DK327589A - Fremstilling af dyrelysozym c fra udskillelse ved pichia pastoris samt middel derfor - Google Patents

Fremstilling af dyrelysozym c fra udskillelse ved pichia pastoris samt middel derfor Download PDF

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Publication number
DK327589A
DK327589A DK327589A DK327589A DK327589A DK 327589 A DK327589 A DK 327589A DK 327589 A DK327589 A DK 327589A DK 327589 A DK327589 A DK 327589A DK 327589 A DK327589 A DK 327589A
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Denmark
Prior art keywords
lyzozym
animal
substances
separation
preparation
Prior art date
Application number
DK327589A
Other languages
Danish (da)
English (en)
Other versions
DK327589D0 (da
Inventor
Mary Ellen Digan
Steven Bradley Ellis
Mark Edward Williams
Michael Miller Harpold
Stephen Vernon Lair
Gregory Patrick Thill
Robert Steven Siegel
Original Assignee
Salk Inst Biotech Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Salk Inst Biotech Ind filed Critical Salk Inst Biotech Ind
Publication of DK327589D0 publication Critical patent/DK327589D0/da
Publication of DK327589A publication Critical patent/DK327589A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462Lysozyme (3.2.1.17)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
DK327589A 1987-11-02 1989-06-30 Fremstilling af dyrelysozym c fra udskillelse ved pichia pastoris samt middel derfor DK327589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11594087A 1987-11-02 1987-11-02
PCT/US1988/003907 WO1989004320A1 (fr) 1987-11-02 1988-11-02 PRODUCTION DE LYSOZYME c DE TYPE ANIMAL PAR SECRETION DE CELLULES DE PICHIA PASTORIS ET COMPOSITION PREVUE A CET EFFET

Publications (2)

Publication Number Publication Date
DK327589D0 DK327589D0 (da) 1989-06-30
DK327589A true DK327589A (da) 1989-06-30

Family

ID=22364276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK327589A DK327589A (da) 1987-11-02 1989-06-30 Fremstilling af dyrelysozym c fra udskillelse ved pichia pastoris samt middel derfor

Country Status (8)

Country Link
EP (1) EP0343231A4 (fr)
JP (1) JPH02501976A (fr)
KR (1) KR890701606A (fr)
AU (1) AU2825489A (fr)
CA (1) CA1340063C (fr)
DK (1) DK327589A (fr)
FI (1) FI893207A7 (fr)
WO (1) WO1989004320A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4332589A (en) * 1988-09-26 1990-04-18 Salk Institute Biotechnology/Industrial Associates, Inc., The Mixed feed recombinant yeast fermentation
US5122465A (en) * 1989-06-12 1992-06-16 Phillips Petroleum Company Strains of pichia pastoris created by interlocus recombination
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
JPH06506117A (ja) * 1991-04-01 1994-07-14 メルク エンド カンパニー インコーポレーテッド ピキア(Pichia)蛋白質分解活性に影響する遺伝子およびその使用
US5422108A (en) * 1991-09-19 1995-06-06 Smart Plants International Inc. Protection of plants against plant pathogens
US5850025A (en) * 1991-09-19 1998-12-15 Sibia Neurosciences, Inc. Protection of plants against plant pathogens
CN109810963B (zh) * 2017-11-22 2021-09-28 上海复华兴生物技术有限公司 一种新的牛肠源溶菌酶蛋白的dna序列及其生产工艺和应用
CN110903991A (zh) * 2019-11-13 2020-03-24 浙江新银象生物工程有限公司 一种含高拷贝数人源溶菌酶基因的重组毕赤酵母工程菌及其应用
CN112029783B (zh) * 2020-09-15 2022-05-27 西南民族大学 利用毕赤酵母异源表达反刍动物胃溶菌酶的方法
CN115873733B (zh) * 2022-07-20 2024-06-25 青岛蔚蓝生物集团有限公司 一种高产溶菌酶的毕赤酵母菌株及其应用

Also Published As

Publication number Publication date
FI893207L (fi) 1989-06-30
KR890701606A (ko) 1989-12-21
FI893207A0 (fi) 1989-06-30
DK327589D0 (da) 1989-06-30
EP0343231A4 (en) 1990-09-05
WO1989004320A1 (fr) 1989-05-18
JPH02501976A (ja) 1990-07-05
CA1340063C (fr) 1998-09-29
EP0343231A1 (fr) 1989-11-29
FI893207A7 (fi) 1989-06-30
AU2825489A (en) 1989-06-01

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