DK3377653T3 - Fremgangsmåder til opnåelse og korrektion af biologisk sekvensinformation - Google Patents

Fremgangsmåder til opnåelse og korrektion af biologisk sekvensinformation

Info

Publication number
DK3377653T3
DK3377653T3 DK16865757.5T DK16865757T DK3377653T3 DK 3377653 T3 DK3377653 T3 DK 3377653T3 DK 16865757 T DK16865757 T DK 16865757T DK 3377653 T3 DK3377653 T3 DK 3377653T3
Authority
DK
Denmark
Prior art keywords
correction
obtaining
methods
sequence information
biological sequence
Prior art date
Application number
DK16865757.5T
Other languages
English (en)
Inventor
Yanyi Huang
Zitian Chen
Wenxiong Zhou
Haifeng Duan
Li Kang
Shuo Qiao
Original Assignee
Cygnus Biosciences Beijing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201510815685.XA external-priority patent/CN106755290B/zh
Priority claimed from CN201510822361.9A external-priority patent/CN106755292B/zh
Priority claimed from CN201510944878.5A external-priority patent/CN106874709B/zh
Priority claimed from CN201610899880.XA external-priority patent/CN107958138B/zh
Application filed by Cygnus Biosciences Beijing Co Ltd filed Critical Cygnus Biosciences Beijing Co Ltd
Application granted granted Critical
Publication of DK3377653T3 publication Critical patent/DK3377653T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Data Mining & Analysis (AREA)
  • Mathematical Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • Algebra (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Analysis (AREA)
  • Computational Mathematics (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Epidemiology (AREA)
DK16865757.5T 2015-11-19 2016-11-16 Fremgangsmåder til opnåelse og korrektion af biologisk sekvensinformation DK3377653T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN201510815685.XA CN106755290B (zh) 2015-11-19 2015-11-19 利用具有荧光切换性质荧光团的核苷酸底物分子进行测序的方法
CN201510822361.9A CN106755292B (zh) 2015-11-19 2015-11-19 一种磷酸修饰荧光团的核苷酸分子测序方法
CN201510944878.5A CN106874709B (zh) 2015-12-12 2015-12-12 测序结果中序列数据错误的检测和校正方法
CN201610899880.XA CN107958138B (zh) 2016-10-14 2016-10-14 一种从高通量dna测序的原始信号中读取序列信息的方法
PCT/CN2016/106117 WO2017084580A1 (en) 2015-11-19 2016-11-16 Methods for obtaining and correcting biological sequence information

Publications (1)

Publication Number Publication Date
DK3377653T3 true DK3377653T3 (da) 2025-12-01

Family

ID=58717327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16865757.5T DK3377653T3 (da) 2015-11-19 2016-11-16 Fremgangsmåder til opnåelse og korrektion af biologisk sekvensinformation

Country Status (7)

