DK3548053T3 - Bakteriofagsammensætninger, der omfatter respiratoriske antibakterielle fager, og fremgangsmåder til anvendelse deraf - Google Patents

Bakteriofagsammensætninger, der omfatter respiratoriske antibakterielle fager, og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3548053T3
DK3548053T3 DK17838002.8T DK17838002T DK3548053T3 DK 3548053 T3 DK3548053 T3 DK 3548053T3 DK 17838002 T DK17838002 T DK 17838002T DK 3548053 T3 DK3548053 T3 DK 3548053T3
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Denmark
Prior art keywords
bacterium
subjects
methods
compositions including
subject compositions
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DK17838002.8T
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English (en)
Inventor
Leandro Clara Isabel Rodrigues
Sofia Valker Côrte-Real
Garcia Miguel Ângelo Costa
Barbosa Ana Raquel Martins
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Technophage Investig E Desenvolvimento Em Biotecnologia Sa
Tecnifar Ind Tecnica Farmaceutica S A
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Publication of DK3548053T3 publication Critical patent/DK3548053T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/40Viruses, e.g. bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00031Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00071Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
DK17838002.8T 2016-12-05 2017-12-04 Bakteriofagsammensætninger, der omfatter respiratoriske antibakterielle fager, og fremgangsmåder til anvendelse deraf DK3548053T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662430113P 2016-12-05 2016-12-05
PCT/PT2017/050028 WO2018106135A2 (en) 2016-12-05 2017-12-04 Bacteriophage compositions comprising respiratory antibacterial phages and methods of use thereof

Publications (1)

Publication Number Publication Date
DK3548053T3 true DK3548053T3 (da) 2022-05-09

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ID=61148457

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17838002.8T DK3548053T3 (da) 2016-12-05 2017-12-04 Bakteriofagsammensætninger, der omfatter respiratoriske antibakterielle fager, og fremgangsmåder til anvendelse deraf

Country Status (10)

Country Link
US (1) US11672839B2 (da)
EP (1) EP3548053B8 (da)
JP (1) JP7154543B2 (da)
CN (1) CN110691603B (da)
AU (1) AU2017371484B2 (da)
BR (1) BR112019011660A2 (da)
DK (1) DK3548053T3 (da)
ES (1) ES2912268T3 (da)
PT (1) PT3548053T (da)
WO (1) WO2018106135A2 (da)

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CA3099316A1 (en) * 2018-05-04 2019-11-07 Locus Biosciences, Inc. Methods and compositions for killing a target bacterium
US20210187046A1 (en) * 2019-12-19 2021-06-24 Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa Cocktail compositions comprising respiratory antibacterial phages and methods of use thereof
US12594312B2 (en) 2020-04-27 2026-04-07 Armata Pharmaceuticals, Inc. Bacteriophage compositions for treating Pseudomonas infection
JP7584162B2 (ja) 2020-05-22 2024-11-15 ライセンテク カンパニー リミテッド 新規なポリペプチド、融合ポリペプチド、およびこれを含むグラム陰性菌に対する抗生物質
KR102224897B1 (ko) * 2020-05-22 2021-03-08 주식회사 라이센텍 신규한 폴리펩타이드 및 이를 포함하는 그람음성균에 대한 항생제
PL434485A1 (pl) * 2020-06-26 2021-12-27 Proteon Pharmaceuticals Spółka Akcyjna Synergistyczna kompozycja fagów oraz sposób jej otrzymywania
AU2022247325A1 (en) * 2021-03-30 2023-10-05 Biomx Ltd. Pseudomonas bacteriophage and uses thereof
US20220331381A1 (en) * 2021-04-10 2022-10-20 Intron Biotechnology, Inc. Compositions and methods for inhibiting the proliferation of enterotoxigenic bacteroides fragilis
US20220323518A1 (en) * 2021-04-10 2022-10-13 Intron Biotechnology, Inc. Compositions and methods for inhibiting the proliferation of enterotoxigenic bacteroides fragilis
US20220323517A1 (en) * 2021-04-10 2022-10-13 Intron Biotechnology, Inc. Compositions and methods for inhibiting the proliferation of enterotoxigenic bacteroides fragilis
CN113025582B (zh) * 2021-05-19 2022-04-15 吉林大学 一株肺炎克雷伯菌噬菌体及医用用途
WO2023122608A1 (en) * 2021-12-21 2023-06-29 Adaptive Phage Therapeutics, Inc. Assay for matching phage to bacteria
EP4265263A1 (en) * 2022-04-19 2023-10-25 Fundacion Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz Bacteriophage suitable for treating a bacterial infection caused by pseudomonas aeruginosa
EP4265264A1 (en) * 2022-04-19 2023-10-25 Fundacion Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz Bacteriophages suitable for treating a bacterial infection caused by klebsiella pneumoniae
EP4344399A1 (en) * 2022-08-11 2024-04-03 Phagelab Chile SPA Bacteriophages and compositions thereof for controlling the growth of pseudomonas lundensis in meat products
EP4720263A1 (en) * 2023-06-01 2026-04-08 University of Florida Research Foundation, Incorporated Phage therapy utilizing a unique cocktail of pseudomonas aeruginosa phages
WO2025081186A1 (en) * 2023-10-12 2025-04-17 The Government of the United States, as represented by the Director of the Defense Health Agency Bacteriophage cocktail to target diverse lineages of multidrug-resistant klebsiella pneumoniae
WO2025101001A1 (en) * 2023-11-10 2025-05-15 Microbiotix Co., Ltd. Bacteriophage and bacteriophage cocktails and uses thereof
WO2025104708A1 (en) 2023-11-16 2025-05-22 Technophage, Investigação E Desenvolvimento Em Biotecnologia, S.A. Method for determining the susceptibility of bacteria to bacteriophages
CN117843804B (zh) * 2023-12-29 2024-08-20 北京贝来药业有限公司 单域抗体串联分子及其序列、产品、制备和应用
WO2025242868A1 (en) * 2024-05-23 2025-11-27 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Phage composition
CN121622671A (zh) * 2026-02-02 2026-03-10 山东省妇幼保健院 美罗培南或氨曲南与萘啶酸联用在制备抗菌药物中的应用

Family Cites Families (9)

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US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
DE602004031341D1 (de) * 2003-07-21 2011-03-24 Transgene Sa Multifunktionelle cytokine
US8563504B2 (en) 2008-10-10 2013-10-22 Lusomedicamenta, S.A. Antibacterial phage peptides and methods of use thereof
AU2010211456B2 (en) 2009-02-06 2016-05-26 Technophage, Investigação E Desenvolvimento Em Biotecnologia, S.A. Antibacterial phage, phage peptides and methods of use thereof
PT104837A (pt) 2009-11-24 2011-05-24 Technophage Investiga O E Desenvolvimento Em Biotecnologia S A P?ptidos de fagos enteroc?cicos e m?todos para a sua utiliza??o
EP2536406A4 (en) * 2010-02-03 2014-04-09 Microbion Corp WISMUT THIOLE AS ANTISEPTICA FOR BIOMEDICAL USE INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES
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Also Published As

Publication number Publication date
JP2020500935A (ja) 2020-01-16
CN110691603A (zh) 2020-01-14
WO2018106135A3 (en) 2018-08-16
CA3045284A1 (en) 2018-06-14
PT3548053T (pt) 2022-05-04
US20190290709A1 (en) 2019-09-26
EP3548053B1 (en) 2022-03-02
JP7154543B2 (ja) 2022-10-18
EP3548053A2 (en) 2019-10-09
ES2912268T3 (es) 2022-05-25
AU2017371484A1 (en) 2019-06-20
CN110691603B (zh) 2024-01-30
EP3548053B8 (en) 2022-04-27
BR112019011660A2 (pt) 2019-10-22
US11672839B2 (en) 2023-06-13
AU2017371484B2 (en) 2022-09-15
WO2018106135A2 (en) 2018-06-14

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