DK362585D0 - Nye derivater af guanin - Google Patents

Nye derivater af guanin

Info

Publication number: DK362585D0
Authority: DK; Denmark
Prior art keywords: guanine; new derivatives; derivatives; new
Prior art date: 1983-12-20

Application number

DK362585A

Other languages

English (en)

Other versions

DK159683B (da

DK159683C (da

DK362585A (da

Inventor

Karl Nils-Gunnar Johansson

Bjoern Gunnar Lindborg

Jan-Olof Noren

Original Assignee

Astra Laekemedel Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-20

Filing date

1985-08-09

Publication date

1985-08-09

1983-12-20 Priority claimed from SE8307052A external-priority patent/SE8307052D0/xx

1983-12-20 Priority claimed from SE8307051A external-priority patent/SE8307051D0/xx

1985-08-09 Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab

1985-08-09 Publication of DK362585D0 publication Critical patent/DK362585D0/da

1985-08-09 Publication of DK362585A publication Critical patent/DK362585A/da

1990-11-19 Publication of DK159683B publication Critical patent/DK159683B/da

1991-04-15 Application granted granted Critical

1991-04-15 Publication of DK159683C publication Critical patent/DK159683C/da

Links

UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical class O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
- C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1787—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings and having unsaturation outside the aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Leads Or Probes (AREA)
Testing Of Short-Circuits, Discontinuities, Leakage, Or Incorrect Line Connections (AREA)
Tests Of Electronic Circuits (AREA)

DK362585A 1983-12-20 1985-08-09 9-(4-hydroxybutyl)-guaninderivat, farmaceutisk praeparat indeholdende en saadan forbindelse og anvendelse af den til fremstilling af et laegemiddel DK159683C (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
SE8307052A SE8307052D0 (sv)	1983-12-20	1983-12-20	Novel derivatives of guanine novel derivatives of guanine
SE8307051		1983-12-20
SE8307052		1983-12-20
SE8307051A SE8307051D0 (sv)	1983-12-20	1983-12-20	Novel derivatives of alkyl guanine novel derivatives of alkyl guanine
SE8400426		1984-12-13
PCT/SE1984/000426 WO1985002845A1 (en)	1983-12-20	1984-12-13	Novel derivatives of guanine

Publications (4)

Publication Number	Publication Date
DK362585D0 true DK362585D0 (da)	1985-08-09
DK362585A DK362585A (da)	1985-08-09
DK159683B DK159683B (da)	1990-11-19
DK159683C DK159683C (da)	1991-04-15

Family

ID=26658599

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK362585A DK159683C (da)	1983-12-20	1985-08-09	9-(4-hydroxybutyl)-guaninderivat, farmaceutisk praeparat indeholdende en saadan forbindelse og anvendelse af den til fremstilling af et laegemiddel

Country Status (20)

Country	Link
US (1)	US4798833A (da)
EP (2)	EP0165289B1 (da)
JP (1)	JPH0667939B2 (da)
KR (1)	KR910010048B1 (da)
AU (1)	AU586415B2 (da)
CA (1)	CA1285560C (da)
DE (1)	DE3477568D1 (da)
DK (1)	DK159683C (da)
ES (3)	ES8609325A1 (da)
FI (1)	FI80885C (da)
GB (1)	GB2151622B (da)
GR (1)	GR82499B (da)
HU (1)	HU193595B (da)
IE (1)	IE57913B1 (da)
IL (1)	IL73682A (da)
IS (1)	IS1507B (da)
MY (1)	MY102565A (da)
PH (1)	PH21410A (da)
PT (1)	PT79714B (da)
WO (1)	WO1985002845A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5684153A (en)	1984-08-16	1997-11-04	Beecham Group Plc	Process for the preparation of purine derivatives
EP0141927B1 (en) *	1983-08-18	1991-10-30	Beecham Group Plc	Antiviral guanine derivatives
CA1288098C (en) *	1984-08-24	1991-08-27	Richard L. Tolman	4-(guanin-9-yl)butanals and their 3-oxa, 3-thia and 2-ene derivatives having antiviral and antitumor activity
SE8406538D0 (sv) *	1984-12-21	1984-12-21	Astra Laekemedel Ab	Novel derivatives of purine
EP0216459B1 (en) *	1985-07-27	1990-05-16	Beecham Group Plc	9-substituted guanine monohydrates
EP0219838A3 (en) *	1985-10-22	1988-04-06	Takeda Chemical Industries, Ltd.	Carbocyclic purine nucleosides, their production and use
US5066655A (en) *	1987-04-24	1991-11-19	Whitby Research, Inc.	N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5565566A (en) *	1987-04-24	1996-10-15	Discovery Therapeutics, Inc.	N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5175288A (en) *	1987-08-01	1992-12-29	Beecham Group P.L.C.	Process for preparing purine derivatives and intermediates thereof
US4935427A (en) *	1987-12-31	1990-06-19	The United States Of America As Represented By The Department Of Health And Human Services	Pyrimidine and purine 1,2-butadiene-4-ols as anti-retroviral agents
SE8801729D0 (sv) *	1988-05-06	1988-05-06	Astra Ab	Purine derivatives for use in therapy
US5284837A (en) *	1988-05-06	1994-02-08	Medivir Ab	Derivatives of purine, process for their preparation and a pharmaceutical preparation
GB8817607D0 (en) *	1988-07-23	1988-09-01	Beecham Group Plc	Novel process
GB8822236D0 (en) *	1988-09-21	1988-10-26	Beecham Group Plc	Chemical process
CA2009109A1 (en) *	1989-02-02	1990-08-02	John Hannah	Antiviral acyclonucleosides and acyclonucleotides
GB8904855D0 (en) *	1989-03-03	1989-04-12	Beecham Group Plc	Pharmaceutical treatment
GB8917959D0 (en) *	1989-08-05	1989-09-20	Beecham Group Plc	Pharmaceutical formulation
GB8922076D0 (en) *	1989-09-28	1989-11-15	Beecham Group Plc	Novel process
GB9001886D0 (en) *	1990-01-26	1990-03-28	Beecham Group Plc	Pharmaceutical formulation
US5674869A (en) *	1990-07-07	1997-10-07	Beecham Group Plc	Pharmaceutical treatment
AU679763B2 (en) *	1993-06-23	1997-07-10	Merrell Pharmaceuticals Inc.	Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents
US5869493A (en) *	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
GB9615276D0 (en) *	1996-07-20	1996-09-04	Smithkline Beecham Plc	Pharmaceuticals
PT102030B (pt) *	1996-07-20	1999-04-30	Smithkline Beecham Plc	Processo para a apreparacao dos compostos penciclovir ou famciclovir que sao utesi como agentes antivirais
GB9615253D0 (en) *	1996-07-20	1996-09-04	Smithkline Beecham Plc	Pharmaceuticals
GB9807114D0 (en)	1998-04-02	1998-06-03	Smithkline Beecham Plc	Novel process
WO2021209563A1 (en)	2020-04-16	2021-10-21	Som Innovation Biotech, S.A.	Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4347360A (en) *	1980-09-16	1982-08-31	Ens Bio Logicals Inc.	Ring open nucleoside analogues
IL64501A (en) *	1980-12-22	1985-07-31	Astra Laekemedel Ab	9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use
US4355032B2 (en) *	1981-05-21	1990-10-30		9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
HU189609B (en) *	1981-08-11	1986-07-28	The Wellcome Foundation Ltd,Us	Process for production of new purin derivatives with antivirus effect and medical preparatives containing thereof as reagent
NZ201662A (en) *	1981-08-26	1986-07-11	Merck & Co Inc	9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
AU564576B2 (en) *	1981-09-24	1987-08-20	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Purine derivatives
US5250535A (en) *	1982-02-01	1993-10-05	Syntex Inc.	Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
SE8203855D0 (sv) *	1982-06-21	1982-06-21	Astra Laekemedel Ab	Novel derivatives of guanine i
SE8203856D0 (sv) *	1982-06-21	1982-06-21	Astra Laekemedel Ab	Novel derivatives of guanine ii
EP0141927B1 (en) *	1983-08-18	1991-10-30	Beecham Group Plc	Antiviral guanine derivatives
EP0216459B1 (en) *	1985-07-27	1990-05-16	Beecham Group Plc	9-substituted guanine monohydrates

1984
- 1984-11-29 IL IL73682A patent/IL73682A/xx not_active IP Right Cessation
- 1984-12-13 EP EP85900247A patent/EP0165289B1/en not_active Expired
- 1984-12-13 JP JP60500231A patent/JPH0667939B2/ja not_active Expired - Lifetime
- 1984-12-13 KR KR1019850700161A patent/KR910010048B1/ko not_active Expired
- 1984-12-13 EP EP84850390A patent/EP0146516A3/en active Pending
- 1984-12-13 WO PCT/SE1984/000426 patent/WO1985002845A1/en not_active Ceased
- 1984-12-13 AU AU37873/85A patent/AU586415B2/en not_active Expired
- 1984-12-13 HU HU84807A patent/HU193595B/hu unknown
- 1984-12-13 DE DE8585900247T patent/DE3477568D1/de not_active Expired
- 1984-12-17 PH PH31589A patent/PH21410A/en unknown
- 1984-12-18 GB GB08431910A patent/GB2151622B/en not_active Expired
- 1984-12-18 GR GR82499A patent/GR82499B/el unknown
- 1984-12-18 ES ES538721A patent/ES8609325A1/es not_active Expired
- 1984-12-19 PT PT79714A patent/PT79714B/pt unknown
- 1984-12-19 CA CA000470490A patent/CA1285560C/en not_active Expired - Lifetime
- 1984-12-19 IS IS2966A patent/IS1507B/is unknown
- 1984-12-19 IE IE3261/845A patent/IE57913B1/en not_active IP Right Cessation
1985
- 1985-08-09 DK DK362585A patent/DK159683C/da not_active IP Right Cessation
- 1985-08-19 FI FI853171A patent/FI80885C/fi active IP Right Grant
- 1985-09-12 ES ES546916A patent/ES8704170A1/es not_active Expired
1986
- 1986-04-30 ES ES554546A patent/ES8800946A1/es not_active Expired
1987
- 1987-02-06 US US07/015,481 patent/US4798833A/en not_active Expired - Lifetime
- 1987-10-01 MY MYPI87002765A patent/MY102565A/en unknown

Also Published As

Publication number	Publication date
ES554546A0 (es)	1987-12-01
AU586415B2 (en)	1989-07-13
KR850700136A (ko)	1985-10-25
FI853171A0 (fi)	1985-08-19
JPH0667939B2 (ja)	1994-08-31
HUT37619A (en)	1986-01-23
DK159683B (da)	1990-11-19
PT79714A (en)	1985-01-01
US4798833A (en)	1989-01-17
IL73682A0 (en)	1985-02-28
DE3477568D1 (en)	1989-05-11
AU3787385A (en)	1985-07-12
PH21410A (en)	1987-10-15
EP0165289B1 (en)	1989-04-05
GR82499B (en)	1985-04-19
EP0165289A1 (en)	1985-12-27
IE843261L (en)	1985-06-20
JPS61500730A (ja)	1986-04-17
MY102565A (en)	1992-07-31
IS1507B (is)	1992-09-29
ES8704170A1 (es)	1987-03-16
ES8800946A1 (es)	1987-12-01
WO1985002845A1 (en)	1985-07-04
ES546916A0 (es)	1987-03-16
GB2151622A (en)	1985-07-24
PT79714B (en)	1986-12-30
FI80885B (fi)	1990-04-30
EP0146516A2 (en)	1985-06-26
ES8609325A1 (es)	1986-09-01
IE57913B1 (en)	1993-05-19
HU193595B (en)	1987-11-30
DK159683C (da)	1991-04-15
FI853171L (fi)	1985-08-19
EP0146516A3 (en)	1985-08-14
ES538721A0 (es)	1986-09-01
CA1285560C (en)	1991-07-02
GB2151622B (en)	1988-05-11
IL73682A (en)	1991-08-16
DK362585A (da)	1985-08-09
KR910010048B1 (ko)	1991-12-12
GB8431910D0 (en)	1985-01-30
FI80885C (fi)	1990-08-10
IS2966A7 (is)	1985-06-21

Legal Events

Date	Code	Title	Description
2005-01-03	PUP	Patent expired

Publication	Publication Date	Title
IS1507B (is)	1992-09-29	Nyjar aukaafurthir af guanine
DOP1981004105A (es)	1988-04-05	Nuevos derivados de n-arilbenzamida
DK148281A (da)	1981-10-03	Substituerede acylderivater af octahydro-2h-indol-2-carboxylsyrer
DK205284D0 (da)	1984-04-24	Kompleksforbindelser af technetium-9m med alkylenaminoximer
DK344485A (da)	1986-02-01	Anvendelse af chromanderivater
DK344585A (da)	1986-02-01	Anvendelse af chromanderivater
DK486686A (da)	1987-04-13	Anvendelse af benzamidderivater
DE3166114D1 (de)	1984-10-25	N-omega substituted derivatives of 1-desamino-vasopressin analogs
ES524096A0 (es)	1984-10-01	Nuevos derivados de 19-tioandrostano
DOP1981003010A (es)	1986-10-23	Nuevos derivados de isoxazolilimidazolidinona
DK306284A (da)	1984-12-25	Substituerede phenylsulfonylguanidin-derivater
DK454085D0 (da)	1985-10-04	Monotertiaeralkylderivater af toluendiamin
ES537338A0 (es)	1986-01-01	Derivados de pirazol-piridina
DK38593A (da)	1993-03-31	Alkoxymethylethere af glyceroler
DK104389D0 (da)	1989-03-03	Anvendelse af imidazolderivater
DK316589D0 (da)	1989-06-26	Substituerede azacyclohexylderivater af rifamyciner
DK407584D0 (da)	1984-08-24	Phenylethylaminderivater
NO844072L (no)	1985-04-15	Fremgangsmaate for fremstilling av nye aminopropanonforbindelser
DK190479A (da)	1979-11-13	Derivater af n-cyano-azomethiner
NO853127L (no)	1985-08-07	Nye derivater av guanin
IT1178768B (it)	1987-09-16	Derivati di pirazolo piridina
SE8307052D0 (sv)	1983-12-20	Novel derivatives of guanine novel derivatives of guanine
DK7485A (da)	1985-01-07	Aziridinoderivater af tetramere cyclophosphazener
SE8205959D0 (sv)	1982-10-20	Novel derivatives of guanine
DK225384A (da)	1984-11-10	Bis-alkylphosphoniumsalte af n-phosphonomethylglycin