DK3551631T3 - Non-peptid oxytocin-receptoragonister - Google Patents

Non-peptid oxytocin-receptoragonister Download PDF

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Publication number
DK3551631T3
DK3551631T3 DK17880082.7T DK17880082T DK3551631T3 DK 3551631 T3 DK3551631 T3 DK 3551631T3 DK 17880082 T DK17880082 T DK 17880082T DK 3551631 T3 DK3551631 T3 DK 3551631T3
Authority
DK
Denmark
Prior art keywords
receptoragonister
peptid
oxytocin
peptid oxytocin
Prior art date
Application number
DK17880082.7T
Other languages
English (en)
Inventor
Michael Kassiou
William Jorgensen
Eryn Werry
Tristan Reekie
Michael Bowen
Iain Mcgregor
Original Assignee
Kinoxis Therapeutics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016905126A external-priority patent/AU2016905126A0/en
Application filed by Kinoxis Therapeutics Pty Ltd filed Critical Kinoxis Therapeutics Pty Ltd
Application granted granted Critical
Publication of DK3551631T3 publication Critical patent/DK3551631T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DK17880082.7T 2016-12-12 2017-12-12 Non-peptid oxytocin-receptoragonister DK3551631T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016905126A AU2016905126A0 (en) 2016-12-12 Non-peptide oxytocin receptor agonists
PCT/AU2017/051371 WO2018107216A1 (en) 2016-12-12 2017-12-12 Non-peptide oxytocin receptor agonists

Publications (1)

Publication Number Publication Date
DK3551631T3 true DK3551631T3 (en) 2025-02-17

Family

ID=62557695

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17880082.7T DK3551631T3 (en) 2016-12-12 2017-12-12 Non-peptid oxytocin-receptoragonister

Country Status (19)

Country Link
US (2) US11491165B2 (da)
EP (2) EP3551631B9 (da)
JP (3) JP7089649B2 (da)
KR (1) KR102561721B1 (da)
CN (1) CN110248944A (da)
AU (1) AU2017377653B2 (da)
BR (1) BR112019012049A2 (da)
CA (1) CA3046809A1 (da)
DK (1) DK3551631T3 (da)
ES (1) ES3001195T3 (da)
FI (1) FI3551631T3 (da)
HU (1) HUE070078T2 (da)
IL (1) IL267276B2 (da)
MX (1) MX2019006942A (da)
PL (1) PL3551631T3 (da)
PT (1) PT3551631T (da)
RU (1) RU2019120162A (da)
SI (1) SI3551631T1 (da)
WO (1) WO2018107216A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020102857A1 (en) * 2018-11-23 2020-05-28 The University Of Sydney Methods for management of weight
EP4025221A4 (en) * 2019-09-06 2024-01-03 Kinoxis Therapeutics Pty Ltd TREATMENT OF OPIOID WITHDRAWAL
CA3154131A1 (en) 2019-09-13 2021-03-18 Origenis Gmbh 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as lrrk2, nuak1 and/or tyk2 kinase modulators for the treatment of e.g. autoimmune disease
MX2023006986A (es) * 2020-12-14 2023-06-26 Kinoxis Therapeutics Pty Ltd Moduladores de receptor de oxitocina.
CA3211786A1 (en) * 2021-03-18 2022-09-22 Michael Thomas Bowen Methods of treatment

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770762A (en) * 1972-08-29 1973-11-06 Parke Davis & Co Diazepine compounds and methods for their production
AR002459A1 (es) * 1995-01-17 1998-03-25 American Cyanamid Co Antagonistas de vasopresina de benzacepina triciclicos, una composicion farmaceutica que los contiene, un metodo para tratar enfermedades y unprocedimiento para su preparacion.
US5536718A (en) * 1995-01-17 1996-07-16 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
GB0115515D0 (en) * 2001-06-25 2001-08-15 Ferring Bv Oxytocin agonisys
GB0120051D0 (en) * 2001-08-16 2001-10-10 Ferring Bv Oxytocin agonists
EP1449844A1 (en) * 2003-02-14 2004-08-25 Ferring B.V. benzamide derivatives as oxytocin agonists and vasopressin antagonists
US7342112B2 (en) * 2003-07-01 2008-03-11 Ppg Industries Ohio, Inc. Photochromic compounds
EP1512687A1 (en) * 2003-09-05 2005-03-09 Ferring B.V. Piperazines as oxytocin agonists
EP1632494A1 (en) * 2004-08-24 2006-03-08 Ferring B.V. Vasopressin v1a antagonists
DK1802625T3 (da) * 2004-10-13 2008-09-01 Hoffmann La Roche Disubstituerede pyrazolobenzodiazepiner der er nyttige som inhibitorer af CDK2 og angiogenese og til behandling af bryst-, tyktarms-, lunge- og prostatacancer
CN101203516A (zh) * 2005-04-05 2008-06-18 法马科皮亚公司 用于免疫抑制的嘌呤及咪唑并吡啶衍生物
BRPI0617770A2 (pt) * 2005-10-24 2011-08-09 Wyeth Corp método de tratamento de esquizofrenia ou um transtorno relacionado à esquizofrenia, ansiedade ou um transtorno relacionado à ansiedade
WO2008103382A1 (en) * 2007-02-20 2008-08-28 Sergey Kozmin Method for assembling high-purity chemical libraries, compounds suppressing acetyl coenzyme a carboxylase activities discovered by same
GB0903493D0 (en) * 2009-02-27 2009-04-08 Vantia Ltd New compounds
EP3226689B1 (en) * 2014-12-05 2020-01-15 Merck Sharp & Dohme Corp. Novel tricyclic compounds as inhibitors of mutant idh enzymes
DK3328864T3 (da) * 2015-07-06 2022-12-05 Kinoxis Therapeutics Pty Ltd Terapeutiske forbindelser og sammensætninger til behandling af sociale forstyrrelser og stofmisbrugsforstyrrelser

Also Published As

Publication number Publication date
MX2019006942A (es) 2019-10-21
IL267276B1 (en) 2024-05-01
FI3551631T3 (fi) 2025-01-16
EP4494705A2 (en) 2025-01-22
AU2017377653A1 (en) 2019-07-11
KR20190091534A (ko) 2019-08-06
SI3551631T1 (sl) 2025-03-31
CN110248944A (zh) 2019-09-17
ES3001195T3 (es) 2025-03-04
RU2019120162A3 (da) 2021-01-28
JP2024107136A (ja) 2024-08-08
JP2022097655A (ja) 2022-06-30
HUE070078T2 (hu) 2025-05-28
RU2019120162A (ru) 2021-01-12
JP2020500924A (ja) 2020-01-16
EP3551631A4 (en) 2020-07-15
CA3046809A1 (en) 2018-06-21
JP7089649B2 (ja) 2022-06-23
IL267276A (en) 2019-08-29
NZ754890A (en) 2025-03-28
IL267276B2 (en) 2024-09-01
BR112019012049A2 (pt) 2019-11-12
EP3551631B9 (en) 2025-02-26
WO2018107216A1 (en) 2018-06-21
EP3551631B1 (en) 2024-11-13
EP4494705A3 (en) 2025-04-02
US11491165B2 (en) 2022-11-08
US20230330103A1 (en) 2023-10-19
AU2017377653B2 (en) 2022-04-21
PL3551631T3 (pl) 2025-03-24
KR102561721B1 (ko) 2023-07-28
US20200000823A1 (en) 2020-01-02
EP3551631A1 (en) 2019-10-16
PT3551631T (pt) 2024-12-10

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