DK3380080T3 - Topikal filmdannende spray - Google Patents

Topikal filmdannende spray Download PDF

Info

Publication number
DK3380080T3
DK3380080T3 DK16869283.8T DK16869283T DK3380080T3 DK 3380080 T3 DK3380080 T3 DK 3380080T3 DK 16869283 T DK16869283 T DK 16869283T DK 3380080 T3 DK3380080 T3 DK 3380080T3
Authority
DK
Denmark
Prior art keywords
topic
film
making spray
spray
making
Prior art date
Application number
DK16869283.8T
Other languages
English (en)
Inventor
S George Kottayil
Amresh Kumar
Prasanna Sunthankar
Vimal Kavuru
Original Assignee
Nortic Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nortic Holdings Inc filed Critical Nortic Holdings Inc
Application granted granted Critical
Publication of DK3380080T3 publication Critical patent/DK3380080T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
DK16869283.8T 2015-11-23 2016-11-23 Topikal filmdannende spray DK3380080T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562258672P 2015-11-23 2015-11-23
PCT/US2016/063618 WO2017091739A1 (en) 2015-11-23 2016-11-23 Topical film-forming spray

Publications (1)

Publication Number Publication Date
DK3380080T3 true DK3380080T3 (da) 2021-12-13

Family

ID=60039304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16869283.8T DK3380080T3 (da) 2015-11-23 2016-11-23 Topikal filmdannende spray

Country Status (17)

Country Link
US (4) US20170296484A1 (da)
EP (1) EP3380080B1 (da)
JP (1) JP7145363B2 (da)
KR (1) KR20180088415A (da)
CN (1) CN108738309B (da)
AU (1) AU2016359706B2 (da)
BR (1) BR112018010234A2 (da)
CA (1) CA3005150C (da)
DK (1) DK3380080T3 (da)
EA (1) EA201891225A1 (da)
ES (1) ES2901481T3 (da)
IL (1) IL259487A (da)
MX (1) MX387061B (da)
PH (1) PH12018550062A1 (da)
PL (1) PL3380080T3 (da)
WO (1) WO2017091739A1 (da)
ZA (1) ZA201804162B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3615445A4 (en) * 2017-04-24 2020-12-30 Joshua D. Levine PREVENTIVE PROCEDURES WITH THIXOTROPIC BINGHAM PLASTIC FLUID
EP3790856A4 (en) * 2018-05-08 2022-03-02 University of Connecticut LONG-ACTING LOCAL ANESTHETIC FORMULATION
JP7133981B2 (ja) * 2018-05-29 2022-09-09 小林製薬株式会社 外用組成物
AU2019299538B2 (en) * 2018-07-05 2025-05-08 Celista Pharmaceuticals Llc Testosterone and estradiol transdermal spray
EP3969057B1 (en) * 2019-05-17 2025-12-17 The Governing Council of the University of Toronto Sustained release local anesthetic hydrogel composition
US20220347132A1 (en) * 2019-09-19 2022-11-03 Celista Pharmaceuticals Llc Sprayable liquid lidocaine solution
KR20220070246A (ko) * 2019-09-23 2022-05-30 디디에스 리서치 인크. 침투 증진제를 갖는 지질 소포 조성물
WO2021101777A1 (en) * 2019-11-19 2021-05-27 Jie Zhang Self-solidifying topical formulations with local anesthetic
GB201918617D0 (en) * 2019-12-17 2020-01-29 Reckitt Benckiser Health Ltd Personal lubricant composition
US12257356B2 (en) * 2020-03-20 2025-03-25 Rachel Hankerson Systems and methods for applying antimicrobial hand barrier
DE202020003998U1 (de) * 2020-07-21 2021-10-25 Inclusion Gmbh Filmbildende Sprühpflaster zur dermalen und transdermalen Applikation von Stoffen enthaltend funktionale Hilfsstoffe zur molekularen Komplexierung
CN116887866A (zh) 2020-12-03 2023-10-13 巴特尔纪念研究院 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法
WO2022133629A1 (zh) * 2020-12-21 2022-06-30 江苏奇力康皮肤药业有限公司 一种喷雾型液体创可贴及其制备方法
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
CN113398100B8 (zh) * 2021-07-09 2022-11-22 临沂职业学院 一种油酸钠修饰的芍药苷壳聚糖纳米颗粒喷雾膜剂及其制备方法
WO2023250369A2 (en) * 2022-06-21 2023-12-28 Taro Pharmaceutical Industries Ltd. Topical naftifine compositions
WO2024098062A2 (en) * 2022-11-04 2024-05-10 Celista Pharmaceuticals Llc Topical oxybutynin for hot flashes
US20240299361A1 (en) * 2023-02-28 2024-09-12 Verté Therapeutics, Llc Veterinary transdermal gel comprising ondansetron, and related methods
WO2025034936A2 (en) * 2023-08-09 2025-02-13 Virpax Pharmaceuticals, Inc. Nsaid spray formulation and method
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems
CN120284921A (zh) * 2025-05-06 2025-07-11 北京弘德信医药科技有限公司 一种包含植物源几丁糖的氟比洛芬喷膜剂及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE431092B (sv) 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
US5632727A (en) 1988-10-03 1997-05-27 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
EP0560014A1 (en) 1992-03-12 1993-09-15 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
WO1997049391A1 (en) * 1996-06-24 1997-12-31 Euro-Celtique, S.A. Methods for providing safe local anesthesia
ATE343379T1 (de) 1998-08-20 2006-11-15 3M Innovative Properties Co Sprühverband und wirkstoffabgabesystem
DK1150661T3 (da) * 1999-02-05 2004-03-01 Cipla Ltd Topiske sprays der omfatter et filmdannende præparat
IL146190A0 (en) 1999-06-10 2002-07-25 Bridge Pharma Inc Dermal anesthetic agents
US6899897B2 (en) 2001-06-18 2005-05-31 Jaleva, Inc. Gum resin as a carrier for topical application of pharmacologically active agents
BRPI0415725A (pt) 2003-10-23 2006-12-19 Cipla Ltd formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativa
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
WO2007002518A1 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Delayed release or extended-delayed release dosage forms of pramipexole
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
CN101374488A (zh) * 2005-12-14 2009-02-25 扎尔斯制药公司 用于皮肤输送药物的促通量组合物及方法
PL2117521T3 (pl) * 2006-11-03 2012-11-30 Durect Corp Transdermalne systemy dostarczania zawierające bupiwakainę
US20100041704A1 (en) * 2007-01-12 2010-02-18 Aberg A K Gunnar Dermal compositions of substituted amides and the use thereof as medication for pain and pruritus
US9090737B2 (en) * 2007-11-13 2015-07-28 Surmodics, Inc. Viscous terpolymers as drug delivery platform
JP5833007B2 (ja) * 2009-08-31 2015-12-16 ドクター・レディーズ・ラボラトリーズ・リミテッド ステロイドを含む局所製剤
WO2011127456A2 (en) * 2010-04-09 2011-10-13 Pacira Pharmaceuticals, Inc. Method for formulating large diameter synthetic membrane vesicles
US9757456B2 (en) * 2010-09-14 2017-09-12 Nanologica Ab Super-saturating delivery vehicles for poorly water-soluble pharmaceutical and cosmetic active ingredients and suppression of crystallization of pharmaceutical active ingredients
WO2013049272A2 (en) * 2011-09-29 2013-04-04 Theraceutix, Llc Composition and method for treatment of symptoms associated with various skin conditions
MX2014015657A (es) * 2012-07-06 2015-03-20 Leo Pharma As Composicion topica que comprende un polimero formador de pelicula para liberar un ingrediente activo a la piel.
CN103933018A (zh) * 2013-01-18 2014-07-23 江苏康倍得药业有限公司 一种透皮给药系统
US20160008282A1 (en) * 2013-02-22 2016-01-14 The Board Of Trustees Of The Universityof Illinois Transdermal Drug Delivery Using Amphiphilic Dendron-Coil Micelles
AU2014223993B2 (en) * 2013-02-28 2016-09-08 Mira Pharma Corporation Injectable long-acting local anesthetic semi-solid formulations and its compostions
WO2015120412A1 (en) * 2014-02-07 2015-08-13 The Johns Hopkins University Compositions and methods for controlling fungal growth
SG10201808053XA (en) * 2014-03-19 2018-10-30 Infinity Pharmaceuticals Inc Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
CN104013574B (zh) * 2014-05-04 2017-04-12 莱普德制药有限公司 可温变性无痛纳米磺胺嘧啶金属化合物透明质酸的混悬制剂

