BRPI0415725A - formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativa - Google Patents
formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativaInfo
- Publication number
- BRPI0415725A BRPI0415725A BRPI0415725-7A BRPI0415725A BRPI0415725A BR PI0415725 A BRPI0415725 A BR PI0415725A BR PI0415725 A BRPI0415725 A BR PI0415725A BR PI0415725 A BRPI0415725 A BR PI0415725A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutically active
- active agent
- administering
- forming
- film
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- 239000013543 active substance Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 230000002821 anti-nucleating effect Effects 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002687 nonaqueous vehicle Substances 0.000 abstract 1
- 239000002667 nucleating agent Substances 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 239000007930 transdermal spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"FORMULAçãO ASPERGìVEL TRANSDéRMICA, MéTODO PARA ADMINISTRAR UM AGENTE FARMACEUTICAMENTE ATIVO E MéTODO PARA FORMAR UMA PELìCULA FARMACEUTICAMENTE ATIVA". São providos formulações aspergíveis transdérmicas contendo um agente farmaceuticamente ativo e métodos para administrar as mesmas. As formulações compreendem o agente farmaceuticamente ativo, um copolímero de VP/AV e um veículo não aquoso. As formulações compreendem ainda um agente anti-nucleante para evitar a recristalização do agente farmaceuticamente ativo e um intensificador de penetração para aumentar a taxa de liberação do fármaco através da pele. Quando da aplicação da pele, a presente formulação seca para prover uma película no local de tratamento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1122MU2003 | 2003-10-23 | ||
| PCT/GB2004/004487 WO2005041943A1 (en) | 2003-10-23 | 2004-10-21 | Transdermal pharmaceutical spray formulations comprising a vp/va copolymer and a non-aqueous vehicle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0415725A true BRPI0415725A (pt) | 2006-12-19 |
Family
ID=34531861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415725-7A BRPI0415725A (pt) | 2003-10-23 | 2004-10-21 | formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativa |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20070219171A1 (pt) |
| EP (1) | EP1686969A1 (pt) |
| JP (1) | JP2007509122A (pt) |
| CN (1) | CN100431531C (pt) |
| AP (1) | AP2006003628A0 (pt) |
| AR (1) | AR046146A1 (pt) |
| AU (1) | AU2004285335B2 (pt) |
| BR (1) | BRPI0415725A (pt) |
| CA (1) | CA2543245A1 (pt) |
| IL (1) | IL175094A0 (pt) |
| MA (1) | MA28167A1 (pt) |
| MX (1) | MXPA06004460A (pt) |
| NO (1) | NO20062234L (pt) |
| NZ (1) | NZ547376A (pt) |
| PA (1) | PA8615501A1 (pt) |
| PE (1) | PE20050443A1 (pt) |
| RU (1) | RU2006117527A (pt) |
| SM (1) | SM200400022A (pt) |
| SV (1) | SV2006001916A (pt) |
| TW (1) | TW200524635A (pt) |
| WO (1) | WO2005041943A1 (pt) |
| ZA (1) | ZA200604036B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0518769D0 (en) * | 2005-09-14 | 2005-10-19 | Medpharm Ltd | Topical formulations |
| US8481591B2 (en) * | 2010-11-01 | 2013-07-09 | Stiefel Research Australia Pty. Ltd. | Polymeric topical compositions |
| CN102018671B (zh) * | 2011-01-05 | 2012-07-25 | 浙江大学 | 一种雌二醇透皮喷雾剂及其制备方法 |
| US20150065449A1 (en) * | 2011-08-12 | 2015-03-05 | Florida State University Research Foundation, Inc. | Treating Amyloidoses With A Vitamin B12 Composition Including Melatonin, Resveratrol, and EGCG |
| GB201200062D0 (en) | 2012-01-04 | 2012-02-15 | Innotesto Bvba | Estradiol oromucosal liquid compositions |
| TWI516281B (zh) * | 2014-07-16 | 2016-01-11 | 健維生技有限公司 | 改良之睪固酮製劑製法及所得之睪固酮製劑 |
| KR20180088415A (ko) | 2015-11-23 | 2018-08-03 | 그레이스 테라퓨틱스 엘엘씨 | 국소적 막형성 스프레이 |
| EP3737374B1 (en) | 2018-01-10 | 2024-04-03 | Celista Pharmaceuticals Llc | Testosterone transdermal spray with film |
| WO2020010205A1 (en) * | 2018-07-05 | 2020-01-09 | Celista Pharmaceuticals Llc | Testosterone and estradiol transdermal spray |
