DK3415915T3 - Fremgangsmåde til at forudsige respons til PARP-inhibitorer - Google Patents
Fremgangsmåde til at forudsige respons til PARP-inhibitorer Download PDFInfo
- Publication number
- DK3415915T3 DK3415915T3 DK18175350.0T DK18175350T DK3415915T3 DK 3415915 T3 DK3415915 T3 DK 3415915T3 DK 18175350 T DK18175350 T DK 18175350T DK 3415915 T3 DK3415915 T3 DK 3415915T3
- Authority
- DK
- Denmark
- Prior art keywords
- parp inhibitors
- predicting response
- predicting
- response
- parp
- Prior art date
Links
- 239000012661 PARP inhibitor Substances 0.000 title 1
- 229940121906 Poly ADP ribose polymerase inhibitor Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261602460P | 2012-02-23 | 2012-02-23 | |
| US201261604810P | 2012-02-29 | 2012-02-29 | |
| EP13755251.9A EP2817630B1 (en) | 2012-02-23 | 2013-02-22 | Methods for predicting anti-cancer response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3415915T3 true DK3415915T3 (da) | 2024-11-04 |
Family
ID=49083171
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13755251.9T DK2817630T3 (da) | 2012-02-23 | 2013-02-22 | Fremgangsmåder til at forudsige en anti-cancer-reaktion |
| DK18175350.0T DK3415915T3 (da) | 2012-02-23 | 2013-02-22 | Fremgangsmåde til at forudsige respons til PARP-inhibitorer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13755251.9T DK2817630T3 (da) | 2012-02-23 | 2013-02-22 | Fremgangsmåder til at forudsige en anti-cancer-reaktion |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10190160B2 (da) |
| EP (3) | EP2817630B1 (da) |
| AU (1) | AU2013226400B2 (da) |
| CA (2) | CA3080441C (da) |
| DK (2) | DK2817630T3 (da) |
| ES (2) | ES2997859T3 (da) |
| FI (1) | FI3415915T3 (da) |
| NZ (1) | NZ628813A (da) |
| WO (1) | WO2013130347A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2704303T3 (es) | 2010-08-24 | 2019-03-15 | Dana Farber Cancer Inst Inc | Procedimientos para la predicción de una respuesta contra el cáncer |
| EP4563709A3 (en) | 2011-06-17 | 2025-09-03 | Myriad Genetics, Inc. | Methods and materials for assessing allelic imbalance |
| CN107267598B (zh) | 2011-12-21 | 2022-03-25 | 美瑞德生物工程公司 | 用于评估杂合性丢失的方法与材料 |
| WO2013130347A1 (en) | 2012-02-23 | 2013-09-06 | The Children's Hospital Corporation | Methods for predicting anti-cancer response |
| ES2658867T3 (es) | 2012-06-07 | 2018-03-12 | Institut Curie | Métodos para detectar la inactivación de la ruta de recombinación homóloga (BRCA1/2) en tumores humanos |
| WO2014160080A1 (en) | 2013-03-14 | 2014-10-02 | Children's Medical Center Corporation | Cancer diagnosis, treatment selection and treatment |
| DK2981624T3 (da) * | 2013-04-05 | 2020-03-02 | Myriad Genetics Inc | Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling |
| EP3080292B1 (en) | 2013-12-09 | 2022-02-02 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| EP3094752A4 (en) * | 2014-01-16 | 2017-08-16 | Clovis Oncology, Inc. | Use of parp inhibitors to treat breast or ovarian cancer patients showing a loss of heterozygosity |
| EP4234711B1 (en) * | 2014-08-15 | 2025-05-28 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| US20160160294A1 (en) * | 2014-12-08 | 2016-06-09 | Tesaro | Methods and materials for predicting response to niraparib |
| JP7224185B2 (ja) * | 2016-05-01 | 2023-02-17 | ゲノム・リサーチ・リミテッド | Ｄｎａサンプルを特徴付ける方法 |
| EP3452937B1 (en) | 2016-05-01 | 2025-10-22 | Genome Research Limited | Method of characterising a dna sample |
| EP3945525A1 (en) | 2020-07-27 | 2022-02-02 | Sophia Genetics S.A. | Methods for identifying chromosomal spatial instability such as homologous repair deficiency in low coverage next-generation sequencing data |
