 1995-05-30 Mine Safety Appliances Company Preparation of alkali-metal hexamethydisilazanes
US6303782B1 (en) * 1999-04-20 2001-10-16 Pfizer Inc Process for preparing benzylnitriles
GB0018691D0 (en) 2000-07-28 2000-09-20 Rolabo Sl Process
US20050222154A1 (en) 2004-04-05 2005-10-06 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
WO2005110996A1 (en) 2004-05-18 2005-11-24 F.Hoffmann-La Roche Ag Novel cis-imidazolines
GT200600179A (es) 2005-04-29 2006-11-22 Proceso para preparar oxindoles y tio-oxindoles 3,3-disustituidos
DE102005045132A1 (de) 2005-09-22 2007-03-29 Archimica Gmbh Verfahren zur Herstellung von 2-Arylcarbonylverbindungen, 2-Arylestern und 2-Arylnitrilen sowie ihrer heteroaromatischen Analoga
GB0705656D0 (en) 2007-03-23 2007-05-02 Addex Pharmaceuticals Sa Novel compounds E1
WO2009001127A1 (en) 2007-06-26 2008-12-31 Astrazeneca Ab Cyanocyclopropylcarboxamides as cathepsin inhibitors
EP2601190B1 (en) 2010-08-05 2018-07-04 Zoetis Services LLC Isoxazoline derivatives as antiparasitic agents
HK1197060A1 (en) 2011-08-17 2015-01-02 F. Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase
RU2015122218A (ru) 2012-11-30 2017-01-10 Ф. Хоффманн-Ля Рош Аг Ингибиторы тирозинкиназы брутона

Also Published As

Publication number Publication date
CA2974449C (en) 2023-08-29
EP3247699B1 (en) 2019-05-15
US10336698B2 (en) 2019-07-02
ES2738630T3 (es) 2020-01-24
HRP20191146T1 (hr) 2019-10-04
HUE044642T2 (hu) 2019-11-28
CN107428678A (zh) 2017-12-01
CN107428678B (zh) 2021-01-01
US20170369440A1 (en) 2017-12-28
PL3247699T3 (pl) 2019-11-29
WO2016116555A1 (en) 2016-07-28
PT3247699T (pt) 2019-08-06
RS58961B1 (sr) 2019-08-30
CA2974449A1 (en) 2016-07-28
EP3247699A1 (en) 2017-11-29

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