DK328478A - Fremgangsmaade til fremstilling af pyrrolo (2,1-b) (3) benzazepiner - Google Patents

Fremgangsmaade til fremstilling af pyrrolo (2,1-b) (3) benzazepiner

Info

Publication number
DK328478A
DK328478A DK328478A DK328478A DK328478A DK 328478 A DK328478 A DK 328478A DK 328478 A DK328478 A DK 328478A DK 328478 A DK328478 A DK 328478A DK 328478 A DK328478 A DK 328478A
Authority
DK
Denmark
Prior art keywords
benzazepines
pyrrolo
procedure
preparation
Prior art date
Application number
DK328478A
Other languages
English (en)
Inventor
J G Atkinson
C S Rooney
P C Belanger
D C Remy
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK328478A publication Critical patent/DK328478A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK328478A 1977-07-28 1978-07-24 Fremgangsmaade til fremstilling af pyrrolo (2,1-b) (3) benzazepiner DK328478A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/819,739 US4148903A (en) 1977-07-28 1977-07-28 Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines

Publications (1)

Publication Number Publication Date
DK328478A true DK328478A (da) 1979-01-29

Family

ID=25228916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK328478A DK328478A (da) 1977-07-28 1978-07-24 Fremgangsmaade til fremstilling af pyrrolo (2,1-b) (3) benzazepiner

Country Status (7)

Country Link
US (1) US4148903A (da)
EP (1) EP0000716B1 (da)
JP (1) JPS5427597A (da)
DE (1) DE2862196D1 (da)
DK (1) DK328478A (da)
IE (1) IE47146B1 (da)
IT (1) IT1107463B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242349A (en) * 1979-10-01 1980-12-30 Merck & Co., Inc. Orexigenic use of pyrrolo[2,1-b][3]benzazepines
ATE124045T1 (de) * 1990-10-10 1995-07-15 Schering Corp Substituierte imidazobenzazepine und imidazopyridoazepine.
IL101851A (en) * 1991-06-13 1996-05-14 Janssen Pharmaceutica Nv 10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv 11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
ITRM20040178A1 (it) * 2004-04-07 2004-07-07 Sigma Tau Ind Farmaceuti Composti ad attivita' antipsicotica atipica.
BRPI0710085B8 (pt) 2006-03-31 2021-05-25 Vistakon Pharmaceutical Llc composições oftálmicas e seus kits
WO2025186833A1 (en) * 2024-03-07 2025-09-12 Council Of Scientific And Industrial Research Dihydrobenzo[b,e]pyrroloazepines hybrids and a process for the preparation thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA746508A (en) * 1966-11-15 D. Marcus Arnold Dibenzocycloheptenes
US3014911A (en) * 1958-09-29 1961-12-26 Merck & Co Inc Derivatives of dibenzo[a, e]cycloheptatriene
US3458522A (en) * 1967-05-17 1969-07-29 Sandoz Ag 4-piperidine substituted benzocycloheptaoxazoles and benzocycloheptathiazoles
US3988342A (en) * 1972-08-14 1976-10-26 Merck & Co., Inc. Piperidylidene derivatives of cyano-5H-dibenzo[a,d]cycloheptene
CA1092105A (en) * 1975-07-02 1980-12-23 Joshua Rokach Pyrrolo(2,1-b) (3)benzazepines
US4031222A (en) * 1975-12-22 1977-06-21 Merck & Co., Inc. Trifluoromethylthio (and sulfonyl) derivatives of cyproheptadine analogs
US4056536A (en) * 1976-06-29 1977-11-01 Merck & Co., Inc. Pyrrolo[2,1-b][3]benzazepines

Also Published As

Publication number Publication date
IT7850403A0 (it) 1978-07-20
EP0000716A2 (en) 1979-02-21
EP0000716A3 (en) 1979-05-16
IE47146B1 (en) 1983-12-28
IT1107463B (it) 1985-11-25
EP0000716B1 (en) 1983-03-09
DE2862196D1 (en) 1983-04-14
IE781517L (en) 1979-01-28
US4148903A (en) 1979-04-10
JPS5427597A (en) 1979-03-01

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment