DK362689D0 - Hidtil ukendt fremgangsmaade - Google Patents

Hidtil ukendt fremgangsmaade

Info

Publication number
DK362689D0
DK362689D0 DK362689A DK362689A DK362689D0 DK 362689 D0 DK362689 D0 DK 362689D0 DK 362689 A DK362689 A DK 362689A DK 362689 A DK362689 A DK 362689A DK 362689 D0 DK362689 D0 DK 362689D0
Authority
DK
Denmark
Prior art keywords
acyloxymethyl
hydroxymethyl
hydrogen
converting
group
Prior art date
Application number
DK362689A
Other languages
English (en)
Other versions
DK362689A (da
DK171991B1 (da
Inventor
Trevor John Grinter
Peter Markham Kincey
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK362689D0 publication Critical patent/DK362689D0/da
Publication of DK362689A publication Critical patent/DK362689A/da
Application granted granted Critical
Publication of DK171991B1 publication Critical patent/DK171991B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/14—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with two methyl radicals in positions 1 and 3 and two methyl radicals in positions 7, 8, or 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Mechanical Operated Clutches (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK362689A 1988-07-23 1989-07-21 Fremgangsmåde til fremstilling af 9-(4-hydroxymethylbut-1-yl)-puriner, samt 6,9-disubstituerede 2-aminopuriner, der kan indgå i fremgangsmåden DK171991B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888817607A GB8817607D0 (en) 1988-07-23 1988-07-23 Novel process
GB8817607 1988-07-23

Publications (3)

Publication Number Publication Date
DK362689D0 true DK362689D0 (da) 1989-07-21
DK362689A DK362689A (da) 1990-01-24
DK171991B1 DK171991B1 (da) 1997-09-08

Family

ID=10641009

Family Applications (1)

Application Number Title Priority Date Filing Date
DK362689A DK171991B1 (da) 1988-07-23 1989-07-21 Fremgangsmåde til fremstilling af 9-(4-hydroxymethylbut-1-yl)-puriner, samt 6,9-disubstituerede 2-aminopuriner, der kan indgå i fremgangsmåden

Country Status (18)

Country Link
US (1) US5017701A (da)
EP (1) EP0352953B1 (da)
JP (1) JP2856773B2 (da)
KR (1) KR0137468B1 (da)
AT (1) ATE198479T1 (da)
AU (1) AU623667B2 (da)
DE (1) DE68929277T2 (da)
DK (1) DK171991B1 (da)
ES (1) ES2153343T3 (da)
FI (1) FI893535A7 (da)
GB (1) GB8817607D0 (da)
HU (1) HU204829B (da)
MA (1) MA21601A1 (da)
NO (1) NO169008C (da)
NZ (1) NZ230026A (da)
PL (1) PL161207B1 (da)
PT (1) PT91247B (da)
ZA (1) ZA895567B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
DE4020481A1 (de) * 1990-06-27 1992-01-02 Hoechst Ag Verfahren zur herstellung von substituierten acyclischen nukleosiden und dabei auftretende zwischenprodukte
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
US5874578A (en) * 1992-07-13 1999-02-23 Bristol-Myers Squibb Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
JP3241994B2 (ja) * 1995-07-03 2001-12-25 株式会社荏原製作所 水中モータ及び防水コネクタ
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
AT412211B (de) * 1996-07-20 2004-11-25 Novartis Int Pharm Ltd Verfahren zur herstellung von penciclovir und famciclovir
GB9615275D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
EP0827960A1 (en) * 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Process for producing purine derivatives
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807114D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
EP1352910A1 (en) * 2002-04-10 2003-10-15 Grünenthal GmbH New analogs of nitrobenzylthioinosine
EP1532151A2 (en) 2002-08-26 2005-05-25 Teva Pharmaceutical Industries Limited Crystalline solid famciclovir forms i, ii, iii and preparation thereof
WO2005039506A2 (en) * 2003-10-24 2005-05-06 Exelixis, Inc. P70s6 kinase modulators and method of use
KR20080091298A (ko) * 2004-05-18 2008-10-09 테바 파마슈티컬 인더스트리즈 리미티드 결정성 고체 팜시클로버의 제조를 위한 건조방법
ATE374202T1 (de) * 2004-06-29 2007-10-15 Gruenenthal Gmbh Neue analoga von nitrobenzylthioinosin
KR100618232B1 (ko) * 2004-09-22 2006-09-04 한미약품 주식회사 팜시클로버의 제조방법
GB2426247A (en) 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347185A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
US4347187A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
AU577303B2 (en) * 1983-08-18 1988-09-22 Novartis International Pharmaceutical Ltd 9-substituted-2-amino purines
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4845084A (en) * 1984-01-26 1989-07-04 Merck & Co., Inc. Phosphate derivatives of substituted butyl guanines, antiviral compositions containing them, and methods of treating viral infections with them
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
EP0302644B1 (en) * 1987-08-01 1997-01-29 Beecham Group Plc Purine compounds and their preparation
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process

Also Published As

Publication number Publication date
HU204829B (en) 1992-02-28
EP0352953B1 (en) 2001-01-03
DE68929277D1 (de) 2001-02-08
EP0352953A2 (en) 1990-01-31
NO169008B (no) 1992-01-20
JP2856773B2 (ja) 1999-02-10
DK362689A (da) 1990-01-24
KR0137468B1 (ko) 1998-06-01
ATE198479T1 (de) 2001-01-15
DE68929277T2 (de) 2001-08-23
MA21601A1 (fr) 1990-04-01
AU623667B2 (en) 1992-05-21
AU3882289A (en) 1990-01-25
FI893535A7 (fi) 1990-01-24
DK171991B1 (da) 1997-09-08
PT91247A (pt) 1990-02-08
HUT50820A (en) 1990-03-28
NO892998L (no) 1990-01-24
NO892998D0 (no) 1989-07-21
FI893535A0 (fi) 1989-07-21
EP0352953A3 (en) 1991-10-23
GB8817607D0 (en) 1988-09-01
PL161207B1 (en) 1993-06-30
NO169008C (no) 1992-04-29
JPH0259583A (ja) 1990-02-28
KR910002856A (ko) 1991-02-26
NZ230026A (en) 1992-11-25
PT91247B (pt) 1995-05-04
ZA895567B (en) 1990-07-25
ES2153343T3 (es) 2001-03-01
HK1012355A1 (en) 1999-07-30
US5017701A (en) 1991-05-21

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Legal Events

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