DK3538530T3 - Opløsning af optisk aktive diazaspiro[4.5]decan-derivater - Google Patents
Opløsning af optisk aktive diazaspiro[4.5]decan-derivater Download PDFInfo
- Publication number
- DK3538530T3 DK3538530T3 DK17838138.0T DK17838138T DK3538530T3 DK 3538530 T3 DK3538530 T3 DK 3538530T3 DK 17838138 T DK17838138 T DK 17838138T DK 3538530 T3 DK3538530 T3 DK 3538530T3
- Authority
- DK
- Denmark
- Prior art keywords
- diazaspiro
- dissolution
- optically active
- decane derivatives
- decane
- Prior art date
Links
- YMANQWHUUFJQOW-UHFFFAOYSA-N 1,2-diazaspiro[4.5]decane Chemical class N1NCCC11CCCCC1 YMANQWHUUFJQOW-UHFFFAOYSA-N 0.000 title 1
- 238000004090 dissolution Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662419557P | 2016-11-09 | 2016-11-09 | |
| PCT/IB2017/001594 WO2018087602A1 (en) | 2016-11-09 | 2017-11-09 | Resolution of optically active diazaspiro[4.5]decane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3538530T3 true DK3538530T3 (da) | 2022-03-28 |
Family
ID=61163735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17838138.0T DK3538530T3 (da) | 2016-11-09 | 2017-11-09 | Opløsning af optisk aktive diazaspiro[4.5]decan-derivater |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190263815A1 (da) |
| EP (1) | EP3538530B1 (da) |
| JP (2) | JP7229917B2 (da) |
| CN (2) | CN110177790B (da) |
| AR (1) | AR110150A1 (da) |
| CA (1) | CA3043442A1 (da) |
| DK (1) | DK3538530T3 (da) |
| ES (1) | ES2911447T3 (da) |
| TW (1) | TWI762527B (da) |
| WO (1) | WO2018087602A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210102887A (ko) * | 2018-11-14 | 2021-08-20 | 알타반트 사이언시스 게엠베하 | 말초 세로토닌과 관련된 질병 또는 장애를 치료하기 위한 트립토판 하이드록실라제 1 (tph1)의 결정질 스피로사이클릭 화합물 억제제 |
| CN111621492B (zh) * | 2020-06-15 | 2021-10-26 | 安徽红杉生物医药科技有限公司 | 内酰胺酶及其应用和酶法拆分制备(1r，4s)-文斯内酯的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3682925A (en) * | 1969-01-30 | 1972-08-08 | Hoffmann La Roche | ({31 )-di-o-isopropylidene-2-keto-l-gulonates |
| US3904632A (en) * | 1972-05-08 | 1975-09-09 | Hoffmann La Roche | (')-di-o-isopropylidene-2-keto-l-gulonates |
| US4859771A (en) * | 1986-07-14 | 1989-08-22 | Merck & Co., Inc. | Process for resolution and racemization of amines with acidic α-hydrogens |
| US5030725A (en) * | 1990-02-06 | 1991-07-09 | Eli Lilly And Company | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one using (-)-DAG |
| CN1105723C (zh) | 1996-08-28 | 2003-04-16 | 普罗克特和甘保尔公司 | 螺环金属蛋白酶抑制剂 |
| DE19927412A1 (de) | 1999-06-16 | 2000-12-21 | Bayer Ag | Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0]nonan |
| EP2285769B1 (en) | 2008-06-02 | 2014-08-13 | Generics [UK] Limited | A process for the preparation of enantiomerically pure amines |
| TW201103540A (en) * | 2009-06-16 | 2011-02-01 | Ono Pharmaceutical Co | Compound having spiro-linked cyclic group and uses thereof |
| JP2014501771A (ja) * | 2011-01-07 | 2014-01-23 | ハー・ルンドベック・アクチエゼルスカベット | ４−（（１ｒ，３ｓ）−６−クロロ−３−フェニル−インダン−１−イル）−１，２，２−トリメチル−ピペラジンと１−（（１ｒ，３ｓ）−６−クロロ−３−フェニル−インダン，１−イル）−３，３−ジメチル−ピペラジンとを分割するための方法 |
| UA119247C2 (uk) | 2013-09-06 | 2019-05-27 | РОЙВЕНТ САЙЕНСИЗ ҐмбГ | Спіроциклічні сполуки як інгібітори триптофангідроксилази |
-
2017
- 2017-11-08 AR ARP170103102A patent/AR110150A1/es not_active Application Discontinuation
- 2017-11-09 CA CA3043442A patent/CA3043442A1/en active Pending
- 2017-11-09 WO PCT/IB2017/001594 patent/WO2018087602A1/en not_active Ceased
- 2017-11-09 CN CN201780069288.XA patent/CN110177790B/zh not_active Expired - Fee Related
- 2017-11-09 CN CN202211097232.4A patent/CN115536661A/zh active Pending
- 2017-11-09 DK DK17838138.0T patent/DK3538530T3/da active
- 2017-11-09 ES ES17838138T patent/ES2911447T3/es active Active
- 2017-11-09 EP EP17838138.0A patent/EP3538530B1/en active Active
- 2017-11-09 JP JP2019525887A patent/JP7229917B2/ja active Active
- 2017-11-09 TW TW106138813A patent/TWI762527B/zh not_active IP Right Cessation
-
2019
- 2019-05-09 US US16/407,375 patent/US20190263815A1/en not_active Abandoned
-
2021
- 2021-01-14 US US17/149,070 patent/US11708365B2/en active Active
-
2023
- 2023-02-15 JP JP2023021579A patent/JP2023078126A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2911447T3 (es) | 2022-05-19 |
| CN115536661A (zh) | 2022-12-30 |
| JP2023078126A (ja) | 2023-06-06 |
| CA3043442A1 (en) | 2018-05-17 |
| CN110177790A (zh) | 2019-08-27 |
| JP7229917B2 (ja) | 2023-02-28 |
| US20190263815A1 (en) | 2019-08-29 |
| US11708365B2 (en) | 2023-07-25 |
| WO2018087602A1 (en) | 2018-05-17 |
| TWI762527B (zh) | 2022-05-01 |
| EP3538530A1 (en) | 2019-09-18 |
| JP2019534313A (ja) | 2019-11-28 |
| EP3538530B1 (en) | 2022-01-05 |
| CN110177790B (zh) | 2022-10-14 |
| US20210139481A1 (en) | 2021-05-13 |
| AR110150A1 (es) | 2019-02-27 |
| TW201829409A (zh) | 2018-08-16 |
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