Also Published As

Publication number Publication date
US20170296484A1 (en) 2017-10-19
PH12018550062A1 (en) 2018-11-12
JP7145363B2 (ja) 2022-10-03
US20220133642A1 (en) 2022-05-05
AU2016359706B2 (en) 2022-07-28
IL259487A (en) 2018-07-31
CA3005150C (en) 2022-08-30
CN108738309A (zh) 2018-11-02
ZA201804162B (en) 2019-09-25
CA3005150A1 (en) 2017-06-01
JP2019501215A (ja) 2019-01-17
EP3380080A4 (en) 2019-08-07
CN108738309B (zh) 2021-08-27
EP3380080B1 (en) 2021-09-22
WO2017091739A1 (en) 2017-06-01
PL3380080T3 (pl) 2022-03-07
BR112018010234A2 (pt) 2018-11-27
MX387061B (es) 2025-03-19
KR20180088415A (ko) 2018-08-03
WO2017091739A8 (en) 2018-09-13
US20170296485A1 (en) 2017-10-19
EA201891225A1 (ru) 2018-11-30
EP3380080A1 (en) 2018-10-03
ES2901481T3 (es) 2022-03-22
US20220133641A1 (en) 2022-05-05
AU2016359706A1 (en) 2018-05-31

Similar Documents

Publication Publication Date Title
FIC20230006I1 (fi) Vutrisiraani
EP3528716C0 (en) OSTEOTOMY SYSTEMS
DK3341056T3 (da) Sprøjteindretninger
EP3380080A4 (en) TOPICAL FILM-MAKING SPRAY
EP3383599A4 (en) ROBOT GRAB
EP3285633A4 (en) STEERING MICROENDOSCOPE
SI3139982T1 (sl) Razpršilnik
DK3297605T3 (da) Topiske, farmaceutiske sammesætninger
DK3365563T3 (da) Forbindelseskomponent
UA32259S (uk) Розприскувач
LT4242916T (lt) Purkštuvas
KR20180084876A (ko) 내플라즈마성 부재
DK3265057T3 (da) Topisk formulering
PT3212237T (pt) Formulação de metotrexato
EP3308781A4 (en) BLOOD PRESSURE CENTER
KR20180085035A (ko) 세탁기
EP3554717C0 (de) Sprühgerät
DK3173071T4 (da) Maropitantformulering
EP3355845A4 (en) OVERLAY
EP3323909A4 (en) COATING
BR112016027580A2 (pt) Formulação de ceritinib
EP3337527A4 (en) FUNCTION COATING
DK3257589T3 (da) Dyse
DK3218439T3 (da) Belægningssammensætninger
PL3064704T3 (pl) System zraszający