DK3481826T3 - Tyrosinkinaseinhibitorer - Google Patents
Tyrosinkinaseinhibitorer Download PDFInfo
- Publication number
- DK3481826T3 DK3481826T3 DK17742601.2T DK17742601T DK3481826T3 DK 3481826 T3 DK3481826 T3 DK 3481826T3 DK 17742601 T DK17742601 T DK 17742601T DK 3481826 T3 DK3481826 T3 DK 3481826T3
- Authority
- DK
- Denmark
- Prior art keywords
- tyrosinkinase
- inhibitors
- tyrosinkinase inhibitors
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662360297P | 2016-07-08 | 2016-07-08 | |
| PCT/US2017/041396 WO2018009938A1 (en) | 2016-07-08 | 2017-07-10 | Tyrosine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3481826T3 true DK3481826T3 (da) | 2022-01-10 |
Family
ID=59383641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17742601.2T DK3481826T3 (da) | 2016-07-08 | 2017-07-10 | Tyrosinkinaseinhibitorer |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10130623B2 (da) |
| EP (1) | EP3481826B1 (da) |
| JP (2) | JP7061993B2 (da) |
| CA (1) | CA3030283A1 (da) |
| DK (1) | DK3481826T3 (da) |
| ES (1) | ES2903526T3 (da) |
| WO (1) | WO2018009938A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3481826B1 (en) | 2016-07-08 | 2021-11-03 | Rigel Pharmaceuticals, Inc. | Tyrosine kinase inhibitors |
| WO2022013684A1 (en) | 2020-07-11 | 2022-01-20 | Pfizer Inc. | Antiviral heteroaryl ketone derivatives |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| WO2022143864A1 (zh) * | 2020-12-31 | 2022-07-07 | 江苏先声药业有限公司 | 三环类化合物及用途 |
| KR102694996B1 (ko) * | 2021-10-27 | 2024-08-13 | 상하이 지멍 바이오파마 아이엔씨 | 칼륨 채널 조절제로 사용되는 화합물 및 이의 제조 및 응용 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003137866A (ja) | 2001-11-01 | 2003-05-14 | Sankyo Co Ltd | フェニレンジアミン誘導体 |
| CN102127078A (zh) | 2005-07-14 | 2011-07-20 | 安斯泰来制药株式会社 | Janus激酶3的杂环类抑制剂 |
| RU2457203C2 (ru) | 2006-12-27 | 2012-07-27 | Санофи-Авентис | Замещенные циклоалкиламином производные изохинолона |
| EP3628665B1 (en) | 2011-04-01 | 2022-11-02 | University of Utah Research Foundation | Substituted n-phenylpyrimidin-2-amine analogs as inhibitors of the axl kinase |
| WO2014164729A1 (en) * | 2013-03-12 | 2014-10-09 | Arqule, Inc. | Substituted tricyclic pyrazolo-pyrimidine compounds |
| CN106795154B (zh) | 2014-09-02 | 2019-07-05 | 皮埃尔法布雷医药公司 | 用于治疗癌症的异喹啉酮衍生物 |
| US9840503B2 (en) * | 2015-05-11 | 2017-12-12 | Incyte Corporation | Heterocyclic compounds and uses thereof |
| EP3481826B1 (en) | 2016-07-08 | 2021-11-03 | Rigel Pharmaceuticals, Inc. | Tyrosine kinase inhibitors |
-
2017
- 2017-07-10 EP EP17742601.2A patent/EP3481826B1/en active Active
- 2017-07-10 US US15/645,775 patent/US10130623B2/en active Active
- 2017-07-10 WO PCT/US2017/041396 patent/WO2018009938A1/en not_active Ceased
- 2017-07-10 JP JP2019500387A patent/JP7061993B2/ja not_active Expired - Fee Related
- 2017-07-10 CA CA3030283A patent/CA3030283A1/en active Pending
- 2017-07-10 DK DK17742601.2T patent/DK3481826T3/da active
- 2017-07-10 ES ES17742601T patent/ES2903526T3/es active Active
-
2018
- 2018-10-04 US US16/151,959 patent/US10434096B2/en active Active
-
2019
- 2019-09-19 US US16/575,852 patent/US11110082B2/en not_active Expired - Fee Related
-
2021
- 2021-09-02 US US17/465,662 patent/US11672791B2/en active Active
- 2021-09-10 JP JP2021147487A patent/JP2021185203A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021185203A (ja) | 2021-12-09 |
| US20200078348A1 (en) | 2020-03-12 |
| WO2018009938A1 (en) | 2018-01-11 |
| US20230012676A1 (en) | 2023-01-19 |
| US20180008589A1 (en) | 2018-01-11 |
| US11110082B2 (en) | 2021-09-07 |
| CA3030283A1 (en) | 2018-01-11 |
| US10434096B2 (en) | 2019-10-08 |
| US20190099411A1 (en) | 2019-04-04 |
| EP3481826A1 (en) | 2019-05-15 |
| US10130623B2 (en) | 2018-11-20 |
| JP2019520397A (ja) | 2019-07-18 |
| US11672791B2 (en) | 2023-06-13 |
| EP3481826B1 (en) | 2021-11-03 |
| JP7061993B2 (ja) | 2022-05-02 |
| ES2903526T3 (es) | 2022-04-04 |
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