DK3761982T3 - Anvendelse af nalfurafin til behandling af demyeliniserende sygdomme - Google Patents
Anvendelse af nalfurafin til behandling af demyeliniserende sygdomme Download PDFInfo
- Publication number
- DK3761982T3 DK3761982T3 DK19765122.7T DK19765122T DK3761982T3 DK 3761982 T3 DK3761982 T3 DK 3761982T3 DK 19765122 T DK19765122 T DK 19765122T DK 3761982 T3 DK3761982 T3 DK 3761982T3
- Authority
- DK
- Denmark
- Prior art keywords
- nalfurafine
- treatment
- demyelinating diseases
- demyelinating
- diseases
- Prior art date
Links
- 208000016192 Demyelinating disease Diseases 0.000 title 1
- XGZZHZMWIXFATA-UEZBDDGYSA-N nalfurafine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]1(O)CC[C@H]3N(C)C(=O)\C=C\C1=COC=C1)CN2CC1CC1 XGZZHZMWIXFATA-UEZBDDGYSA-N 0.000 title 1
- 229960000441 nalfurafine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018900754A AU2018900754A0 (en) | 2018-03-08 | Treatment of demyelinating diseases | |
| PCT/IB2019/051870 WO2019171333A1 (en) | 2018-03-08 | 2019-03-07 | Treatment of demyelinating diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3761982T3 true DK3761982T3 (da) | 2025-01-02 |
Family
ID=67846938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19765122.7T DK3761982T3 (da) | 2018-03-08 | 2019-03-07 | Anvendelse af nalfurafin til behandling af demyeliniserende sygdomme |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20210015813A1 (da) |
| EP (1) | EP3761982B1 (da) |
| AU (1) | AU2019229892B2 (da) |
| CA (1) | CA3091752A1 (da) |
| DK (1) | DK3761982T3 (da) |
| ES (1) | ES3006014T3 (da) |
| FI (1) | FI3761982T3 (da) |
| HU (1) | HUE069820T2 (da) |
| PL (1) | PL3761982T3 (da) |
| PT (1) | PT3761982T (da) |
| WO (1) | WO2019171333A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3091752A1 (en) | 2018-03-08 | 2019-09-12 | Victoria Link Ltd | Treatment of demyelinating diseases |
| CN115697371A (zh) | 2020-03-20 | 2023-02-03 | 维也纳医科大学 | 大环寡肽与κ阿片样物质受体配体组合用于MS疗法 |
| AU2024265731A1 (en) * | 2023-05-02 | 2025-12-11 | Cognito Therapeutics, Inc. | Gamma stimulation and neuromodulator combination therapy |
| WO2025255116A1 (en) * | 2024-06-03 | 2025-12-11 | The Cleveland Clinic Foundation | Methods of treatment for opioid-induced ventilatory depression and muscle rigidity |
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| US4994466A (en) | 1990-06-14 | 1991-02-19 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for multiple sclerosis |
| JP2525552B2 (ja) | 1992-01-23 | 1996-08-21 | 東レ株式会社 | モルヒナン誘導体および医薬用途 |
| AU712012B2 (en) | 1995-09-26 | 1999-10-28 | Toray Industries, Inc. | Indole derivatives and medical application thereof |
| US6440987B1 (en) | 1996-11-25 | 2002-08-27 | Toray Industries, Inc. | Antipruritic |
| CN1535687A (zh) | 1996-11-25 | 2004-10-13 | ������������ʽ���� | 止痒药物 |
| CA2265767C (en) | 1997-07-11 | 2007-12-04 | Nobuyuki Hanamura | Stable pharmaceutical composition including 4,5-epoxy-morphinan derivative |
| JP2000053572A (ja) | 1998-08-11 | 2000-02-22 | Toray Ind Inc | ＯＲＬ１（ｏｐｉｏｉｄ ｏｒｐｈａｎ）受容体拮抗薬 |
| ES2308990T3 (es) | 1999-08-24 | 2008-12-16 | Toray Industries, Inc. | Remedios para el dolor neuropatico y modelos animales de dolor neuropatico. |
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| AU2408602A (en) | 2000-11-22 | 2002-06-03 | Toray Industries | Indole derivatives and use thereof in medicines |
| JP4453254B2 (ja) | 2001-03-30 | 2010-04-21 | 東レ株式会社 | レストレス・レッグズ症候群治療薬 |
| JP2002332284A (ja) | 2001-05-08 | 2002-11-22 | Toray Ind Inc | 二価性モルヒナン誘導体およびその医薬用途 |
| JP4957489B2 (ja) | 2002-10-09 | 2012-06-20 | 東レ株式会社 | 含窒素環状置換基を有するモルヒナン誘導体またはその薬理学的に許容される酸付加塩を含有する医薬 |
| CN100537573C (zh) | 2002-10-09 | 2009-09-09 | 东丽株式会社 | 尿频或尿失禁的治疗或预防剂以及具有含氮环状取代基的吗啡烷衍生物 |
| DE602005011113D1 (de) | 2004-03-30 | 2009-01-02 | Toray Industries | Morphinanderivate als mittel gegen juckreiz |
