DK3709978T3 - Farmaceutisk oral formulering omfattende bakterier - Google Patents

Farmaceutisk oral formulering omfattende bakterier Download PDF

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Publication number
DK3709978T3
DK3709978T3 DK18803675.0T DK18803675T DK3709978T3 DK 3709978 T3 DK3709978 T3 DK 3709978T3 DK 18803675 T DK18803675 T DK 18803675T DK 3709978 T3 DK3709978 T3 DK 3709978T3
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DK
Denmark
Prior art keywords
bacteria
oral formulation
pharmaceutical oral
pharmaceutical
formulation
Prior art date
Application number
DK18803675.0T
Other languages
English (en)
Inventor
Carole Schwintner
Marianne Robin
Hervé Affagard
Cédric Michenet
Amandine Bardy
Jean-François Dubuisson
Original Assignee
Biocodex
Maat Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocodex, Maat Pharma filed Critical Biocodex
Application granted granted Critical
Publication of DK3709978T3 publication Critical patent/DK3709978T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK18803675.0T 2017-11-17 2018-11-16 Farmaceutisk oral formulering omfattende bakterier DK3709978T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17306602.8A EP3485879A1 (en) 2017-11-17 2017-11-17 Pharmaceutical oral formulation comrpsing bacteria
PCT/EP2018/081650 WO2019097030A1 (en) 2017-11-17 2018-11-16 Pharmaceutical oral formulation comprising bacteria

Publications (1)

Publication Number Publication Date
DK3709978T3 true DK3709978T3 (da) 2023-06-12

Family

ID=60473460

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18803675.0T DK3709978T3 (da) 2017-11-17 2018-11-16 Farmaceutisk oral formulering omfattende bakterier

Country Status (19)

Country Link
US (1) US11141440B2 (da)
EP (2) EP3485879A1 (da)
JP (1) JP7253546B2 (da)
KR (1) KR102742180B1 (da)
CN (1) CN111343972B (da)
AU (1) AU2018367230B2 (da)
CA (1) CA3079627C (da)
DK (1) DK3709978T3 (da)
ES (1) ES2947578T3 (da)
FI (1) FI3709978T3 (da)
HR (1) HRP20230647T1 (da)
HU (1) HUE062579T2 (da)
IL (1) IL273740B2 (da)
LT (1) LT3709978T (da)
PL (1) PL3709978T3 (da)
PT (1) PT3709978T (da)
RS (1) RS64290B1 (da)
SI (1) SI3709978T1 (da)
WO (1) WO2019097030A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4041264A1 (en) * 2019-10-07 2022-08-17 Siolta Therapeutics, Inc. Therapeutic pharmaceutical compositions
CN111413503A (zh) * 2020-03-28 2020-07-14 浙江大学 骨桥蛋白作为靶分子在调节高脂饮食引起的肥胖中的应用
EP3895716A1 (en) 2020-04-17 2021-10-20 Maat Pharma Fmt performance prediction test to guide and optimize therapeutic management of gvhd patients
CN111690044B (zh) * 2020-05-06 2022-03-01 中南大学湘雅二医院 Amuc1100蛋白的用途
AU2021405816A1 (en) 2020-12-23 2023-07-06 Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement Method of expanding a complex community of microorganisms
CN112826836A (zh) * 2021-01-08 2021-05-25 深圳未知君生物科技有限公司 一种粪菌口服制剂及其制备方法
JP2024525073A (ja) * 2021-07-09 2024-07-09 エボニック オペレーションズ ゲーエムベーハー 腸放出が改善された硬質シェルカプセル
KR20260053347A (ko) * 2023-08-15 2026-04-21 에보닉 오퍼레이션스 게엠베하 회장 및 결장에서의 투여 형태의 전달을 위한 장용성 코팅된 경질 쉘 캡슐
WO2025141323A1 (en) * 2023-12-29 2025-07-03 Maat Pharma Compositions used in combination with immune modulatory treatments for treating cancers
CN117603884B (zh) * 2024-01-17 2024-03-26 广州同康生物科技有限公司 一种嗜黏蛋白阿克曼氏菌菌粉及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG80553A1 (en) * 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
PL2187875T3 (pl) * 2007-09-21 2013-01-31 Evonik Roehm Gmbh Kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu dla nieopioidów z odpornością przed wpływem etanolu
JP2016501852A (ja) * 2012-11-26 2016-01-21 トーマス・ジュリアス・ボロディ 糞便微生物叢の回復のための組成物、ならびにそれらを作製および使用する方法
AU2014239883B2 (en) * 2013-03-14 2019-01-17 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
CA2950203C (en) * 2014-06-20 2019-09-03 Banner Life Sciences Llc Enteric soft capsule compositions
AU2015334468B2 (en) 2014-10-23 2021-06-17 Institut Gustave Roussy Methods and products for modulating microbiota composition for improving the efficacy of a cancer treatment with an immune checkpoint blocker
CN104490848B (zh) * 2014-12-31 2018-01-30 四川峨嵋山药业有限公司 一种雷替曲塞结肠定位微丸及其制备方法
FR3035328B1 (fr) 2015-04-24 2019-08-23 Maat Pharma Procede de preparation d'un echantillon de microbiote fecal
CN107921072A (zh) 2015-06-09 2018-04-17 雷柏奥提斯有限公司 微生物群恢复治疗(mrt)组合物和制造方法
FR3045383B1 (fr) 2015-12-18 2019-06-14 Maat Pharma Procede de lyophilisation d'un echantillon de microbiote fecal

Also Published As

Publication number Publication date
SI3709978T1 (sl) 2023-09-29
HRP20230647T1 (hr) 2023-09-29
CA3079627C (en) 2023-06-13
IL273740B2 (en) 2024-04-01
CN111343972B (zh) 2022-10-28
LT3709978T (lt) 2023-08-10
CN111343972A (zh) 2020-06-26
US11141440B2 (en) 2021-10-12
RS64290B1 (sr) 2023-07-31
US20200345790A1 (en) 2020-11-05
KR102742180B1 (ko) 2024-12-11
AU2018367230A1 (en) 2020-05-07
JP2021503452A (ja) 2021-02-12
ES2947578T3 (es) 2023-08-11
PL3709978T3 (pl) 2023-10-02
WO2019097030A1 (en) 2019-05-23
IL273740A (en) 2020-05-31
EP3709978B1 (en) 2023-04-05
IL273740B1 (en) 2023-12-01
KR20200088395A (ko) 2020-07-22
AU2018367230B2 (en) 2023-06-08
CA3079627A1 (en) 2019-05-23
PT3709978T (pt) 2023-07-11
HUE062579T2 (hu) 2023-11-28
JP7253546B2 (ja) 2023-04-06
EP3709978A1 (en) 2020-09-23
EP3485879A1 (en) 2019-05-22
FI3709978T3 (fi) 2023-06-28
EP3709978B8 (en) 2023-05-31

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