DK3676297T3 - Forbindelser, sammensætninger og fremgangsmåder - Google Patents
Forbindelser, sammensætninger og fremgangsmåder Download PDFInfo
- Publication number
- DK3676297T3 DK3676297T3 DK18850713.1T DK18850713T DK3676297T3 DK 3676297 T3 DK3676297 T3 DK 3676297T3 DK 18850713 T DK18850713 T DK 18850713T DK 3676297 T3 DK3676297 T3 DK 3676297T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- compounds
- methods
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553750P | 2017-09-01 | 2017-09-01 | |
| US201762609267P | 2017-12-21 | 2017-12-21 | |
| US201862634721P | 2018-02-23 | 2018-02-23 | |
| US201862697281P | 2018-07-12 | 2018-07-12 | |
| PCT/US2018/049197 WO2019046779A1 (en) | 2017-09-01 | 2018-08-31 | COMPOUNDS, COMPOSITIONS AND METHODS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3676297T3 true DK3676297T3 (da) | 2023-08-14 |
Family
ID=65526108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18850713.1T DK3676297T3 (da) | 2017-09-01 | 2018-08-31 | Forbindelser, sammensætninger og fremgangsmåder |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12139478B2 (da) |
| EP (2) | EP4248965A3 (da) |
| JP (3) | JP7382308B2 (da) |
| CN (1) | CN111201245B (da) |
| CA (1) | CA3072057A1 (da) |
| DK (1) | DK3676297T3 (da) |
| ES (1) | ES2952994T3 (da) |
| FI (1) | FI3676297T3 (da) |
| HU (1) | HUE062446T2 (da) |
| MA (1) | MA50063A (da) |
| PL (1) | PL3676297T3 (da) |
| PT (1) | PT3676297T (da) |
| SI (1) | SI3676297T1 (da) |
| TW (1) | TW201920129A (da) |
| WO (1) | WO2019046779A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20200054A (es) | 2017-08-09 | 2020-03-21 | Denali Therapeutics Inc | Compuestos, composiciones y métodos |
| HUE062446T2 (hu) | 2017-09-01 | 2023-11-28 | Denali Therapeutics Inc | Vegyületek, készítmények és eljárások |
| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
| AU2018383675A1 (en) | 2017-12-13 | 2020-07-09 | Altos Labs, Inc. | Inhibitors of integrated stress response pathway |
| MX2020013269A (es) | 2018-06-05 | 2021-02-18 | Praxis Biotech LLC | Inhibidores de la vía de respuesta al estrés integrada. |
| TWI771621B (zh) | 2018-10-11 | 2022-07-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| EP3923935A4 (en) | 2019-02-13 | 2022-10-26 | Denali Therapeutics Inc. | COMPOUNDS, COMPOSITIONS AND METHODS |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| CA3137212A1 (en) * | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| IL287379B2 (en) * | 2019-04-23 | 2025-11-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| PE20220572A1 (es) * | 2019-04-30 | 2022-04-20 | Calico Life Sciences Llc | Moduladores de la via integrada del estres |
| CN114466654A (zh) | 2019-06-12 | 2022-05-10 | 普拉西斯生物技术有限责任公司 | 整合应激反应通路调节剂 |
| EP4096665A1 (en) | 2020-01-28 | 2022-12-07 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| CA3165813A1 (en) * | 2020-03-11 | 2021-09-16 | Holly Victoria Atton | Modulators of the integrated stress response pathway |
| KR20230110509A (ko) * | 2020-10-22 | 2023-07-24 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| MX2023004626A (es) | 2020-10-22 | 2023-05-23 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| CN116761803A (zh) * | 2020-10-22 | 2023-09-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| AU2021363616B2 (en) * | 2020-10-22 | 2026-03-26 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| KR20230116796A (ko) * | 2020-10-30 | 2023-08-04 | 칼리코 라이프 사이언시스 엘엘씨 | 통합된 스트레스 경로의 조절인자 |
| CN117580824A (zh) * | 2020-10-30 | 2024-02-20 | 卡里科生命科学有限责任公司 | 整合应激通路的调节剂 |
| CN116768877B (zh) * | 2022-05-30 | 2026-03-31 | 中国药科大学 | Isr抑制剂及其制备方法和应用 |
| TW202440081A (zh) * | 2023-03-14 | 2024-10-16 | 美商人福醫藥美國公司 | σ-1受體拮抗劑及其應用 |
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| CR20200054A (es) | 2017-08-09 | 2020-03-21 | Denali Therapeutics Inc | Compuestos, composiciones y métodos |
| HUE062446T2 (hu) | 2017-09-01 | 2023-11-28 | Denali Therapeutics Inc | Vegyületek, készítmények és eljárások |
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| EP3704089B1 (en) | 2017-11-02 | 2023-07-19 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| CA3080948A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37957A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
| SG11202004009TA (en) | 2017-11-02 | 2020-05-28 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| WO2019090078A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| AU2018358157B2 (en) | 2017-11-02 | 2023-03-09 | Abbvie Inc. | Modulators of the integrated stress pathway |
| UY37958A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| AU2018383675A1 (en) | 2017-12-13 | 2020-07-09 | Altos Labs, Inc. | Inhibitors of integrated stress response pathway |
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| EP3820843A1 (en) | 2018-07-09 | 2021-05-19 | GlaxoSmithKline Intellectual Property Development Limited | Chemical compounds |
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| EP3923935A4 (en) | 2019-02-13 | 2022-10-26 | Denali Therapeutics Inc. | COMPOUNDS, COMPOSITIONS AND METHODS |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| WO2020181247A1 (en) | 2019-03-06 | 2020-09-10 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| IL287379B2 (en) | 2019-04-23 | 2025-11-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| PE20220572A1 (es) | 2019-04-30 | 2022-04-20 | Calico Life Sciences Llc | Moduladores de la via integrada del estres |
| EP3962899A1 (en) | 2019-04-30 | 2022-03-09 | Calico Life Sciences LLC | Substituted cyclolakyls as modulators of the integrated stress pathway |
| EP4096665A1 (en) | 2020-01-28 | 2022-12-07 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| US20240059662A1 (en) | 2020-12-18 | 2024-02-22 | Denali Therapeutics Inc. | Solid forms of a compound |
| JP2025523444A (ja) | 2022-06-23 | 2025-07-23 | デナリ セラピューティクス インコーポレイテッド | 真核生物型開始因子２ｂのモジュレーターの調製プロセス |
-
2018
- 2018-08-31 HU HUE18850713A patent/HUE062446T2/hu unknown
- 2018-08-31 FI FIEP18850713.1T patent/FI3676297T3/fi active
- 2018-08-31 ES ES18850713T patent/ES2952994T3/es active Active
- 2018-08-31 CA CA3072057A patent/CA3072057A1/en active Pending
- 2018-08-31 EP EP23173466.6A patent/EP4248965A3/en not_active Withdrawn
- 2018-08-31 SI SI201830964T patent/SI3676297T1/sl unknown
- 2018-08-31 WO PCT/US2018/049197 patent/WO2019046779A1/en not_active Ceased
- 2018-08-31 CN CN201880063335.4A patent/CN111201245B/zh active Active
- 2018-08-31 DK DK18850713.1T patent/DK3676297T3/da active
- 2018-08-31 MA MA050063A patent/MA50063A/fr unknown
- 2018-08-31 PL PL18850713.1T patent/PL3676297T3/pl unknown
- 2018-08-31 JP JP2020511347A patent/JP7382308B2/ja active Active
- 2018-08-31 US US16/643,168 patent/US12139478B2/en active Active
- 2018-08-31 EP EP18850713.1A patent/EP3676297B1/en active Active
- 2018-08-31 PT PT188507131T patent/PT3676297T/pt unknown
- 2018-08-31 TW TW107130678A patent/TW201920129A/zh unknown
-
2023
- 2023-02-28 JP JP2023030214A patent/JP2023060020A/ja active Pending
-
2024
- 2024-04-08 JP JP2024062313A patent/JP2024086819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024086819A (ja) | 2024-06-28 |
| JP2023060020A (ja) | 2023-04-27 |
| EP4248965A2 (en) | 2023-09-27 |
| US20200331900A1 (en) | 2020-10-22 |
| FI3676297T3 (fi) | 2023-08-08 |
| WO2019046779A1 (en) | 2019-03-07 |
| JP7382308B2 (ja) | 2023-11-16 |
| EP3676297A4 (en) | 2021-04-28 |
| MA50063A (fr) | 2021-04-28 |
| US12139478B2 (en) | 2024-11-12 |
| JP2020532506A (ja) | 2020-11-12 |
| SI3676297T1 (sl) | 2023-12-29 |
| HUE062446T2 (hu) | 2023-11-28 |
| EP4248965A3 (en) | 2023-11-22 |
| CN111201245B (zh) | 2024-04-05 |
| CA3072057A1 (en) | 2019-03-07 |
| EP3676297A1 (en) | 2020-07-08 |
| TW201920129A (zh) | 2019-06-01 |
| PT3676297T (pt) | 2023-08-29 |
| CN111201245A (zh) | 2020-05-26 |
| PL3676297T3 (pl) | 2023-12-11 |
| ES2952994T3 (es) | 2023-11-07 |
| EP3676297B1 (en) | 2023-05-17 |
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