DK665187A - Immunoglobulin-konjugater og fremgangsmaade til fremstilling heraf - Google Patents
Immunoglobulin-konjugater og fremgangsmaade til fremstilling herafInfo
- Publication number
- DK665187A DK665187A DK665187A DK665187A DK665187A DK 665187 A DK665187 A DK 665187A DK 665187 A DK665187 A DK 665187A DK 665187 A DK665187 A DK 665187A DK 665187 A DK665187 A DK 665187A
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- preparing
- immunoglobulin conjugates
- conjugates
- immunoglobulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94635186A | 1986-12-24 | 1986-12-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK665187D0 DK665187D0 (da) | 1987-12-17 |
| DK665187A true DK665187A (da) | 1988-06-25 |
Family
ID=25484355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK665187A DK665187A (da) | 1986-12-24 | 1987-12-17 | Immunoglobulin-konjugater og fremgangsmaade til fremstilling heraf |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0272891A3 (da) |
| JP (1) | JPS63166897A (da) |
| KR (1) | KR880007531A (da) |
| CN (1) | CN1018649B (da) |
| AU (1) | AU590462B2 (da) |
| DK (1) | DK665187A (da) |
| HU (1) | HU205135B (da) |
| IE (1) | IE873450L (da) |
| IL (1) | IL84842A0 (da) |
| MX (1) | MX9847A (da) |
| NZ (1) | NZ222981A (da) |
| PT (1) | PT86377B (da) |
| RU (1) | RU1787160C (da) |
| ZA (1) | ZA879473B (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1312599C (en) * | 1988-02-16 | 1993-01-12 | Larry Wayne Hertel | 2',3'dideoxy-2',2'difluoronucleosides |
| MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
| US5273743A (en) * | 1990-03-09 | 1993-12-28 | Hybritech Incorporated | Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent |
| IL97459A0 (en) * | 1990-03-09 | 1992-06-21 | Hybritech Inc | Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent |
| WO1992014758A1 (en) * | 1991-02-13 | 1992-09-03 | The Austin Research Institute | Conjugate molecules |
| CN1076197C (zh) * | 1997-08-20 | 2001-12-19 | 许跃远 | 一种治疗乳腺疾病的药 |
| US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
| US7435755B2 (en) | 2000-11-28 | 2008-10-14 | The Trustees Of Dartmouth College | CDDO-compounds and combination therapies thereof |
| DK1465615T3 (da) | 2002-01-15 | 2012-11-12 | Dartmouth College | Tricykliske bisenonderivater og fremgangsmåder til anvendelse heraf |
| WO2004041203A2 (en) | 2002-11-04 | 2004-05-21 | Xenoport, Inc. | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof |
| US8921340B2 (en) | 2006-11-17 | 2014-12-30 | Trustees Of Dartmouth College | Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions |
| EP2094651A1 (en) | 2006-11-17 | 2009-09-02 | Trustees Of Dartmouth College | Synthesis and biological activities of new tricyclic-bis-enones (tbes) |
| WO2008064132A2 (en) | 2006-11-17 | 2008-05-29 | Trustees Of Dartmouth College | Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth |
| ME03529B (me) | 2008-01-11 | 2020-04-20 | Reata Pharmaceuticals Inc | Sintetički triterpenoidi i metode njihove upotrebe u tretmanu bolesti |
| EP2279197B1 (en) | 2008-04-18 | 2014-11-05 | Reata Pharmaceuticals, Inc. | Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the c-ring |
| HUE033288T2 (en) | 2008-04-18 | 2017-11-28 | Reata Pharmaceuticals Inc | Antioxidant inflammation modulators: C-17 homologated oleic acid derivatives |
| RS58392B1 (sr) | 2008-04-18 | 2019-04-30 | Reata Pharmaceuticals Inc | Antioksidantni modulatori inflamacije: derivati oleanoličke kiseline sa amino i drugim modifikacijama na c-17 |
