DK3302435T3 - Liposomladning - Google Patents

Liposomladning Download PDF

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Publication number
DK3302435T3
DK3302435T3 DK16800705.2T DK16800705T DK3302435T3 DK 3302435 T3 DK3302435 T3 DK 3302435T3 DK 16800705 T DK16800705 T DK 16800705T DK 3302435 T3 DK3302435 T3 DK 3302435T3
Authority
DK
Denmark
Prior art keywords
lipo
recharging
lipo recharging
Prior art date
Application number
DK16800705.2T
Other languages
English (en)
Inventor
Timothy D Heath
Lisa Ann Krugner-Higby
Amy Lautenbach
Original Assignee
Plumb Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plumb Pharmaceuticals Inc filed Critical Plumb Pharmaceuticals Inc
Application granted granted Critical
Publication of DK3302435T3 publication Critical patent/DK3302435T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • A61K9/1278Post-loading, e.g. by ion or pH gradient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47064-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16800705.2T 2015-05-26 2016-05-26 Liposomladning DK3302435T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562166223P 2015-05-26 2015-05-26
US201662291225P 2016-02-04 2016-02-04
PCT/US2016/034305 WO2016191547A1 (en) 2015-05-26 2016-05-26 Liposome loading

Publications (1)

Publication Number Publication Date
DK3302435T3 true DK3302435T3 (da) 2023-06-06

Family

ID=57393076

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16800705.2T DK3302435T3 (da) 2015-05-26 2016-05-26 Liposomladning

Country Status (4)

Country Link
US (4) US9931298B2 (da)
EP (2) EP4212148A1 (da)
DK (1) DK3302435T3 (da)
WO (1) WO2016191547A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016191547A1 (en) * 2015-05-26 2016-12-01 Comfort Care For Animals Llc Liposome loading
MX382522B (es) 2015-10-16 2025-03-13 Ipsen Biopharm Ltd Composiciones farmaceuticas estabilizantes de camptotecina.
CN110496103B (zh) * 2018-05-18 2022-05-10 上海维洱生物医药科技有限公司 一种多西他赛棕榈酸酯脂质体及其制备方法
JP7482487B2 (ja) * 2018-09-13 2024-05-14 タイワン リポソーム カンパニー リミテッド 鎮静薬を含む徐放性医薬組成物およびその使用
TWI767149B (zh) * 2018-10-17 2022-06-11 台灣微脂體股份有限公司 含有免疫調節劑的緩釋藥物組合物及其用途
EP4013390A1 (en) * 2019-08-12 2022-06-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Pharmaceutical compositions comprising a combination of opioid antagonists
AU2021413216A1 (en) * 2020-12-30 2023-07-20 BioCorRx Inc. Biodegradable implant including naltrexone and cholesterol
CN117088935A (zh) * 2022-05-20 2023-11-21 上海维洱生物医药科技有限公司 一种雷公藤甲素木蜡酸酯及其脂质体与制备方法
CN116211868B (zh) * 2023-03-04 2024-02-13 济南市中心医院 一种头孢克肟抗生素片剂及其制备方法
WO2025235614A1 (en) * 2024-05-08 2025-11-13 Plumb Pharmaceuticals, Inc. Liposome loading with polyanions

Family Cites Families (28)

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US3993754A (en) 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
US4086257A (en) 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
CH624011A5 (da) 1977-08-05 1981-07-15 Battelle Memorial Institute
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4522803A (en) 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4588578A (en) 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
US4935171A (en) 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation
EA200501285A1 (ru) 2003-02-11 2006-02-24 Неофарм, Инк. Способ получения липосомальных препаратов
CN100427064C (zh) * 2003-04-16 2008-10-22 沈阳药科大学 一种制备脂质体的新方法
CA2928387A1 (en) * 2004-05-03 2005-11-17 Merrimack Pharmaceuticals, Inc. Drug delivery liposomes containing anionic polyols or anionic sugars
US7465590B1 (en) 2005-06-30 2008-12-16 Nanometrics Incorporated Measurement of a sample using multiple models
WO2007049278A2 (en) * 2005-10-26 2007-05-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem A method for preparing liposomes and uses thereof
US8404650B2 (en) * 2005-10-28 2013-03-26 The Regents Of The University Of Colorado, A Body Corporate Methods of treating cancer with doxazolidine and prodrugs thereof
EP2004141A2 (en) * 2006-03-17 2008-12-24 Novosom AG An efficient method for loading amphoteric liposomes with nucleic acid active substances
JP5322476B2 (ja) * 2008-03-31 2013-10-23 テルモ株式会社 リポソームの製造装置およびリポソームの製造方法
EP2319519B1 (en) * 2008-08-01 2016-01-27 Kyowa Hakko Kirin Co., Ltd. Composition for inhibiting expression of target gene
WO2010074172A1 (ja) 2008-12-24 2010-07-01 株式会社バイオメッドコア リポソームの製造方法ならびにコレステロール溶解方法
FR2943669B1 (fr) * 2009-03-24 2011-05-06 Sanofi Aventis Derives de nicotinamide,leur preparation et leur application en therapeutique
JP5337722B2 (ja) 2010-01-07 2013-11-06 ヤマハ発動機株式会社 船舶用推進制御装置および船舶
EP2675918B1 (en) 2011-02-15 2017-11-08 Merrimack Pharmaceuticals, Inc. Compositions and methods for delivering nucleic acid to a cell
WO2012155048A1 (en) * 2011-05-11 2012-11-15 Wisconsin Alumni Research Foundation Liposome-encapsulated hydrogels for use in a drug delivery system
US20140079773A1 (en) * 2012-09-18 2014-03-20 Comfort Care For Animals Llc Encapsulating liposomes
EP4309657A3 (en) * 2013-02-01 2024-02-28 Celator Pharmaceuticals, Inc. Remote loading of sparingly water-soluble drugs into liposomes
WO2016191547A1 (en) * 2015-05-26 2016-12-01 Comfort Care For Animals Llc Liposome loading

Also Published As

Publication number Publication date
EP3302435B1 (en) 2023-03-08
US20160346205A1 (en) 2016-12-01
US11000478B2 (en) 2021-05-11
US20210361576A1 (en) 2021-11-25
WO2016191547A1 (en) 2016-12-01
US9931298B2 (en) 2018-04-03
US20250041223A1 (en) 2025-02-06
EP3302435A4 (en) 2018-12-26
US12059499B2 (en) 2024-08-13
HK1255538A1 (en) 2019-08-23
US20180200187A1 (en) 2018-07-19
CA3024951A1 (en) 2016-12-01
EP3302435A1 (en) 2018-04-11
EP4212148A1 (en) 2023-07-19

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