Country Link
US (3) US10738356B2 (da)
EP (1) EP3377653B1 (da)
CN (6) CN108699599B (da)
AU (2) AU2016356395B2 (da)
CA (1) CA3005671A1 (da)
DK (1) DK3377653T3 (da)
WO (1) WO2017084580A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11940413B2 (en) 2007-02-05 2024-03-26 IsoPlexis Corporation Methods and devices for sequencing nucleic acids in smaller batches
US9017973B2 (en) * 2008-03-19 2015-04-28 Intelligent Biosystems, Inc. Methods and compositions for incorporating nucleotides
CN106755292B (zh) * 2015-11-19 2019-06-18 赛纳生物科技(北京)有限公司 一种磷酸修饰荧光团的核苷酸分子测序方法
CN108699599B (zh) 2015-11-19 2026-01-06 赛纳生物科技(北京)有限公司 获得和校正生物序列信息的方法
WO2019191003A1 (en) 2018-03-26 2019-10-03 Ultima Genomics, Inc. Methods of sequencing nucleic acid molecules
CN108816300B (zh) 2018-07-02 2020-05-01 京东方科技集团股份有限公司 一种微流控芯片、功能装置及其制作方法
CN109738469A (zh) * 2018-12-29 2019-05-10 赛纳生物科技(北京)有限公司 一种fop表面微坑镀膜的致密性检测方法
CA3136034A1 (en) 2019-05-03 2020-11-12 Florian OBERSTRASS Methods of sequencing nucleic acid molecules
CN113141780B (zh) 2019-11-01 2025-01-10 京东方科技集团股份有限公司 薄膜晶体管及其制造方法和显示装置
CN113249455A (zh) * 2020-02-12 2021-08-13 赛纳生物科技(北京)有限公司 一种基因测序中获得背景信号的方法
CN111269799B (zh) * 2020-02-12 2023-07-04 赛纳生物科技(北京)有限公司 一种油封式生物化学芯片制备方法
CN113257351A (zh) * 2020-02-12 2021-08-13 赛纳生物科技(北京)有限公司 一种用于多碱基基因测序的基因文库及其构建方法
CN113249454A (zh) * 2020-02-12 2021-08-13 赛纳生物科技(北京)有限公司 一种多碱基基因测序中获得单位信号的方法
CN114196744B (zh) * 2020-09-18 2024-04-09 赛纳生物科技(北京)有限公司 一种多碱基基因测序中信号归一化的方法
CN119061125A (zh) 2021-07-21 2024-12-03 元素生物科学公司 用于核酸测序的方法
CN114507723B (zh) * 2022-01-28 2024-07-23 赛纳生物科技(北京)有限公司 一种测序信号归一化的方法
CN116430390B (zh) * 2023-06-13 2023-08-22 南京信息工程大学 一种面向资料同化的s波段双偏振雷达质量控制方法
WO2025235623A1 (en) * 2024-05-08 2025-11-13 Esbiolab, Llc Methods and systems for nucleic acid sequencing using an error-buffered coding scheme

