DK3486324T3 - Fremgangsmåde til fremstilling af aminer fra carbonylforbindelser ved transaminasereaktion under saltudfældning - Google Patents
Fremgangsmåde til fremstilling af aminer fra carbonylforbindelser ved transaminasereaktion under saltudfældning Download PDFInfo
- Publication number
- DK3486324T3 DK3486324T3 DK17202282.4T DK17202282T DK3486324T3 DK 3486324 T3 DK3486324 T3 DK 3486324T3 DK 17202282 T DK17202282 T DK 17202282T DK 3486324 T3 DK3486324 T3 DK 3486324T3
- Authority
- DK
- Denmark
- Prior art keywords
- amines
- preparation
- reaction under
- carbonyl compounds
- salt precipitation
- Prior art date
Links
- 102000003929 Transaminases Human genes 0.000 title 1
- 108090000340 Transaminases Proteins 0.000 title 1
- 150000001412 amines Chemical class 0.000 title 1
- 150000001728 carbonyl compounds Chemical class 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000001556 precipitation Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
- C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17202282.4A EP3486324B1 (en) | 2017-11-17 | 2017-11-17 | Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3486324T3 true DK3486324T3 (da) | 2020-09-14 |
Family
ID=60654601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17202282.4T DK3486324T3 (da) | 2017-11-17 | 2017-11-17 | Fremgangsmåde til fremstilling af aminer fra carbonylforbindelser ved transaminasereaktion under saltudfældning |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12018303B2 (da) |
| EP (1) | EP3486324B1 (da) |
| JP (1) | JP7250807B2 (da) |
| KR (1) | KR102554463B1 (da) |
| CN (1) | CN111465699B (da) |
| DK (1) | DK3486324T3 (da) |
| ES (1) | ES2816102T3 (da) |
| WO (1) | WO2019096973A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3486324B1 (en) * | 2017-11-17 | 2020-06-10 | Enzymicals AG | Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation |
| EP4050100A4 (en) * | 2019-10-25 | 2022-11-09 | Asymchem Laboratories (Fuxin) Co., Ltd. | TRANSAMINASE MUTANT AND USE THEREOF |
| CN111235127B (zh) * | 2020-04-29 | 2020-08-14 | 凯莱英医药集团（天津）股份有限公司 | 转氨酶突变体及其应用 |
| CN113881720B (zh) * | 2020-12-31 | 2023-08-25 | 上海合全药物研发有限公司 | 一种转氨酶及使用其进行催化制备的方法 |
| CN114277010B (zh) * | 2021-12-24 | 2025-09-09 | 上海合全药物研发有限公司 | 转氨酶及其在制备光学纯手性胺中的应用 |
| CN117567270B (zh) * | 2023-11-20 | 2024-08-09 | 江南大学 | 一种醇胺-壬二酸超分子离子盐及其制备和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007042600A1 (de) | 2007-09-07 | 2009-03-12 | Evonik Degussa Gmbh | Verfahren zur Herstellung von enantiomerenangereichten Aminen |
| SG178842A1 (en) * | 2009-09-02 | 2012-04-27 | Lonza Ag | A process for the identification and preparation of a (r)-specific omega-transaminase |
| KR20120083908A (ko) | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
| ES2650245T3 (es) | 2010-07-14 | 2018-01-17 | Dpx Holdings B.V. | Método enzimático para aminación (R)-selectiva |
| EP3486324B1 (en) * | 2017-11-17 | 2020-06-10 | Enzymicals AG | Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation |
-
2017
- 2017-11-17 EP EP17202282.4A patent/EP3486324B1/en active Active
- 2017-11-17 ES ES17202282T patent/ES2816102T3/es active Active
- 2017-11-17 DK DK17202282.4T patent/DK3486324T3/da active
-
2018
- 2018-11-16 WO PCT/EP2018/081517 patent/WO2019096973A1/en not_active Ceased
- 2018-11-16 KR KR1020207017054A patent/KR102554463B1/ko active Active
- 2018-11-16 JP JP2020545446A patent/JP7250807B2/ja active Active
- 2018-11-16 CN CN201880074226.2A patent/CN111465699B/zh active Active
- 2018-11-16 US US16/764,476 patent/US12018303B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN111465699B (zh) | 2024-09-20 |
| EP3486324A1 (en) | 2019-05-22 |
| KR20200110641A (ko) | 2020-09-24 |
| US20230167472A9 (en) | 2023-06-01 |
| EP3486324B1 (en) | 2020-06-10 |
| JP2021503306A (ja) | 2021-02-12 |
| JP7250807B2 (ja) | 2023-04-03 |
| ES2816102T3 (es) | 2021-03-31 |
| US20220162654A1 (en) | 2022-05-26 |
| WO2019096973A1 (en) | 2019-05-23 |
| US12018303B2 (en) | 2024-06-25 |
| CN111465699A (zh) | 2020-07-28 |
| KR102554463B1 (ko) | 2023-07-12 |
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