DK361376A - Fremgangsmade til fremstilling af antiinflammatoriske 4,5-diaryl-2-(subst.thio)imidazoler - Google Patents

Fremgangsmade til fremstilling af antiinflammatoriske 4,5-diaryl-2-(subst.thio)imidazoler

Info

Publication number: DK361376A
Authority: DK; Denmark
Prior art keywords: subst; diaryl; imidazoles; thio; inflammatory
Prior art date: 1975-08-11

Application number

DK361376A

Other languages

English (en)

Inventor

S C Cherkofsky

T R Sharpe

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-08-11

Filing date

1976-08-10

Publication date

1977-02-12

1976-08-10 Application filed by Du Pont filed Critical Du Pont

1977-02-12 Publication of DK361376A publication Critical patent/DK361376A/da

Links

SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical compound C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
230000003110 anti-inflammatory effect Effects 0.000 title 1
150000002460 imidazoles Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK361376A 1975-08-11 1976-08-10 Fremgangsmade til fremstilling af antiinflammatoriske 4,5-diaryl-2-(subst.thio)imidazoler DK361376A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US60365075A	1975-08-11	1975-08-11
US69128276A	1976-06-09	1976-06-09

Publications (1)

Publication Number	Publication Date
DK361376A true DK361376A (da)	1977-02-12

Family

ID=27084480

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK361376A DK361376A (da)	1975-08-11	1976-08-10	Fremgangsmade til fremstilling af antiinflammatoriske 4,5-diaryl-2-(subst.thio)imidazoler

Country Status (26)

Country	Link
JP (1)	JPS6011702B2 (da)
AR (2)	AR215591A1 (da)
AU (1)	AU508605B2 (da)
CA (1)	CA1074327A (da)
CH (1)	CH638791A5 (da)
DD (1)	DD126244A5 (da)
DE (1)	DE2635876A1 (da)
DK (1)	DK361376A (da)
ES (2)	ES450601A1 (da)
FI (1)	FI66177C (da)
FR (1)	FR2320745A1 (da)
GB (1)	GB1516908A (da)
GR (1)	GR61145B (da)
HU (1)	HU174707B (da)
IE (1)	IE44019B1 (da)
IL (1)	IL50230A (da)
LU (1)	LU75578A1 (da)
MX (1)	MX3932E (da)
NL (1)	NL7608915A (da)
NO (1)	NO146571C (da)
NZ (1)	NZ181731A (da)
PH (1)	PH11857A (da)
PT (1)	PT65464B (da)
SE (1)	SE428686B (da)
SU (1)	SU640662A3 (da)
YU (1)	YU198176A (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK16778A (da) *	1977-02-09	1978-08-10	Du Pont	Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) *	1977-07-07	1979-03-26	Ciba Geigy Ag	Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
DE2963572D1 (en) *	1978-04-11	1982-10-21	Ciba Geigy Ag	Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
DE2823197A1 (de) *	1978-05-24	1979-11-29	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) *	1978-08-10	1981-12-29	Ciba-Geigy Corporation	2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) *	1978-09-22	1980-02-12	Smithkline Corporation	2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) *	1979-06-08	1980-07-29	E. I. Du Pont De Nemours And Company	Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de)	1978-12-28	1980-07-17	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) *	1989-04-05	1989-05-17	May & Baker Ltd	New compositions of matter
BR9509024A (pt) *	1994-09-26	1997-09-30	Shionogi & Co	Derivados de imidazol
AU8757098A (en) *	1997-06-30	1999-02-10	Ortho-Mcneil Pharmaceutical, Inc.	2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10222103A1 (de) *	2002-05-17	2003-11-27	Merckle Gmbh Chem Pharm Fabrik	2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
RU2395499C2 (ru) *	2006-02-06	2010-07-27	Тайсо Фармасьютикал Ко., Лтд.	Ингибитор связывания сфингозин-1-фосфата

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1155580A (en) *	1965-10-21	1969-06-18	Geigy Ag J R	New Imidazole Derivatives their Production and Use
US3651080A (en) *	1969-11-07	1972-03-21	Ciba Geigy Corp	Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) *	1969-11-17	1972-01-18	Geigy Chem Corp	Substituted 2-mercaptoimidazole derivatives
US3714179A (en) *	1970-09-08	1973-01-30	Searle & Co	1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) *	1970-11-16	1972-12-26	Pfizer	Antiinflammatory imidazoles

1976
- 1976-07-02 SE SE7607615A patent/SE428686B/xx not_active IP Right Cessation
- 1976-08-05 MX MX762132U patent/MX3932E/es unknown
- 1976-08-09 DD DD194248A patent/DD126244A5/xx unknown
- 1976-08-09 CA CA258,690A patent/CA1074327A/en not_active Expired
- 1976-08-09 NO NO762754A patent/NO146571C/no unknown
- 1976-08-10 NZ NZ181737A patent/NZ181731A/xx unknown
- 1976-08-10 FI FI762290A patent/FI66177C/fi not_active IP Right Cessation
- 1976-08-10 FR FR7624400A patent/FR2320745A1/fr active Granted
- 1976-08-10 IL IL50230A patent/IL50230A/xx unknown
- 1976-08-10 SU SU762388413A patent/SU640662A3/ru active
- 1976-08-10 PH PH18773A patent/PH11857A/en unknown
- 1976-08-10 HU HU76DU252A patent/HU174707B/hu unknown
- 1976-08-10 GR GR51440A patent/GR61145B/el unknown
- 1976-08-10 GB GB33286/76A patent/GB1516908A/en not_active Expired
- 1976-08-10 PT PT65464A patent/PT65464B/pt unknown
- 1976-08-10 DK DK361376A patent/DK361376A/da not_active Application Discontinuation
- 1976-08-10 CH CH1019276A patent/CH638791A5/de not_active IP Right Cessation
- 1976-08-10 ES ES450601A patent/ES450601A1/es not_active Expired
- 1976-08-10 DE DE19762635876 patent/DE2635876A1/de not_active Withdrawn
- 1976-08-10 AU AU16711/76A patent/AU508605B2/en not_active Expired
- 1976-08-11 JP JP51094991A patent/JPS6011702B2/ja not_active Expired
- 1976-08-11 NL NL7608915A patent/NL7608915A/xx not_active Application Discontinuation
- 1976-08-11 IE IE1775/76A patent/IE44019B1/en unknown
- 1976-08-11 LU LU75578A patent/LU75578A1/xx unknown
- 1976-08-11 AR AR264308A patent/AR215591A1/es active
- 1976-08-11 YU YU01981/76A patent/YU198176A/xx unknown
1977
- 1977-07-28 ES ES461193A patent/ES461193A1/es not_active Expired
1978
- 1978-01-10 AR AR270672A patent/AR218054A1/es active

Also Published As

Publication number	Publication date
FR2320745B1 (da)	1978-12-22
FI66177C (fi)	1984-09-10
NZ181731A (en)	1978-11-13
LU75578A1 (da)	1978-04-13
CH638791A5 (de)	1983-10-14
SE7607615L (sv)	1977-02-12
IE44019L (en)	1977-02-11
SE428686B (sv)	1983-07-18
DD126244A5 (da)	1977-07-06
AU508605B2 (en)	1980-03-27
FI762290A7 (da)	1977-02-12
JPS5223076A (en)	1977-02-21
YU198176A (en)	1982-10-31
AR218054A1 (es)	1980-05-15
ES461193A1 (es)	1978-12-01
IL50230A0 (en)	1976-10-31
PT65464A (en)	1976-09-01
FI66177B (fi)	1984-05-31
HU174707B (hu)	1980-03-28
ES450601A1 (es)	1978-01-16
FR2320745A1 (fr)	1977-03-11
DE2635876A1 (de)	1977-03-03
PH11857A (en)	1978-08-03
AU1671176A (en)	1978-02-16
NL7608915A (nl)	1977-02-15
GR61145B (en)	1978-09-27
PT65464B (en)	1978-08-02
CA1074327A (en)	1980-03-25
IL50230A (en)	1979-07-25
AR215591A1 (es)	1979-10-31
SU640662A3 (ru)	1978-12-30
MX3932E (es)	1981-10-02
NO146571C (no)	1982-10-27
NO146571B (no)	1982-07-19
IE44019B1 (en)	1981-07-29
NO762754L (da)	1977-02-14
JPS6011702B2 (ja)	1985-03-27
GB1516908A (en)	1978-07-05

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Legal Events

Date	Code	Title	Description
1989-04-17	AHB	Application shelved due to non-payment