DK3622268T3 - System og indretning til analyse af specifikt stof i flydende prøver med optisk mikroskopi - Google Patents

System og indretning til analyse af specifikt stof i flydende prøver med optisk mikroskopi Download PDF

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Publication number
DK3622268T3
DK3622268T3 DK18728525.9T DK18728525T DK3622268T3 DK 3622268 T3 DK3622268 T3 DK 3622268T3 DK 18728525 T DK18728525 T DK 18728525T DK 3622268 T3 DK3622268 T3 DK 3622268T3
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DK
Denmark
Prior art keywords
analysis
optical microscopy
liquid samples
specific substance
substance
Prior art date
Application number
DK18728525.9T
Other languages
Danish (da)
English (en)
Inventor
Waal Theo De
Roohollah Ebrahimi
Michael Krivoruchko
Vladimir Lobaskin
Trish Mcowan
William O'connor
Dimitri Scholz
Original Assignee
Univ College Dublin National Univ Of Ireland
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Publication of DK3622268T3 publication Critical patent/DK3622268T3/da

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using Bluetooth®
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/019—Biological contaminants; Fouling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1488—Methods for deciding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK18728525.9T 2017-05-12 2018-05-11 System og indretning til analyse af specifikt stof i flydende prøver med optisk mikroskopi DK3622268T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17170902.5A EP3401665A1 (fr) 2017-05-12 2017-05-12 Système et dispositif d'analyse d'une substance spécifique dans des échantillons liquides par microscopie optique
PCT/EP2018/062265 WO2018206802A1 (fr) 2017-05-12 2018-05-11 Système et dispositif

Publications (1)

Publication Number Publication Date
DK3622268T3 true DK3622268T3 (da) 2022-09-19

Family

ID=58707419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18728525.9T DK3622268T3 (da) 2017-05-12 2018-05-11 System og indretning til analyse af specifikt stof i flydende prøver med optisk mikroskopi

Country Status (10)

Country Link
US (1) US12370542B2 (fr)
EP (2) EP3401665A1 (fr)
JP (1) JP7208922B2 (fr)
CN (1) CN110753837B (fr)
AU (1) AU2018265597B2 (fr)
DK (1) DK3622268T3 (fr)
ES (1) ES2928200T3 (fr)
HU (1) HUE060044T2 (fr)
PL (1) PL3622268T3 (fr)
WO (1) WO2018206802A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201820327D0 (en) * 2018-12-13 2019-01-30 Dublin Institute Of Tech On-site detection of parasitic infection of mammals
CN110108604B (zh) * 2019-05-17 2024-06-14 成都信息工程大学 基于显微放大和视角传感的高空微粒辨识装置及方法
GB202006458D0 (en) * 2020-05-01 2020-06-17 Micron Agritech Ltd A faecal egg counting slide
GB202106375D0 (en) * 2021-05-04 2021-06-16 Micron Agritech Ltd A mobile slide imaging kit and use thereof
WO2023039030A1 (fr) * 2021-09-13 2023-03-16 Applied Materials, Inc. Conceptions de cellules d'écoulement pour imagerie biologique

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0272860A (ja) * 1988-09-09 1990-03-13 Hitachi Ltd 生細胞レーザ照射装置
US5900130A (en) 1997-06-18 1999-05-04 Alcara Biosciences, Inc. Method for sample injection in microchannel device
JP2002372865A (ja) * 2001-06-15 2002-12-26 Canon Inc 現像装置及び画像形成装置
US6773677B2 (en) * 2002-01-09 2004-08-10 Caliper Life Sciences, Inc. Slide cassette for fluidic injection
CN2569131Y (zh) * 2002-09-28 2003-08-27 国家海洋技术中心 海水藻类和悬浮物浓度测量仪
BRPI0415516A (pt) 2003-10-17 2006-12-26 Biopath Automation Llc cassetes de fixação e orientação de amostras de tecidos
JP4679847B2 (ja) * 2004-07-12 2011-05-11 オリンパス株式会社 細胞の解析方法
JP2006058112A (ja) 2004-08-19 2006-03-02 Kawamura Inst Of Chem Res 微量試料計量デバイス、微量試料計量装置及び微量試料の計量方法
ATE500895T1 (de) * 2005-07-05 2011-03-15 Ibidi Gmbh Mikrofluid-vorrichtung und verfahren zur erzeugung diffusiv aufgebauter gradienten
JP2007215472A (ja) * 2006-02-16 2007-08-30 Olympus Corp 細胞培養容器
KR100790881B1 (ko) * 2006-07-06 2008-01-02 삼성전자주식회사 미세유체 반응칩 및 이의 제조방법
GB0614297D0 (en) * 2006-07-19 2006-08-30 Shaw Water Engineering Ltd Apparatus, system and method for detecting particles
CN101165472B (zh) * 2006-10-20 2010-05-12 中国科学院大连化学物理研究所 一种多通道模式毛细管电泳装置
DE102007052281A1 (de) * 2007-11-02 2009-05-07 Zenteris Gmbh Einschritt-Multiplex-Immuntest
US8961907B2 (en) 2009-07-28 2015-02-24 Menixis Limited Apparatus for the detection and analysis of particles in fluids
JP6265508B2 (ja) 2012-09-21 2018-01-24 マサチューセッツ インスティテュート オブ テクノロジー マイクロ流体装置およびその使用
CN104837560B (zh) * 2012-12-13 2017-03-22 皇家飞利浦有限公司 用于制备生物样品的盒和装置
WO2015116990A1 (fr) * 2014-01-30 2015-08-06 The General Hospital Corporation Focalisation inertio-élastique de particules dans des microcanaux
SG10201808874XA (en) * 2014-04-09 2018-11-29 Agency Science Tech & Res Microfluidic device
EP3020480B1 (fr) 2014-11-14 2019-10-02 ibidi GmbH Conduite de fluide destiné à l'examen de cellules
CN205103137U (zh) * 2015-11-18 2016-03-23 海南益世康宁生物科技有限公司 一种细胞检测仪
EP3175921A1 (fr) * 2015-12-04 2017-06-07 Consejo Superior De Investigaciones Científicas Dispositifs biophotoniques et procédés de leur utilisation
US9962701B2 (en) * 2015-12-28 2018-05-08 Qiagen Sciences, Llc Flowcells with microretainers and particle separators for discrete seeding microspots

Also Published As

Publication number Publication date
JP7208922B2 (ja) 2023-01-19
CA3099171A1 (fr) 2018-11-15
EP3622268A1 (fr) 2020-03-18
AU2018265597B2 (en) 2024-01-04
AU2018265597A1 (en) 2020-01-16
BR112019023864A2 (pt) 2020-06-02
CN110753837B (zh) 2023-02-17
WO2018206802A1 (fr) 2018-11-15
CN110753837A (zh) 2020-02-04
RU2019139512A (ru) 2021-06-15
US12370542B2 (en) 2025-07-29
EP3401665A1 (fr) 2018-11-14
RU2019139512A3 (fr) 2021-09-24
ES2928200T3 (es) 2022-11-16
HUE060044T2 (hu) 2023-01-28
JP2020519899A (ja) 2020-07-02
US20200197926A1 (en) 2020-06-25
EP3622268B1 (fr) 2022-07-06
PL3622268T3 (pl) 2022-12-05

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