DK3520805T3 - Sammensætninger til behandling af myelofibrose - Google Patents

Sammensætninger til behandling af myelofibrose Download PDF

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Publication number
DK3520805T3
DK3520805T3 DK19161424.7T DK19161424T DK3520805T3 DK 3520805 T3 DK3520805 T3 DK 3520805T3 DK 19161424 T DK19161424 T DK 19161424T DK 3520805 T3 DK3520805 T3 DK 3520805T3
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Denmark
Prior art keywords
myelofibrose
compositions
treatment
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DK19161424.7T
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English (en)
Inventor
Jasbir Seehra
Robert Scott Pearsall
Ravindra Kumar
Naga Venkata Sai Rajasekhar Suragani
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Acceleron Pharma Inc
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Publication of DK3520805T3 publication Critical patent/DK3520805T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103Receptor protein serine/threonine kinase (2.7.11.30)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK19161424.7T 2011-10-17 2012-10-17 Sammensætninger til behandling af myelofibrose DK3520805T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161547932P 2011-10-17 2011-10-17
EP12842601.2A EP2797620B1 (en) 2011-10-17 2012-10-17 Compositions for treating iron overload in thalassemia

Publications (1)

Publication Number Publication Date
DK3520805T3 true DK3520805T3 (da) 2021-04-19

Family

ID=48141315

Family Applications (2)

Application Number Title Priority Date Filing Date
DK19161424.7T DK3520805T3 (da) 2011-10-17 2012-10-17 Sammensætninger til behandling af myelofibrose
DK21153891.3T DK3875104T3 (da) 2011-10-17 2012-10-17 Sammensætninger til behandling af ineffektiv erytropoiese

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK21153891.3T DK3875104T3 (da) 2011-10-17 2012-10-17 Sammensætninger til behandling af ineffektiv erytropoiese

Country Status (13)

Country Link
US (4) US20130243743A1 (da)
EP (3) EP2797620B1 (da)
JP (4) JP6092883B2 (da)
KR (4) KR20140084211A (da)
CN (3) CN107837390A (da)
AU (4) AU2012326207B2 (da)
BR (3) BR122019023174B1 (da)
CA (1) CA2852683A1 (da)
DK (2) DK3520805T3 (da)
EA (2) EA034563B1 (da)
ES (3) ES3010483T3 (da)
HK (2) HK1250341A1 (da)
WO (1) WO2013059347A1 (da)

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MA40008A (fr) 2014-06-13 2021-05-05 Acceleron Pharma Inc Antagoniste actrii pour le traitement et la prevention d'un ulcere cutane chez un sujet ayant l'anemie
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TWI730949B (zh) * 2014-12-03 2021-06-21 美商西建公司 活化素-actrii拮抗劑及治療貧血之用途
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JP6976859B2 (ja) * 2015-05-13 2021-12-08 セルジーン コーポレイション ActRIIリガンドトラップを用いたβ−サラセミアの治療
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Also Published As

Publication number Publication date
AU2017201580B2 (en) 2018-07-12
HK1203413A1 (en) 2015-10-30
ES2869168T3 (es) 2021-10-25
EA202090053A3 (ru) 2020-06-30
BR112014009528B1 (pt) 2020-12-29
EA201490809A1 (ru) 2014-09-30
KR20200019261A (ko) 2020-02-21
AU2018247262A1 (en) 2018-11-01
HK1250341A1 (zh) 2018-12-14
KR102079482B1 (ko) 2020-02-19
US20210207107A1 (en) 2021-07-08
ES3010483T3 (en) 2025-04-03
CN107837390A (zh) 2018-03-27
JP2014530253A (ja) 2014-11-17
CN107693776A (zh) 2018-02-16
AU2012326207A1 (en) 2014-05-15
EP3520805A1 (en) 2019-08-07
BR112014009528A2 (pt) 2017-05-09
JP6092883B2 (ja) 2017-03-08
KR20190105113A (ko) 2019-09-11
CA2852683A1 (en) 2013-04-25
EP2797620B1 (en) 2019-04-24
AU2012326207B2 (en) 2016-12-15
EA034563B1 (ru) 2020-02-20
EA202090053A2 (ru) 2020-04-30
ES2741477T3 (es) 2020-02-11
JP2020186277A (ja) 2020-11-19
EP3875104A1 (en) 2021-09-08
BR112014009528A8 (pt) 2019-12-10
AU2018247262B2 (en) 2020-12-24
BR122019023174B1 (pt) 2021-02-23
US20170137791A1 (en) 2017-05-18
CN103987403A (zh) 2014-08-13
JP2017101060A (ja) 2017-06-08
AU2017201580A1 (en) 2017-03-30
EP2797620A1 (en) 2014-11-05
KR20220075438A (ko) 2022-06-08
WO2013059347A1 (en) 2013-04-25
BR122019023166B1 (pt) 2021-02-23
EP3875104B1 (en) 2025-01-22
EP2797620A4 (en) 2015-05-20
EP3520805B1 (en) 2021-03-10
JP6383821B2 (ja) 2018-08-29
US20130243743A1 (en) 2013-09-19
HK1252940A1 (zh) 2019-06-06
DK3875104T3 (da) 2025-02-03
KR20140084211A (ko) 2014-07-04
JP2018165287A (ja) 2018-10-25
JP6796626B2 (ja) 2020-12-09
AU2020286229A1 (en) 2021-01-07
CN103987403B (zh) 2017-12-01
US20170327800A1 (en) 2017-11-16

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