DK368486A - Steroider der er virksomme mod cancer, obesitet, hyperglycaemi, autoimmunreaktion og hypercholesterolaemi - Google Patents

Steroider der er virksomme mod cancer, obesitet, hyperglycaemi, autoimmunreaktion og hypercholesterolaemi Download PDF

Info

Publication number
DK368486A
DK368486A DK368486A DK368486A DK368486A DK 368486 A DK368486 A DK 368486A DK 368486 A DK368486 A DK 368486A DK 368486 A DK368486 A DK 368486A DK 368486 A DK368486 A DK 368486A
Authority
DK
Denmark
Prior art keywords
obesidence
hypercholesterolaemia
hyperglycaemia
steroids
immune reaction
Prior art date
Application number
DK368486A
Other languages
English (en)
Other versions
DK368486D0 (da
DK171968B1 (da
Inventor
Arthur G Schwartz
Marvin Louis Lewbart
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of DK368486D0 publication Critical patent/DK368486D0/da
Publication of DK368486A publication Critical patent/DK368486A/da
Application granted granted Critical
Publication of DK171968B1 publication Critical patent/DK171968B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK368486A 1985-08-02 1986-08-01 5-androsten-17-on-forbindelser samt terapeutisk præparat, der indeholder en sådan forbindelse DK171968B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76258485A 1985-08-02 1985-08-02
US76258485 1985-08-02

Publications (3)

Publication Number Publication Date
DK368486D0 DK368486D0 (da) 1986-08-01
DK368486A true DK368486A (da) 1987-02-03
DK171968B1 DK171968B1 (da) 1997-09-01

Family

ID=25065487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK368486A DK171968B1 (da) 1985-08-02 1986-08-01 5-androsten-17-on-forbindelser samt terapeutisk præparat, der indeholder en sådan forbindelse

Country Status (11)

Country Link
EP (1) EP0210665B1 (da)
JP (1) JP2512439B2 (da)
AU (1) AU598201B2 (da)
CA (1) CA1314871C (da)
DE (1) DE3666437D1 (da)
DK (1) DK171968B1 (da)
ES (1) ES2000613A6 (da)
GR (1) GR862043B (da)
IE (1) IE58540B1 (da)
IL (1) IL79583A (da)
PT (1) PT83138B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84911B (pt) * 1986-05-21 1990-02-08 Research Corp Processo para a preparacao de esteroides uteis como agentes anti-cancerigenos e anti-obesidade
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
US5001119A (en) * 1987-11-25 1991-03-19 Schwartz Arthur G 16-substituted androstanes and 16-substituted androstenes
US5175154A (en) * 1987-11-25 1992-12-29 Research Corporation Technologies, Inc. 5 α-pregnan-20-ones and 5-pregnen-20-ones and related compounds
US5028631A (en) * 1987-11-25 1991-07-02 Schwartz Arthur G Homoandrostan-17-one and homoandrosten-17-ones
US5506223A (en) * 1990-08-29 1996-04-09 Humanetics Corporation Δ5-androstenes useful for promoting weight maintenance or weight loss and treatment process
US5585371A (en) * 1990-08-29 1996-12-17 Humanetics Corporation Treatment of immune system with Δ5-androstenes
JP3029907B2 (ja) * 1991-12-20 2000-04-10 理化学研究所 抗肥満剤
US5736537A (en) * 1995-09-12 1998-04-07 Estee Lauder, Inc. Dehydroep:androsterone sailcylate useful against skin atrophy
JP2001500841A (ja) * 1996-03-29 2001-01-23 エス ヴェー パテントフェアヴェアツングス ゲゼルシャフト ミット ベシュレンクテル ハフツンク 障害された皮下結合脂肪組織、とりわけ脂肪性浮腫の場合における皮膚を引きしめ滑らかにするための化粧品および化粧用組成物
CN103409144B (zh) * 2013-08-16 2014-11-26 东北大学 含甾体基元的环状碳酸酯类活泼液晶单体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS598074B2 (ja) * 1979-01-23 1984-02-22 沖電気工業株式会社 発光素子アレイ装置
JPS59155140U (ja) * 1983-04-06 1984-10-18 沖電気工業株式会社 光プリントヘツドの組立構造
ES8706717A1 (es) * 1983-08-02 1987-07-01 Research Corp Metodo de preparar esteroides
JPS6162016A (ja) * 1984-09-03 1986-03-29 Nhk Spring Co Ltd Ｌｅｄプリンタヘツド

Also Published As

Publication number Publication date
ES2000613A6 (es) 1988-03-01
JP2512439B2 (ja) 1996-07-03
AU598201B2 (en) 1990-06-21
CA1314871C (en) 1993-03-23
PT83138A (en) 1986-09-01
DK368486D0 (da) 1986-08-01
EP0210665A1 (en) 1987-02-04
IL79583A (en) 1990-11-29
IE58540B1 (en) 1993-10-06
EP0210665B1 (en) 1989-10-18
JPS6248693A (ja) 1987-03-03
PT83138B (pt) 1989-03-30
DK171968B1 (da) 1997-09-01
AU6079786A (en) 1987-02-05
IE862062L (en) 1987-02-02
GR862043B (en) 1986-12-24
DE3666437D1 (en) 1989-11-23
IL79583A0 (en) 1986-11-30

Similar Documents

Publication Publication Date Title
EP0247071A4 (en) IMMUNOTHERAPEUTIC TREATMENT.
DK40086A (da) Formaldehyd-bindemiddel, fremgangsmaade til fremstilling deraf og anvendelse deraf
DE3686463D1 (de) Empfaengnisverhuetendes mittel.
GB2172660B (en) Hydraulic noise attenuators
DK665187A (da) Immunoglobulin-konjugater og fremgangsmaade til fremstilling heraf
FI94003B (fi) Laajentuva nauha kaapeleita varten, sen käyttö ja kaapelit
DK368486A (da) Steroider der er virksomme mod cancer, obesitet, hyperglycaemi, autoimmunreaktion og hypercholesterolaemi
ZA876417B (en) Psa assembly
DK82686D0 (da) (1-benzyl-ethylendiamin)-platin(ii)-komplekser og fremgangsmaade til fremstilling heraf
FI870567A7 (fi) Tiivistys- ja liima-aine.
HUT41929A (en) Wide-band, space-split signal-switching apparatus
DE3161287D1 (en) Palladium (ii) catalyst, its preparation and application
NO884132L (no) Aluminiumoksyd-baserte katalysatorer og fremgangsmaate forderes fremstilling.
GB8528440D0 (en) Nitro anthracyclines
GB8610363D0 (en) Electroelution device
TR23713A (tr) Suebstituye edilmis tiouereler,izotiouereler ve korbadiimetiller
DK151788D0 (da) Hybridserpiner og dna, som koder derfor
DK396786A (da) Gem-dihalogen- og tetrahalogen-1,12-diamino-4,9-diazadedecaner, deresfremstilling og anvendelse
GB8619444D0 (en) Binding device
DK160087D0 (da) Katalysatorkomponent og fremgangsmaade til fremstilling deraf
GB2172163B (en) Attenuator apparatus
GB2175764B (en) Attenuator
NO870835D0 (no) Anordning for forming og pressing av ystel.
NO162724C (no) Fremgangsmaate til fremstilling av en polymerisasjonskatalysator og anvendelse av katalysatoren.
GB2189959B (en) Attenuator apparatus

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK