DK328586A - Phenylethanolaminotetraliner og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem - Google Patents

Phenylethanolaminotetraliner og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem Download PDF

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Publication number
DK328586A
DK328586A DK328586A DK328586A DK328586A DK 328586 A DK328586 A DK 328586A DK 328586 A DK328586 A DK 328586A DK 328586 A DK328586 A DK 328586A DK 328586 A DK328586 A DK 328586A
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DK
Denmark
Prior art keywords
phenylethanolaminotetralines
procedures
preparing
pharmaceutical agents
agents containing
Prior art date
Application number
DK328586A
Other languages
English (en)
Other versions
DK328586D0 (da
DK167353B1 (da
Inventor
Roberto Cecchi
Robert Boigegrain
Alberto Bianchetti
Elena Poggesi
Tiziano Croci
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8510559A external-priority patent/FR2584712B1/fr
Priority claimed from FR8606626A external-priority patent/FR2598410B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK328586D0 publication Critical patent/DK328586D0/da
Publication of DK328586A publication Critical patent/DK328586A/da
Application granted granted Critical
Publication of DK167353B1 publication Critical patent/DK167353B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK328586A 1985-07-10 1986-07-10 Phenylethanolaminotetraliner og farmaceutisk acceptable salte deraf og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem DK167353B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8510559A FR2584712B1 (fr) 1985-07-10 1985-07-10 Phenylethanolamines a activite lipolytique, un procede pour leur preparation et compositions pharmaceutiques en contenant
FR8510559 1985-07-10
FR8606626A FR2598410B1 (fr) 1986-05-07 1986-05-07 Phenylethanolamines optiquement actives, un procede pour leur preparation et compositions pharmaceutiques en contenant
FR8606626 1986-05-07

Publications (3)

Publication Number Publication Date
DK328586D0 DK328586D0 (da) 1986-07-10
DK328586A true DK328586A (da) 1987-01-11
DK167353B1 DK167353B1 (da) 1993-10-18

Family

ID=26224609

Family Applications (1)

Application Number Title Priority Date Filing Date
DK328586A DK167353B1 (da) 1985-07-10 1986-07-10 Phenylethanolaminotetraliner og farmaceutisk acceptable salte deraf og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem

Country Status (18)

Country Link
US (1) US4707497A (da)
EP (1) EP0211721B1 (da)
JP (1) JPS6263549A (da)
KR (1) KR940007739B1 (da)
AR (1) AR241014A1 (da)
AT (1) ATE46900T1 (da)
AU (1) AU596976B2 (da)
CA (1) CA1260493A (da)
DE (1) DE3666036D1 (da)
DK (1) DK167353B1 (da)
ES (1) ES2002717A6 (da)
FI (1) FI85692C (da)
GR (1) GR861764B (da)
IE (1) IE59399B1 (da)
IL (1) IL79323A (da)
NO (1) NO165190C (da)
NZ (1) NZ216793A (da)
PT (1) PT82930B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623941A1 (de) * 1986-07-16 1988-01-28 Bayer Ag Substituierte amino-5,6,7,8-tetrahydronaphthyl-oxyessigsaeuren, verfahren zu deren herstellung sowie die verwendung als arzneimittel
US5153225A (en) * 1986-12-10 1992-10-06 Bayer Aktiengesellschaft Substituted basic 2-aminotetralin in pharmaceuticals
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
IT1199339B (it) * 1986-12-23 1988-12-30 Sigma Tau Ind Farmaceuti N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono
FR2619378B1 (fr) * 1987-08-12 1989-12-15 Midy Spa Procede pour la preparation de phenylethanolaminotetralines
US5198586A (en) * 1987-08-12 1993-03-30 Sanofi Process for the preparation of phenylethanolaminotetralins
FR2632637B1 (fr) * 1988-06-14 1990-10-12 Midy Spa Ethers de la 2-amino-7-hydroxytetraline
US5235103A (en) * 1987-08-12 1993-08-10 Sanofi Process for the preparation of phenylethanolaminotetralins
FR2619379B1 (fr) * 1987-08-12 1990-01-12 Midy Spa Procede pour la o-alkylation de n-(hydroxy) aralkyl-phenylethanolamines
EP0303546B1 (fr) * 1987-08-12 1994-12-28 Sanofi Procédé pour la O-alkylation de N-(hydroxy)aralkylphényléthanolamines
DE3872100T2 (de) * 1987-08-12 1993-01-28 Sanofi Elf Verfahren zur herstellung von phenylaethanolaminotetralinen.
FR2629453B1 (fr) * 1988-03-30 1990-10-05 Midy Spa Procede pour la preparation de phenylethanolaminotetralines
FR2632636B1 (fr) * 1988-06-14 1991-03-22 Midy Spa Procede pour la preparation de phenylethanolaminotetralines
FR2619718B1 (fr) * 1987-09-02 1991-07-12 Medibrevex Nouvelles formes galeniques de beta-2-mimetiques pour administration par voie per- et sublinguale
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
US5202466A (en) * 1988-06-14 1993-04-13 Sanofi 2-amino-7-hydroxytetraline ethers
FR2648042B1 (fr) * 1989-06-13 1994-06-10 Midy Spa Utilisation de phenylethanolaminotetralines pour la preparation de medicaments pour le traitement des affections oculaires
FR2643076B1 (fr) * 1989-02-14 1991-06-21 Midy Spa Carboxyalkyl-ethers de la 2-amino-7-hydroxytetraline
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
IT1230931B (it) * 1989-06-27 1991-11-08 Chiesi Farma Spa Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
FR2653765B1 (fr) * 1989-10-31 1993-08-06 Midy Spa Procede pour la preparation enantioselective de 2-aminotetralines.
FR2656607B1 (fr) * 1989-12-29 1994-03-11 Midy Spa Phenylethanolaminomethyltetralines.
IE65511B1 (en) * 1989-12-29 1995-11-01 Sanofi Sa New phenylethanolaminomethyltetralins
FR2669821A1 (fr) * 1990-12-04 1992-06-05 Sanofi Sa Utilisation de phenylethanolaminotetralines pour la preparation de medicaments destines au traitement de la depression.
EP0499755A1 (fr) * 1991-02-18 1992-08-26 MIDY S.p.A. Nouvelles phényléthanolaminotétralines, procédé pour leur préparation, intermédiaires dans ce procédé et compositions pharmaceutiques les contenant
GB9107827D0 (en) * 1991-04-12 1991-05-29 Fujisawa Pharmaceutical Co New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE69317399T2 (de) * 1993-01-29 1998-07-02 American Cyanamid Co Aminocycloalkanobenzodioxole als beta-3 selektive adrenergische Wirkstoffe
EP0627407A1 (fr) * 1993-05-28 1994-12-07 MIDY S.p.A. Acide (7S)-7-[(2R)-2(3-chlorophényl)-2-hydroxyéthylamino]-5,6,7,8-tétrahydronaphtalèn-2-yloxy acétique, ses sels pharmaceutiquement acceptables, à action agoniste bêta-3 adrénergique et compositions pharmaceutiques le contenant
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5491134A (en) * 1994-09-16 1996-02-13 Bristol-Myers Squibb Company Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
WO1997005091A1 (en) * 1995-07-26 1997-02-13 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients
US6197993B1 (en) 1996-07-02 2001-03-06 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives and a pharmaceutical composition comprising them as an active ingredient
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6075040A (en) * 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
EP0827746B1 (en) 1996-09-05 2002-04-03 Eli Lilly And Company Carbazole analogues as selective beta3 adrenergic agonists
FR2758723B1 (fr) * 1997-01-28 1999-04-23 Sanofi Sa Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
WO1999051564A1 (en) * 1998-04-06 1999-10-14 Fujisawa Pharmaceutical Co., Ltd. Propanolamine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK254975A (da) * 1974-06-12 1975-12-13 Takeda Chemical Industries Ltd Fremgangsmade til fremstilling af aminotetralolforbindelser
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
ATE6500T1 (de) * 1980-01-30 1984-03-15 American Hospital Supply Corporation 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3 4-tetrahydronaphthalin, seine salze, und verfahren zu dessen herstellung.

Also Published As

Publication number Publication date
PT82930A (fr) 1986-08-01
FI85692B (fi) 1992-02-14
JPS6263549A (ja) 1987-03-20
FI862907L (fi) 1987-01-11
NO165190B (no) 1990-10-01
NO862773L (no) 1987-01-12
IE59399B1 (en) 1994-02-23
AR241014A1 (es) 1991-04-30
US4707497A (en) 1987-11-17
AU5988986A (en) 1987-01-15
ES2002717A6 (es) 1992-04-16
NO862773D0 (no) 1986-07-09
IL79323A0 (en) 1986-10-31
ATE46900T1 (de) 1989-10-15
EP0211721A1 (fr) 1987-02-25
DK328586D0 (da) 1986-07-10
KR940007739B1 (ko) 1994-08-24
JP5071581B2 (da) 1993-10-07
IL79323A (en) 1990-03-19
DK167353B1 (da) 1993-10-18
EP0211721B1 (fr) 1989-10-04
CA1260493A (en) 1989-09-26
GR861764B (en) 1986-11-10
NZ216793A (en) 1990-05-28
FI85692C (fi) 1992-05-25
FI862907A0 (fi) 1986-07-10
IE861820L (en) 1987-01-10
AU596976B2 (en) 1990-05-24
NO165190C (no) 1991-01-09
AR241014A2 (es) 1991-04-30
PT82930B (pt) 1989-01-30
KR870001151A (ko) 1987-03-11
DE3666036D1 (en) 1989-11-09

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed