DK365484D0 - Fremgangsmaade til fremstilling af polypeptider med endestillet carboxylsyreamidcarboxy - Google Patents

Fremgangsmaade til fremstilling af polypeptider med endestillet carboxylsyreamidcarboxy

Info

Publication number
DK365484D0
DK365484D0 DK365484A DK365484A DK365484D0 DK 365484 D0 DK365484 D0 DK 365484D0 DK 365484 A DK365484 A DK 365484A DK 365484 A DK365484 A DK 365484A DK 365484 D0 DK365484 D0 DK 365484D0
Authority
DK
Denmark
Prior art keywords
amino
peptides
genetic engineering
polypexylic
amode
Prior art date
Application number
DK365484A
Other languages
English (en)
Other versions
DK365484A (da
DK171940B1 (da
Inventor
Joachim Engels
Wolfgang Koenig
Hubert Muellner
Eugen Uhlmann
Waldemar Wetekam
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK365484D0 publication Critical patent/DK365484D0/da
Publication of DK365484A publication Critical patent/DK365484A/da
Application granted granted Critical
Publication of DK171940B1 publication Critical patent/DK171940B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK365484A 1983-07-27 1984-07-26 Fremgangsmåde til fremstilling af polypeptider meden C-terminal carboxamidgruppe, polypeptider til anvendelse ved fremgangsmåden, fusionsproteiner deraf og dertil egnede DNA-sekvenser, plasmider og værtsorganismer DK171940B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833327007 DE3327007A1 (de) 1983-07-27 1983-07-27 Herstellung von polypeptiden mit einem saeureamid-carboxyterminus
DE3327007 1983-07-27

Publications (3)

Publication Number Publication Date
DK365484D0 true DK365484D0 (da) 1984-07-26
DK365484A DK365484A (da) 1985-01-28
DK171940B1 DK171940B1 (da) 1997-08-18

Family

ID=6205008

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365484A DK171940B1 (da) 1983-07-27 1984-07-26 Fremgangsmåde til fremstilling af polypeptider meden C-terminal carboxamidgruppe, polypeptider til anvendelse ved fremgangsmåden, fusionsproteiner deraf og dertil egnede DNA-sekvenser, plasmider og værtsorganismer

Country Status (15)

Country Link
US (1) US5457033A (da)
EP (1) EP0133282B1 (da)
JP (1) JPH07121229B2 (da)
KR (1) KR850001287A (da)
AT (1) ATE68827T1 (da)
AU (1) AU572171B2 (da)
CA (1) CA1224166A (da)
DE (2) DE3327007A1 (da)
DK (1) DK171940B1 (da)
ES (1) ES8601303A1 (da)
GR (1) GR82436B (da)
IE (1) IE57664B1 (da)
IL (1) IL72489A0 (da)
PT (1) PT78979A (da)
ZA (1) ZA845779B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61291598A (ja) * 1985-06-18 1986-12-22 Sagami Chem Res Center 魚類カルシトニン誘導体及びその製造方法
JPS61257187A (ja) * 1985-05-11 1986-11-14 Sagami Chem Res Center サケカルシトニン誘導体遺伝子
DE3436819A1 (de) * 1984-10-06 1986-04-17 Hoechst Ag, 6230 Frankfurt Arzneimittel mit grf-wirkung
IT1234977B (it) * 1985-03-22 1992-06-09 Serono Ist Farm Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita
FR2587359B1 (fr) * 1985-05-28 1987-12-24 Sanofi Sa Derives non amides de la somatocrinine et procede de preparation par genie genetique
DK382886A (da) * 1985-08-12 1987-02-13 Syntex Inc Fremgangsmaade til fremstilling af hormonfaktorderivater
GB8523156D0 (en) * 1985-09-19 1985-10-23 Celltech Ltd Polypeptide production
US4865974A (en) * 1985-09-20 1989-09-12 Cetus Corporation Bacterial methionine N-terminal peptidase
DE3632037A1 (de) * 1986-09-20 1988-04-07 Hoechst Ag Gentechnisches verfahren zur herstellung von salm-calcitonin sowie mittel zur durchfuehrung dieses verfahrens
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
JPH01144981A (ja) * 1987-12-02 1989-06-07 Wakunaga Pharmaceut Co Ltd 蛋白質の製造
ATE119916T1 (de) * 1990-12-10 1995-04-15 Hoffmann La Roche Verfahren zur enzymatischen herstellung von grf(1-44)nh2.
GB0512610D0 (en) 2005-06-18 2005-07-27 Hexcel Composites Ltd Composite material

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0108387B1 (en) * 1982-11-04 1990-05-16 F. Hoffmann-La Roche Ag Preparation of recombinant growth releasing factors
US4581168A (en) * 1983-02-21 1986-04-08 Sanofi Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides
CA1254000A (en) * 1983-03-07 1989-05-09 Arthur M. Felix Growth hormone releasing factor analogs
ZA844380B (en) * 1983-07-05 1985-01-30 Salk Inst For Biological Studi Dna encoding a grf precursor
AU4727385A (en) * 1984-08-17 1986-03-07 Sagami Chemical Research Center Fish calcitonin derivative, process for its preparation, and gene system therefor

Also Published As

Publication number Publication date
IL72489A0 (en) 1984-11-30
AU3121784A (en) 1985-01-31
DK365484A (da) 1985-01-28
ZA845779B (en) 1985-02-27
JPS6049798A (ja) 1985-03-19
DK171940B1 (da) 1997-08-18
ATE68827T1 (de) 1991-11-15
EP0133282B1 (de) 1991-10-23
IE841930L (en) 1985-01-27
AU572171B2 (en) 1988-05-05
IE57664B1 (en) 1993-02-24
ES534589A0 (es) 1985-10-16
DE3485199D1 (da) 1991-11-28
EP0133282A1 (de) 1985-02-20
ES8601303A1 (es) 1985-10-16
JPH07121229B2 (ja) 1995-12-25
GR82436B (da) 1984-12-13
DE3327007A1 (de) 1985-02-07
US5457033A (en) 1995-10-10
CA1224166A (en) 1987-07-14
KR850001287A (ko) 1985-03-18
PT78979A (de) 1984-08-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired