DK334383A - Fremgangsmaade til fremstilling af mannich-baser - Google Patents

Fremgangsmaade til fremstilling af mannich-baser Download PDF

Info

Publication number: DK334383A
Authority: DK; Denmark
Prior art keywords: manufacturing; mannich bases; ylmethylthio; ethylamino; ylmethyl
Prior art date: 1982-07-20

Application number

DK334383A

Other languages

English (en)

Other versions

DK334383D0 (da

Inventor

John Cooper

Michael Anthony Forth

Alan William Tremper

Kathleen Laura Wert

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-07-20

Filing date

1983-07-20

Publication date

1984-01-21

1983-07-20 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1983-07-20 Publication of DK334383D0 publication Critical patent/DK334383D0/da

1984-01-21 Publication of DK334383A publication Critical patent/DK334383A/da

Links

238000000034 method Methods 0.000 title abstract 2
RREANTFLPGEWEN-MBLPBCRHSA-N 7-[4-[[(3z)-3-[4-amino-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-yl]imino-5-fluoro-2-oxoindol-1-yl]methyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(\N=C/3C4=CC(F)=CC=C4N(CN4CCN(CC4)C=4C(=CC=5C(=O)C(C(O)=O)=CN(C=5C=4)C4CC4)F)C\3=O)=NC=2)N)=C1 RREANTFLPGEWEN-MBLPBCRHSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000000031 ethylamino group Chemical group [H]C([H])([H])C([H])([H])N([H])[*] 0.000 abstract 2
229940122957 Histamine H2 receptor antagonist Drugs 0.000 abstract 1
239000003485 histamine H2 receptor antagonist Substances 0.000 abstract 1
VGIVLIHKENZQHQ-UHFFFAOYSA-N n,n,n',n'-tetramethylmethanediamine Chemical compound CN(C)CN(C)C VGIVLIHKENZQHQ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK334383A 1982-07-20 1983-07-20 Fremgangsmaade til fremstilling af mannich-baser DK334383A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8220898		1982-07-20

Publications (2)

Publication Number	Publication Date
DK334383D0 DK334383D0 (da)	1983-07-20
DK334383A true DK334383A (da)	1984-01-21

Family

ID=10531771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK334383A DK334383A (da)	1982-07-20	1983-07-20	Fremgangsmaade til fremstilling af mannich-baser

Country Status (12)

Country	Link
EP (1)	EP0103366B1 (da)
JP (1)	JPS5933282A (da)
KR (1)	KR840005442A (da)
AT (1)	ATE18045T1 (da)
AU (1)	AU1682583A (da)
CA (1)	CA1249820A (da)
DE (1)	DE3362182D1 (da)
DK (1)	DK334383A (da)
ES (1)	ES8500938A1 (da)
GR (1)	GR79595B (da)
PT (1)	PT77042B (da)
ZA (1)	ZA835172B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8328240D0 (en) *	1983-10-21	1983-11-23	Smith Kline French Lab	Chemical process

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN151188B (da) *	1978-02-13	1983-03-05	Smith Kline French Lab

1983
- 1983-07-05 AT AT83303899T patent/ATE18045T1/de not_active IP Right Cessation
- 1983-07-05 EP EP83303899A patent/EP0103366B1/en not_active Expired
- 1983-07-05 DE DE8383303899T patent/DE3362182D1/de not_active Expired
- 1983-07-13 GR GR71931A patent/GR79595B/el unknown
- 1983-07-14 AU AU16825/83A patent/AU1682583A/en not_active Abandoned
- 1983-07-15 ZA ZA835172A patent/ZA835172B/xx unknown
- 1983-07-18 PT PT77042A patent/PT77042B/pt unknown
- 1983-07-18 KR KR1019830003287A patent/KR840005442A/ko not_active Withdrawn
- 1983-07-19 JP JP58132659A patent/JPS5933282A/ja active Pending
- 1983-07-19 CA CA000432768A patent/CA1249820A/en not_active Expired
- 1983-07-19 ES ES524242A patent/ES8500938A1/es not_active Expired
- 1983-07-20 DK DK334383A patent/DK334383A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
ZA835172B (en)	1985-02-27
EP0103366B1 (en)	1986-02-19
DK334383D0 (da)	1983-07-20
PT77042A (en)	1983-08-01
ES524242A0 (es)	1984-11-01
KR840005442A (ko)	1984-11-12
ES8500938A1 (es)	1984-11-01
GR79595B (da)	1984-10-31
JPS5933282A (ja)	1984-02-23
DE3362182D1 (en)	1986-03-27
ATE18045T1 (de)	1986-03-15
PT77042B (en)	1986-01-28
EP0103366A1 (en)	1984-03-21
AU1682583A (en)	1984-01-26
CA1249820A (en)	1989-02-07

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Legal Events

Date	Code	Title	Description
1987-04-06	AHB	Application shelved due to non-payment