| CN112206222A (zh) * | 2018-11-09 | 2021-01-12 | 北京德默高科医药技术有限公司 | 含有布洛芬结构类似物的多层经皮给药系统 |
| CN115154661A (zh) * | 2022-07-29 | 2022-10-11 | 广州莱度品牌管理有限公司 | 一种仿生角质膜的制备方法 |
| CN118593475B (zh) * | 2024-06-06 | 2025-07-25 | 暨南大学 | 用于治疗帕金森病的组合物、鼻喷雾剂及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01503281A (ja) * | 1987-05-27 | 1989-11-09 | ブルグハルト，クルト | 経皮治療に有効な医薬包帯剤およびこれを施用するためのデバイス |
| FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
| FR2739031B1 (fr) * | 1995-09-27 | 1997-11-21 | Lhd Lab Hygiene Dietetique | Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique |
| IT1299566B1 (it) * | 1998-07-17 | 2000-03-16 | Ifi Istituto Farmacoterapico I | Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina |
| CA2359640C (en) * | 1999-02-05 | 2008-11-18 | Cipla Limited | Topical sprays |
| US6962691B1 (en) * | 1999-05-20 | 2005-11-08 | U & I Pharmaceuticals Ltd. | Topical spray compositions |
| US6274167B1 (en) * | 2000-09-14 | 2001-08-14 | Vincent Margiotta | Topical anesthetic patch |
| US6528040B1 (en) * | 2001-01-18 | 2003-03-04 | Maurine Pearson | EMU oil-based formulations for use as an analgesic, anesthetic and antipruritic |
| DE10211832A1 (de) * | 2002-03-16 | 2003-10-02 | Lohmann Therapie Syst Lts | Hormonhaltiges transdermales therapeutisches System mit einem Wirkstoffreservoir auf der Basis von Vinylacetat-Vinylpyrrolidon-Copolymer mit verbesserter Kohäsion |
-
2004
- 2004-10-21 CN CNB2004800382138A patent/CN100431531C/zh not_active Expired - Fee Related
- 2004-10-21 WO PCT/GB2004/004487 patent/WO2005041943A1/en not_active Ceased
- 2004-10-21 ZA ZA200604036A patent/ZA200604036B/en unknown
- 2004-10-21 BR BRPI0415725-7A patent/BRPI0415725A/pt not_active Application Discontinuation
- 2004-10-21 AU AU2004285335A patent/AU2004285335B2/en not_active Ceased
- 2004-10-21 CA CA002543245A patent/CA2543245A1/en not_active Abandoned
- 2004-10-21 JP JP2006536176A patent/JP2007509122A/ja active Pending
- 2004-10-21 NZ NZ547376A patent/NZ547376A/xx not_active IP Right Cessation
- 2004-10-21 EP EP04769002A patent/EP1686969A1/en not_active Withdrawn
- 2004-10-21 MX MXPA06004460A patent/MXPA06004460A/es unknown
- 2004-10-21 AP AP2006003628A patent/AP2006003628A0/xx unknown
- 2004-10-21 RU RU2006117527/15A patent/RU2006117527A/ru not_active Application Discontinuation
- 2004-10-21 US US10/576,908 patent/US20070219171A1/en not_active Abandoned
- 2004-10-22 SM SM200400022A patent/SM200400022A/it unknown
- 2004-10-22 TW TW093132292A patent/TW200524635A/zh unknown
- 2004-10-22 PE PE2004001017A patent/PE20050443A1/es not_active Application Discontinuation
- 2004-10-22 PA PA20048615501A patent/PA8615501A1/es unknown
- 2004-10-22 SV SV2004001916A patent/SV2006001916A/es not_active Application Discontinuation
- 2004-10-22 AR ARP040103859A patent/AR046146A1/es unknown
-
2006
- 2006-04-23 IL IL175094A patent/IL175094A0/en unknown
- 2006-05-18 NO NO20062234A patent/NO20062234L/no not_active Application Discontinuation
- 2006-05-23 MA MA29045A patent/MA28167A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SM200400022B (it) | 2005-08-24 |
| WO2005041943A1 (en) | 2005-05-12 |
| HK1098351A1 (zh) | 2007-07-20 |
| KR20070000397A (ko) | 2007-01-02 |
| NO20062234L (no) | 2006-06-30 |
| JP2007509122A (ja) | 2007-04-12 |
| CN1897927A (zh) | 2007-01-17 |
| CN100431531C (zh) | 2008-11-12 |
| RU2006117527A (ru) | 2007-12-10 |
| MXPA06004460A (es) | 2006-06-27 |
| CA2543245A1 (en) | 2005-05-12 |
| AU2004285335A1 (en) | 2005-05-12 |
| AU2004285335B2 (en) | 2011-02-10 |
| ZA200604036B (en) | 2007-09-26 |
| PE20050443A1 (es) | 2005-06-14 |
| SM200400022A (it) | 2005-08-24 |
| SV2006001916A (es) | 2006-03-16 |
| PA8615501A1 (es) | 2005-10-25 |
| TW200524635A (en) | 2005-08-01 |
| EP1686969A1 (en) | 2006-08-09 |
| NZ547376A (en) | 2009-07-31 |
| US20070219171A1 (en) | 2007-09-20 |
| MA28167A1 (fr) | 2006-09-01 |
| AR046146A1 (es) | 2005-11-23 |
| AP2006003628A0 (en) | 2006-06-30 |
| IL175094A0 (en) | 2006-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |