DK3608425T3 - Hcbi, msbi, mssi og cmi sekvenser som en tidlig markør for den fremtidige udvikling af cancer og sygdomme i cns og som mål for behandling og forebyggelse af disse sygdom-me - Google Patents

Hcbi, msbi, mssi og cmi sekvenser som en tidlig markør for den fremtidige udvikling af cancer og sygdomme i cns og som mål for behandling og forebyggelse af disse sygdom-me Download PDF

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Publication number
DK3608425T3
DK3608425T3 DK19194614.4T DK19194614T DK3608425T3 DK 3608425 T3 DK3608425 T3 DK 3608425T3 DK 19194614 T DK19194614 T DK 19194614T DK 3608425 T3 DK3608425 T3 DK 3608425T3
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Denmark
Prior art keywords
diseases
msbi
hcbi
mssi
cmi
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DK19194614.4T
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English (en)
Inventor
Villiers-Zur Hausen Ethel-Michele De
Hausen Harald Zur
Karin Gunst
Corinna Whitley
Iranzu Lamberto Pérez
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Deutsches Krebsforsch
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
DK19194614.4T 2014-07-10 2015-07-09 Hcbi, msbi, mssi og cmi sekvenser som en tidlig markør for den fremtidige udvikling af cancer og sygdomme i cns og som mål for behandling og forebyggelse af disse sygdom-me DK3608425T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14176624.6A EP2966176A1 (en) 2014-07-10 2014-07-10 HCBI, MSBI, MSSI and CMI sequences as an early marker for the future development of cancer and diseases of the CNS and as a target for the treatment and prevention of these diseases
EP15745146.9A EP3167078B1 (en) 2014-07-10 2015-07-09 Hcbi, msbi, mssi and cmi sequences as an early marker for the future development of cancer and diseases of the cns and as a target for the treatment and prevention of these diseases

Publications (1)

Publication Number Publication Date
DK3608425T3 true DK3608425T3 (da) 2022-06-07

Family

ID=51162590

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15745146T DK3167078T3 (da) 2014-07-10 2015-07-09 HCBI-, MSBI-, MSSI- og CMI-sekvenser til en tidlig markør for fremtidig udvikling af cancer og sygdomme i CNS og som et target for behandling og forebyggelse af disse sygdomme
DK19194614.4T DK3608425T3 (da) 2014-07-10 2015-07-09 Hcbi, msbi, mssi og cmi sekvenser som en tidlig markør for den fremtidige udvikling af cancer og sygdomme i cns og som mål for behandling og forebyggelse af disse sygdom-me

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK15745146T DK3167078T3 (da) 2014-07-10 2015-07-09 HCBI-, MSBI-, MSSI- og CMI-sekvenser til en tidlig markør for fremtidig udvikling af cancer og sygdomme i CNS og som et target for behandling og forebyggelse af disse sygdomme

Country Status (8)

Country Link
US (1) US20170198018A1 (da)
EP (4) EP2966176A1 (da)
JP (2) JP2017522869A (da)
AU (2) AU2015287139B8 (da)
CA (2) CA3053822C (da)
DK (2) DK3167078T3 (da)
ES (2) ES2759436T3 (da)
WO (1) WO2016005054A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200002723A1 (en) 2014-07-10 2020-01-02 Deutsches Krebsforschungszentrum Msbi sequences as an early marker for the future development of cancer and diseases of the cns and as a target for the treatment and prevention of these diseases
EP3306316A1 (en) * 2016-10-10 2018-04-11 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Rep protein as protein antigen for use in diagnostic assays
EP3424942A1 (en) * 2017-07-07 2019-01-09 Deutsches Krebsforschungszentrum Improved rep protein for use in a diagnostic assay
EP3517960A1 (en) 2018-01-30 2019-07-31 Deutsches Krebsforschungszentrum Use of bmmf rep protein as biomarker for colon cancer
EP3653702A1 (en) * 2018-11-15 2020-05-20 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Crystal structure of a replication protein encoded by a plasmid isolated from a multiple sclerosis patient
EP3686289A1 (en) * 2019-01-24 2020-07-29 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Cmi sequences as an early marker for the future development of cancer, atherosclerosis, diabetes and diseases of the cns and as a target for the treatment and prevention of these diseases
EP3699595A1 (en) 2019-02-22 2020-08-26 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Use of bmmf1 rep protein as a biomarker for breast cancer
EP3699594A1 (en) * 2019-02-22 2020-08-26 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Use of bmmf1 rep protein as a biomarker for prostate cancer
CA3243853A1 (en) 2022-02-10 2023-08-17 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts METHOD FOR DIAGNOSING MULTIPLE SCLEROSIS
JP2025518482A (ja) 2022-05-11 2025-06-17 ドイチェス クレブスフォルシュンクスツェントルム スチフトゥング デス エッフェントリヒェン レヒツ 膵臓癌および2型糖尿病のための診断マーカーとしてのbmmf1 repタンパク質の使用
CA3252723A1 (en) 2022-05-11 2023-11-16 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts USE OF A REP PROTEIN BMMF1 AS A DIAGNOSTIC MARKER FOR LUNG CANCER

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4606918A (en) 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
ATE267877T1 (de) 1993-01-07 2004-06-15 Sequenom Inc Dns - sequenzierung durch massenspektronomie
JP3626187B2 (ja) 1993-06-07 2005-03-02 バイカル インコーポレイテッド 遺伝子治療に適するプラスミド
CA2225460A1 (en) 1995-06-23 1997-01-09 Winston Campbell Patterson Transcriptional regulation of genes encoding vascular endothelial growth factor receptors

Also Published As

Publication number Publication date
AU2015287139B8 (en) 2019-08-29
WO2016005054A8 (en) 2017-02-23
WO2016005054A3 (en) 2016-03-17
CA2954541A1 (en) 2016-01-14
US20170198018A1 (en) 2017-07-13
AU2018226469A1 (en) 2018-10-04
AU2015287139A8 (en) 2019-08-29
JP2019141042A (ja) 2019-08-29
CA3053822A1 (en) 2016-01-14
EP3167078B1 (en) 2019-09-11
EP4089183A1 (en) 2022-11-16
CA3053822C (en) 2023-01-24
AU2015287139A1 (en) 2017-02-02
AU2015287139B2 (en) 2018-09-27
WO2016005054A2 (en) 2016-01-14
EP3167078A2 (en) 2017-05-17
EP3608425B1 (en) 2022-04-13
JP2017522869A (ja) 2017-08-17
EP3608425A1 (en) 2020-02-12
AU2018226469B2 (en) 2019-12-19
EP2966176A1 (en) 2016-01-13
CA2954541C (en) 2021-05-11
DK3167078T3 (da) 2019-11-25
ES2916709T3 (es) 2022-07-05
ES2759436T3 (es) 2020-05-11

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