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703052B1 (fr) 1993-03-26 1995-06-02 Pasteur Institut Nouvelle méthode de séquençage d'acides nucléiques.
NZ275194A (en) * 1993-09-27 1997-09-22 Arch Dev Corp Method and kit for nucleic acid sequencing
WO2000036152A1 (en) 1998-12-14 2000-06-22 Li-Cor, Inc. A system and methods for nucleic acid sequencing of single molecules by polymerase synthesis
CA2417368A1 (en) 2000-08-04 2002-02-14 Xin Lu Suppressor gene
US7223541B2 (en) 2001-08-29 2007-05-29 Ge Healthcare Bio-Sciences Corp. Terminal-phosphate-labeled nucleotides and methods of use
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
US20040152119A1 (en) 2003-02-05 2004-08-05 Anup Sood Solid phase sequencing
CA2515938A1 (en) 2003-02-12 2004-08-26 Genizon Svenska Ab Methods and means for nucleic acid sequencing
GB2398383B (en) * 2003-02-12 2005-03-09 Global Genomics Ab Method and means for nucleic acid sequencing
GB0324456D0 (en) * 2003-10-20 2003-11-19 Isis Innovation Parallel DNA sequencing methods
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
CA2624661C (en) 2005-11-23 2015-06-30 E.I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US8364417B2 (en) * 2007-02-15 2013-01-29 454 Life Sciences Corporation System and method to correct out of phase errors in DNA sequencing data by use of a recursive algorithm
EP2578702A1 (en) * 2006-02-16 2013-04-10 454 Life Sciences Corporation System and method for correcting primer extension errors in nucleic acid sequence data
CN101432439B (zh) * 2006-02-24 2013-07-24 考利达基因组股份有限公司 Dna阵列上的高通量基因组测序
EP2089517A4 (en) 2006-10-23 2010-10-20 Pacific Biosciences California POLYMERASEENZYME AND REAGENTS FOR ADVANCED NUCKIC ACID SEQUENCING
AU2008254986A1 (en) * 2007-05-14 2008-11-27 Insight Genetics, Inc. Methods of screening nucleic acids for single nucleotide variations
US9017973B2 (en) * 2008-03-19 2015-04-28 Intelligent Biosystems, Inc. Methods and compositions for incorporating nucleotides
EP2607496B1 (en) 2008-12-23 2014-07-16 Illumina, Inc. Methods useful in nucleic acid sequencing protocols
WO2011038241A1 (en) 2009-09-25 2011-03-31 President And Fellows Of Harvard College Nucleic acid amplification and sequencing by synthesis with fluorogenic nucleotides
US8965076B2 (en) * 2010-01-13 2015-02-24 Illumina, Inc. Data processing system and methods
US20120035062A1 (en) 2010-06-11 2012-02-09 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
CN101948519A (zh) 2010-09-08 2011-01-19 浙江海洋学院 厚壳贻贝足丝黏附蛋白及其编码序列和制备方法
CN102329884B (zh) * 2011-10-20 2013-05-08 东南大学 两核苷酸同时合成dna测序方法及其应用
CN104105797B (zh) * 2011-12-01 2016-08-31 吉纳普赛斯股份有限公司 用于高效电子测序与检测的系统和方法
WO2013154999A2 (en) 2012-04-09 2013-10-17 The Trustees Of Columbia University In The City Of New York Method of preparation of nanopore and uses thereof
CN102622534B (zh) * 2012-04-11 2015-09-30 哈尔滨工程大学 一种用于基因表达检测的dna高通测序数据校正方法
CN103602719B (zh) * 2013-04-07 2016-06-08 北京迈基诺基因科技有限责任公司 一种基因测序方法
CN104711340A (zh) 2013-12-17 2015-06-17 北京大学 一种转录组测序方法
CN104844674B (zh) * 2015-04-30 2019-11-12 赛纳生物科技(北京)有限公司 新型聚合酶底物:荧光可产生多聚磷酸末端标记核苷酸及其应用
CN104910229B (zh) * 2015-04-30 2019-11-12 赛纳生物科技(北京)有限公司 多聚磷酸末端荧光标记核苷酸及其应用
CN106755292B (zh) 2015-11-19 2019-06-18 赛纳生物科技(北京)有限公司 一种磷酸修饰荧光团的核苷酸分子测序方法
CN107958138B (zh) 2016-10-14 2019-06-18 赛纳生物科技(北京)有限公司 一种从高通量dna测序的原始信号中读取序列信息的方法
CN108699599B (zh) 2015-11-19 2026-01-06 赛纳生物科技(北京)有限公司 获得和校正生物序列信息的方法
CN106874709B (zh) 2015-12-12 2019-03-01 北京大学 测序结果中序列数据错误的检测和校正方法

Also Published As

Publication number Publication date
AU2016356395A1 (en) 2018-05-31
CN116083547B (zh) 2026-07-17
CN116426621A (zh) 2023-07-14
AU2021201594B2 (en) 2023-11-02
EP3377653B1 (en) 2025-10-29
CN116083547A (zh) 2023-05-09
CN116218970A (zh) 2023-06-06
US20180251831A1 (en) 2018-09-06
CN108699599B (zh) 2026-01-06
AU2016356395B2 (en) 2020-12-17
CN108699599A (zh) 2018-10-23
US11845984B2 (en) 2023-12-19
CA3005671A1 (en) 2017-05-26
EP3377653A1 (en) 2018-09-26
US20200407787A1 (en) 2020-12-31
US10738356B2 (en) 2020-08-11
WO2017084580A1 (en) 2017-05-26
CN208038441U (zh) 2018-11-02
EP3377653A4 (en) 2019-04-17
AU2021201594A1 (en) 2021-04-01
CN116240272A (zh) 2023-06-09
US20210017594A1 (en) 2021-01-21
US12012632B2 (en) 2024-06-18

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