DK3452513T3 - Humaniserede anti-il-ir3-antistoffer - Google Patents

Humaniserede anti-il-ir3-antistoffer Download PDF

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Publication number
DK3452513T3
DK3452513T3 DK17724778.0T DK17724778T DK3452513T3 DK 3452513 T3 DK3452513 T3 DK 3452513T3 DK 17724778 T DK17724778 T DK 17724778T DK 3452513 T3 DK3452513 T3 DK 3452513T3
Authority
DK
Denmark
Prior art keywords
antibodies
humanized anti
humanized
Prior art date
Application number
DK17724778.0T
Other languages
English (en)
Inventor
Stephan Fischer
Michael Brandt
Linda Veronique Kazandjian
Original Assignee
Sanofi Biotechnology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Biotechnology filed Critical Sanofi Biotechnology
Application granted granted Critical
Publication of DK3452513T3 publication Critical patent/DK3452513T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17724778.0T 2016-05-06 2017-05-08 Humaniserede anti-il-ir3-antistoffer DK3452513T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16168617.5A EP3241845A1 (en) 2016-05-06 2016-05-06 Humanized anti-il-1r3 antibodies
PCT/EP2017/060925 WO2017191325A1 (en) 2016-05-06 2017-05-08 Humanized anti-il-1r3 antibodies

Publications (1)

Publication Number Publication Date
DK3452513T3 true DK3452513T3 (da) 2024-07-15

Family

ID=55919721

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17724778.0T DK3452513T3 (da) 2016-05-06 2017-05-08 Humaniserede anti-il-ir3-antistoffer

Country Status (24)

Country Link
US (3) US11203642B2 (da)
EP (3) EP3241845A1 (da)
JP (3) JP7038462B2 (da)
KR (3) KR102550643B1 (da)
CN (3) CN116178549A (da)
AU (2) AU2017260399B2 (da)
CA (1) CA3022657A1 (da)
DK (1) DK3452513T3 (da)
EA (1) EA201892541A1 (da)
ES (1) ES2982075T3 (da)
FI (1) FI3452513T3 (da)
HR (1) HRP20240961T1 (da)
HU (1) HUE066965T2 (da)
IL (2) IL262776B2 (da)
LT (1) LT3452513T (da)
MX (2) MX2018013517A (da)
NZ (1) NZ748130A (da)
PL (1) PL3452513T3 (da)
PT (1) PT3452513T (da)
RS (1) RS65804B1 (da)
SG (1) SG11201809764XA (da)
SI (1) SI3452513T1 (da)
WO (1) WO2017191325A1 (da)
ZA (1) ZA201807167B (da)

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Also Published As

Publication number Publication date
KR20230107695A (ko) 2023-07-17
EP3452513B1 (en) 2024-04-17
PT3452513T (pt) 2024-07-09
SI3452513T1 (sl) 2024-10-30
PL3452513T3 (pl) 2024-09-16
KR102550643B1 (ko) 2023-07-03
KR102381257B1 (ko) 2022-04-04
US11203642B2 (en) 2021-12-21
CN109415442B (zh) 2022-12-23
IL297527B2 (en) 2026-08-01
ES2982075T3 (es) 2024-10-14
CN109415442A (zh) 2019-03-01
IL297527A (en) 2022-12-01
HRP20240961T1 (hr) 2024-10-25
JP2024102134A (ja) 2024-07-30
RS65804B1 (sr) 2024-08-30
MX2018013517A (es) 2019-07-08
FI3452513T3 (fi) 2024-07-05
CA3022657A1 (en) 2017-11-09
EP4434540A3 (en) 2024-12-25
SG11201809764XA (en) 2018-12-28
IL262776B2 (en) 2023-03-01
EP3241845A1 (en) 2017-11-08
JP7480199B2 (ja) 2024-05-09
US20190194336A1 (en) 2019-06-27
KR20220042499A (ko) 2022-04-05
AU2024204004A1 (en) 2024-08-01
JP7038462B2 (ja) 2022-03-18
AU2017260399B2 (en) 2024-03-14
US20240409644A1 (en) 2024-12-12
LT3452513T (lt) 2024-08-12
BR112018072681A2 (pt) 2019-02-19
JP2019516787A (ja) 2019-06-20
HUE066965T2 (hu) 2024-09-28
IL262776A (en) 2018-12-31
WO2017191325A9 (en) 2018-01-04
EA201892541A1 (ru) 2019-03-29
NZ748130A (en) 2022-08-26
BR112018072681A8 (pt) 2023-04-11
CN116178549A (zh) 2023-05-30
CN116178548A (zh) 2023-05-30
JP2022078191A (ja) 2022-05-24
MX2023002554A (es) 2023-04-10
WO2017191325A1 (en) 2017-11-09
IL262776B (en) 2022-11-01
IL297527B1 (en) 2026-04-01
ZA201807167B (en) 2019-06-26
US12024564B2 (en) 2024-07-02
EP3452513A1 (en) 2019-03-13
NZ788000A (en) 2025-06-27
US20220089751A1 (en) 2022-03-24
KR20190004762A (ko) 2019-01-14
AU2017260399A1 (en) 2018-11-29
EP4434540A2 (en) 2024-09-25

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