| EP4229214A4 (en) * | 2020-10-14 | 2024-08-28 | Imprimed, Inc. | METHODS AND SYSTEMS FOR PREDICTING IN VIVO RESPONSE TO DRUG THERAPIES |
| US20220370631A1 (en) * | 2021-05-03 | 2022-11-24 | Mersana Therapeutics, Inc. | Combination therapy of carboplatin and napi2b-targeted polymer antibody-drug conjugate for the treatment of ovarian cancer |
| WO2023239343A1 (en) * | 2022-06-06 | 2023-12-14 | Memorial Sloan-Kettering Cancer Center | Methods including geometric network analysis for selecting patients with high grade serous carcinoma of the ovary treated with immune checkpoint blockade therapy |
| WO2024083971A1 (en) | 2022-10-19 | 2024-04-25 | Vib Vzw | Method of determining loss of heterozygosity status of a tumor |
| WO2025078387A1 (en) | 2023-10-10 | 2025-04-17 | Vib Vzw | Method of detecting loss of heterozygosity status of a tumor |
| WO2025078404A1 (en) | 2023-10-10 | 2025-04-17 | Vib Vzw | Methods of determining response of a tumor to dna-damaging agents or to agents inhibiting or impairing dna repair |
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| WO2013130347A1 (en) | 2012-02-23 | 2013-09-06 | The Children's Hospital Corporation | Methods for predicting anti-cancer response |
| ES2658867T3 (es) | 2012-06-07 | 2018-03-12 | Institut Curie | Métodos para detectar la inactivación de la ruta de recombinación homóloga (BRCA1/2) en tumores humanos |
| DK2981624T3 (da) | 2013-04-05 | 2020-03-02 | Myriad Genetics Inc | Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling |
| EP3080292B1 (en) | 2013-12-09 | 2022-02-02 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
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-
2013
- 2013-02-22 WO PCT/US2013/027295 patent/WO2013130347A1/en not_active Ceased
- 2013-02-22 DK DK13755251.9T patent/DK2817630T3/da active
- 2013-02-22 EP EP13755251.9A patent/EP2817630B1/en active Active
- 2013-02-22 EP EP18175350.0A patent/EP3415915B1/en active Active
- 2013-02-22 NZ NZ628813A patent/NZ628813A/en not_active IP Right Cessation
- 2013-02-22 DK DK18175350.0T patent/DK3415915T3/da active
- 2013-02-22 CA CA3080441A patent/CA3080441C/en active Active
- 2013-02-22 CA CA2864481A patent/CA2864481C/en active Active
- 2013-02-22 ES ES18175350T patent/ES2997859T3/es active Active
- 2013-02-22 AU AU2013226400A patent/AU2013226400B2/en active Active
- 2013-02-22 ES ES13755251.9T patent/ES2687024T3/es active Active
- 2013-02-22 FI FIEP18175350.0T patent/FI3415915T3/fi active
- 2013-02-22 EP EP24202895.9A patent/EP4462120A3/en active Pending
-
2014
- 2014-08-22 US US14/466,208 patent/US10190160B2/en active Active
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2018
- 2018-12-28 US US16/235,247 patent/US11299782B2/en active Active
-
2022
- 2022-03-01 US US17/683,656 patent/US20220186311A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3080441C (en) | 2026-01-06 |
| US10190160B2 (en) | 2019-01-29 |
| AU2013226400B2 (en) | 2018-09-06 |
| EP2817630B1 (en) | 2018-07-11 |
| EP3415915A1 (en) | 2018-12-19 |
| ES2687024T3 (es) | 2018-10-23 |
| FI3415915T3 (fi) | 2024-11-29 |
| EP4462120A3 (en) | 2025-01-08 |
| EP2817630A1 (en) | 2014-12-31 |
| NZ628813A (en) | 2015-10-30 |
| CA3080441A1 (en) | 2013-09-06 |
| CA2864481A1 (en) | 2013-09-06 |
| US20150038340A1 (en) | 2015-02-05 |
| AU2013226400A1 (en) | 2014-09-04 |
| DK2817630T3 (da) | 2018-10-08 |
| US20190136318A1 (en) | 2019-05-09 |
| WO2013130347A1 (en) | 2013-09-06 |
| EP4462120A2 (en) | 2024-11-13 |
| EP2817630A4 (en) | 2015-10-28 |
| US20220186311A1 (en) | 2022-06-16 |
| ES2997859T3 (en) | 2025-02-18 |
| US11299782B2 (en) | 2022-04-12 |
| EP3415915B1 (en) | 2024-10-23 |
| CA2864481C (en) | 2020-07-14 |
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