DK3638807T3 - MIRNA-574-5p som biomarkør til stratificering af prostaglandin E-afhængige tumorer - Google Patents

MIRNA-574-5p som biomarkør til stratificering af prostaglandin E-afhængige tumorer Download PDF

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Publication number
DK3638807T3
DK3638807T3 DK18728664.6T DK18728664T DK3638807T3 DK 3638807 T3 DK3638807 T3 DK 3638807T3 DK 18728664 T DK18728664 T DK 18728664T DK 3638807 T3 DK3638807 T3 DK 3638807T3
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Prior art keywords
mirna
prostaglandin
biomarker
stratification
dependent tumors
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DK18728664.6T
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English (en)
Inventor
Dieter Steinhilber
Meike Julia Saul
Beatrix Suess
Isabell Baumann
Per-Johan Jakobsson
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Fraunhofer Ges Forschung
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK18728664.6T 2017-06-12 2018-06-11 MIRNA-574-5p som biomarkør til stratificering af prostaglandin E-afhængige tumorer DK3638807T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17175535 2017-06-12
PCT/EP2018/065318 WO2018228978A1 (en) 2017-06-12 2018-06-11 Mirna-574-5p as a biomarker for stratification of prostaglandin e-dependent tumors

Publications (1)

Publication Number Publication Date
DK3638807T3 true DK3638807T3 (da) 2022-06-27

Family

ID=59054023

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18728664.6T DK3638807T3 (da) 2017-06-12 2018-06-11 MIRNA-574-5p som biomarkør til stratificering af prostaglandin E-afhængige tumorer

Country Status (9)

Country Link
US (1) US20200123620A1 (da)
EP (1) EP3638807B1 (da)
JP (1) JP7171712B2 (da)
KR (1) KR102726586B1 (da)
CN (1) CN110785500A (da)
CA (1) CA3067069C (da)
DK (1) DK3638807T3 (da)
ES (1) ES2911253T3 (da)
WO (1) WO2018228978A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113376386B (zh) * 2020-03-09 2025-09-02 中国科学院广州生物医药与健康研究院 一种病毒性肺炎的标志物及其应用
WO2023152568A2 (en) * 2022-02-10 2023-08-17 Oslo Universitetssykehus Hf Compositions and methods for characterizing lung cancer
EP4613860A1 (en) * 2024-03-07 2025-09-10 Technische Universität Darmstadt Inhibitors of mir-574-5p for use in intra-articular treatment of osteoarthritis and other related arthritic diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2692973A1 (en) * 2007-07-12 2009-01-15 Tragara Pharmaceuticals, Inc. Patient selection and therapeutic methods using markers of prostaglandin metabolism
CA2800557A1 (en) * 2010-04-29 2011-11-03 Medical Prognosis Institute A/S Methods and devices for predicting treatment efficacy
WO2011146937A1 (en) * 2010-05-21 2011-11-24 The Translational Genomics Research Institute Methods and kits useful in diagnosing nsclc
WO2013082624A2 (en) * 2011-12-01 2013-06-06 The Ohio State University Materials and methods related to nsaid chemoprevention in colorectal cancer
TWI568722B (zh) * 2012-06-15 2017-02-01 葛蘭馬克製藥公司 作爲mPGES-1抑制劑之三唑酮化合物

Also Published As

Publication number Publication date
EP3638807A1 (en) 2020-04-22
WO2018228978A1 (en) 2018-12-20
EP3638807B1 (en) 2022-03-30
CN110785500A (zh) 2020-02-11
CA3067069C (en) 2023-04-04
ES2911253T3 (es) 2022-05-18
JP7171712B2 (ja) 2022-11-15
JP2020523039A (ja) 2020-08-06
CA3067069A1 (en) 2018-12-20
US20200123620A1 (en) 2020-04-23
KR102726586B1 (ko) 2024-11-05
KR20200018508A (ko) 2020-02-19

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