| TW201006474A (en) | 2008-04-18 | 2010-02-16 | Reata Pharmaceuticals Inc | Natural products including an anti-flammatory pharmacore and methods of use |
| US8071632B2 (en) | 2008-04-18 | 2011-12-06 | Reata Pharmaceuticals, Inc. | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
| US8752322B2 (en) | 2012-01-13 | 2014-06-17 | Taurus International Manufacturing, Inc. | Body contoured handgun |
| EP2833905B1 (en) | 2012-04-04 | 2018-05-02 | Halozyme, Inc. | Combination therapy with hyaluronidase and a tumor-targeted taxane |
| US8921419B2 (en) | 2012-05-08 | 2014-12-30 | Trustees Of Dartmouth College | Triterpenoids and compositions containing the same |
| WO2019222435A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
| CN108610384B (zh) * | 2018-05-31 | 2022-02-22 | 沈阳药科大学 | 基于肠道mct1载体蛋白设计的前药及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4526988A (en) * | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| GR79899B (da) * | 1983-03-30 | 1984-10-31 | Lilly Industries Ltd | |
| DE3483336D1 (de) * | 1983-03-30 | 1990-11-08 | Lilly Industries Ltd | Vincaleukoblastin-derivate. |
| US4650675A (en) * | 1983-08-18 | 1987-03-17 | The Children's Medical Center Corporation | Oligonucleotide conjugates |
| DE3587500T2 (de) * | 1984-12-04 | 1993-12-16 | Lilly Co Eli | Tumorbehandlung bei Säugetieren. |
| US4675400A (en) * | 1985-06-17 | 1987-06-23 | Eli Lilly And Company | Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids |
| CA1295998C (en) * | 1985-07-29 | 1992-02-18 | Sai P. Sunkara | Nucleosides and their use as antineoplastic agents |
| US4762823A (en) * | 1985-10-16 | 1988-08-09 | Sloan-Kettering Institute For Cancer Research | Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil |
| US4751221A (en) * | 1985-10-18 | 1988-06-14 | Sloan-Kettering Institute For Cancer Research | 2-fluoro-arabinofuranosyl purine nucleosides |
-
1987
- 1987-12-16 IL IL84842A patent/IL84842A0/xx unknown
- 1987-12-16 RU SU874203967A patent/RU1787160C/ru active
- 1987-12-16 PT PT86377A patent/PT86377B/pt not_active IP Right Cessation
- 1987-12-17 KR KR870014370A patent/KR880007531A/ko not_active Withdrawn
- 1987-12-17 AU AU82659/87A patent/AU590462B2/en not_active Ceased
- 1987-12-17 ZA ZA879473A patent/ZA879473B/xx unknown
- 1987-12-17 DK DK665187A patent/DK665187A/da not_active Application Discontinuation
- 1987-12-18 JP JP62322619A patent/JPS63166897A/ja active Pending
- 1987-12-18 HU HU875862A patent/HU205135B/hu not_active IP Right Cessation
- 1987-12-18 NZ NZ222981A patent/NZ222981A/xx unknown
- 1987-12-18 CN CN87108348A patent/CN1018649B/zh not_active Expired
- 1987-12-18 IE IE873450A patent/IE873450L/xx unknown
- 1987-12-18 EP EP87311182A patent/EP0272891A3/en not_active Withdrawn
- 1987-12-18 MX MX984787A patent/MX9847A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR880007531A (ko) | 1988-08-27 |
| DK665187D0 (da) | 1987-12-17 |
| EP0272891A3 (en) | 1989-11-08 |
| JPS63166897A (ja) | 1988-07-11 |
| HUT45547A (en) | 1988-07-28 |
| RU1787160C (ru) | 1993-01-07 |
| EP0272891A2 (en) | 1988-06-29 |
| CN1018649B (zh) | 1992-10-14 |
| IE873450L (en) | 1988-06-24 |
| AU8265987A (en) | 1988-06-30 |
| HU205135B (en) | 1992-03-30 |
| IL84842A0 (en) | 1988-06-30 |
| ZA879473B (en) | 1989-08-30 |
| PT86377A (en) | 1988-01-01 |
| CN87108348A (zh) | 1988-07-13 |
| NZ222981A (en) | 1989-08-29 |
| AU590462B2 (en) | 1989-11-02 |
| MX9847A (es) | 1993-11-01 |
| PT86377B (pt) | 1990-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |