DK3523339T3 - Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler - Google Patents

Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler

Info

Publication number
DK3523339T3
DK3523339T3 DK17859078.2T DK17859078T DK3523339T3 DK 3523339 T3 DK3523339 T3 DK 3523339T3 DK 17859078 T DK17859078 T DK 17859078T DK 3523339 T3 DK3523339 T3 DK 3523339T3
Authority
DK
Denmark
Prior art keywords
biomimetric
block copolymers
lubricant block
lubricants
interface
Prior art date
Application number
DK17859078.2T
Other languages
English (en)
Inventor
David Putnam
Lawrence Bonassar
Zhexun Sun
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Application granted granted Critical
Publication of DK3523339T3 publication Critical patent/DK3523339T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
    • C08F220/285—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing a polyether chain in the alcohol moiety
    • C08F220/286—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing a polyether chain in the alcohol moiety and containing polyethylene oxide in the alcohol moiety, e.g. methoxy polyethylene glycol (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2438/00—Living radical polymerisation
    • C08F2438/03—Use of a di- or tri-thiocarbonylthio compound, e.g. di- or tri-thioester, di- or tri-thiocarbamate, or a xanthate as chain transfer agent, e.g . Reversible Addition Fragmentation chain Transfer [RAFT] or Macromolecular Design via Interchange of Xanthates [MADIX]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10—Copolymer characterised by the proportions of the comonomers expressed as molar percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/50—Chemical modification of a polymer wherein the polymer is a copolymer and the modification is taking place only on one or more of the monomers present in minority

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
DK17859078.2T 2016-10-04 2017-10-04 Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler DK3523339T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662403962P 2016-10-04 2016-10-04
PCT/US2017/055057 WO2018067648A1 (en) 2016-10-04 2017-10-04 Lubricating block copolymers and their use as biomimetic boundary lubricants

Publications (1)

Publication Number Publication Date
DK3523339T3 true DK3523339T3 (da) 2025-08-25

Family

ID=61831218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17859078.2T DK3523339T3 (da) 2016-10-04 2017-10-04 Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler

Country Status (8)

Country Link
US (2) US11376276B2 (da)
EP (1) EP3523339B1 (da)
JP (2) JP7085536B2 (da)
CN (2) CN110050003B (da)
DK (1) DK3523339T3 (da)
ES (1) ES3039978T3 (da)
PL (1) PL3523339T3 (da)
WO (1) WO2018067648A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3523339T3 (da) 2016-10-04 2025-08-25 Univ Cornell Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler
CN110522953B (zh) * 2018-05-24 2022-02-15 中国科学院兰州化学物理研究所 一种仿生关节润滑剂及其制备方法
JP7725041B2 (ja) * 2023-07-26 2025-08-19 株式会社高研 コラーゲン結合型膜透過性ペプチド、並びに、該ペプチド及びコラーゲン若しくはコラーゲン誘導体を含む運搬体
CN121773146A (zh) * 2023-08-11 2026-03-31 科凝生物医药科技(杭州)有限公司 嵌段式共聚物的润滑组合物及其用途
WO2025250734A1 (en) * 2024-05-29 2025-12-04 University Of Florida Research Foundation, Inc. High molecular weight polymers and methods of making the same

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3110615A (en) * 1957-09-30 1963-11-12 Congoleum Nairn Inc Urethane coating for cork surface and process therefor
US6024954A (en) * 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
WO2002077075A1 (fr) 2001-03-22 2002-10-03 Rhodia Chimie Procede de fabrication de particules colloidales de forme controlee avec des copolymeres a blocs hydrosolubles comprenant un bloc hydrophobe et un bloc hydrophile
US7879820B2 (en) * 2002-04-22 2011-02-01 L'oreal S.A. Use of a cyclodextrin as pearlescent agent and pearlescent compositions
US20090018270A1 (en) * 2003-09-03 2009-01-15 Regan Crooks Copolymer having a controlled structure and use thereof
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
DK1809345T3 (da) * 2004-10-07 2009-07-13 Coloplast As Medikoindretning med en vædet hydrofil coating
JP5182732B2 (ja) * 2007-04-17 2013-04-17 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ ヒドロゲル関節形成装置
EP2285853B1 (en) * 2008-05-13 2013-02-27 University of Washington Micellic assemblies
JP5540599B2 (ja) * 2008-10-31 2014-07-02 Ｊｓｒ株式会社 着色層形成用感放射線性組成物、カラーフィルタ及びカラー液晶表示素子
US20140051771A1 (en) * 2012-08-20 2014-02-20 Ticona Llc Biomedical Devices Comprising Molded Polyethylene Components
WO2014063102A1 (en) 2012-10-19 2014-04-24 Cornell University Biomimetic boundary lubricants for articular cartilage
CN105073155B (zh) * 2013-04-01 2018-10-19 泰尔茂株式会社 医疗器械及医疗器械的制造方法
WO2015054452A1 (en) 2013-10-11 2015-04-16 Basf Se Keratin conditioning bio-based polymers for use in personal care compositions
WO2015144886A1 (de) 2014-03-27 2015-10-01 Sika Technology Ag Blockcopolymer
US9913927B2 (en) * 2014-07-14 2018-03-13 University Of Utah Research Foundation In situ solidifying complex coacervates and methods of making and using thereof
US10646574B2 (en) * 2014-07-21 2020-05-12 Board Of Regents, The University Of Texas System Formulations of intraarticular pharmaceutical agents and methods for preparing and using the same
DK3523339T3 (da) * 2016-10-04 2025-08-25 Univ Cornell Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler

Also Published As

Publication number Publication date
PL3523339T3 (pl) 2025-12-15
CN110050003A (zh) 2019-07-23
US11376276B2 (en) 2022-07-05
US20230210892A1 (en) 2023-07-06
JP2019534922A (ja) 2019-12-05
US12364710B2 (en) 2025-07-22
CN110050003B (zh) 2022-07-22
EP3523339A1 (en) 2019-08-14
CN115386055B (zh) 2025-07-08
WO2018067648A1 (en) 2018-04-12
EP3523339A4 (en) 2020-06-03
JP7085536B2 (ja) 2022-06-16
EP3523339B1 (en) 2025-05-14
ES3039978T3 (en) 2025-10-28
CN115386055A (zh) 2022-11-25
JP2022088630A (ja) 2022-06-14
US20190231811A1 (en) 2019-08-01

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