| US20060069086A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| TW200621785A (en) | 2004-11-04 | 2006-07-01 | Toray Industries | Analgesic |
| CN101137658B (zh) | 2005-03-10 | 2011-06-08 | 东丽株式会社 | 用于与多发性硬化症伴随的搔痒的止痒剂 |
| RU2397173C2 (ru) | 2005-04-06 | 2010-08-20 | Торей Индастриз, Инк. | Кристаллические производные морфинана и способ их получения |
| TW200806294A (en) | 2005-11-09 | 2008-02-01 | Toray Industries | Therapeutic or prophylactic agent for functional intestinal injury |
| CA2634055C (en) | 2005-12-21 | 2011-07-05 | Toray Industries, Inc. | Antitussive agent |
| WO2008024490A2 (en) | 2006-08-24 | 2008-02-28 | Theraquest Biosciences, Inc. | Oral pharmaceutical formulations of abuse deterrent cannabinoids and method of use |
| MX2009011449A (es) | 2007-04-24 | 2010-01-25 | Toray Industries | Agente terapeutico o profilactico para disquinesia. |
| CA2685131C (en) | 2007-04-26 | 2015-05-19 | Toray Industries, Inc. | Stable solid preparation containing 4,5-epoxymorphinan derivative |
| BRPI0817804A8 (pt) | 2007-10-05 | 2017-04-18 | Toray Industries | Agente terapêutico para melhorar as propriedades da pele compreendendo um derivado de morfinano ou qualquer um de seus sais de adição de ácido farmacologicamente permissíveis como um ingrediente ativo |
| JP5252391B2 (ja) | 2008-02-21 | 2013-07-31 | 学校法人北里研究所 | オキサビシクロ［２．２．２］オクタンを有するモルヒナン誘導体およびその医薬用途 |
| DK2356989T3 (da) * | 2008-10-24 | 2018-05-07 | Toray Industries | Stabil tablet indeholdende 4,5-epoxymorphinanderivat |
| TWI455733B (zh) | 2009-03-30 | 2014-10-11 | Toray Industries | 口腔內崩壞性被覆錠劑 |
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| CA2892687C (en) | 2012-12-19 | 2021-08-03 | The Regents Of The University Of California | Micropillar arrays for assaying myelination |
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| JP2016155794A (ja) | 2014-06-09 | 2016-09-01 | 富士カプセル株式会社 | ナルフラフィン塩酸塩及びフィチン酸又はその塩を含有するカプセル製剤 |
| CN105462930B (zh) | 2014-06-24 | 2020-10-20 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种筛选κ阿片受体激动剂的细胞模型及筛选方法 |
| TW201707703A (zh) * | 2015-06-04 | 2017-03-01 | Tokai Capsule Co Ltd | 軟膠囊劑 |
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| EP3603643B1 (en) | 2017-03-31 | 2021-09-15 | Toray Industries, Inc. | Tableted medicinal composition comprising nalfurafine |
| EP3761981A4 (en) | 2018-03-08 | 2021-12-15 | Victoria Link Ltd | TREATMENT OF DEMYELINIZING DISEASES |
| CA3091752A1 (en) | 2018-03-08 | 2019-09-12 | Victoria Link Ltd | Treatment of demyelinating diseases |
-
2019
- 2019-03-07 CA CA3091752A patent/CA3091752A1/en active Pending
- 2019-03-07 FI FIEP19765122.7T patent/FI3761982T3/fi active
- 2019-03-07 US US16/978,542 patent/US20210015813A1/en not_active Abandoned
- 2019-03-07 ES ES19765122T patent/ES3006014T3/es active Active
- 2019-03-07 EP EP19765122.7A patent/EP3761982B1/en active Active
- 2019-03-07 PT PT197651227T patent/PT3761982T/pt unknown
- 2019-03-07 HU HUE19765122A patent/HUE069820T2/hu unknown
- 2019-03-07 WO PCT/IB2019/051870 patent/WO2019171333A1/en not_active Ceased
- 2019-03-07 PL PL19765122.7T patent/PL3761982T3/pl unknown
- 2019-03-07 AU AU2019229892A patent/AU2019229892B2/en active Active
- 2019-03-07 DK DK19765122.7T patent/DK3761982T3/da active
-
2020
- 2020-07-23 US US16/936,975 patent/US11324742B2/en active Active
-
2022
- 2022-09-30 US US17/957,350 patent/US12318380B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019171333A1 (en) | 2019-09-12 |
| US11324742B2 (en) | 2022-05-10 |
| PL3761982T3 (pl) | 2025-03-17 |
| US12318380B2 (en) | 2025-06-03 |
| US20210015813A1 (en) | 2021-01-21 |
| EP3761982A1 (en) | 2021-01-13 |
| US20210069179A1 (en) | 2021-03-11 |
| FI3761982T3 (fi) | 2025-01-03 |
| US20230096920A1 (en) | 2023-03-30 |
| RU2020128028A (ru) | 2022-04-08 |
| AU2019229892B2 (en) | 2025-01-30 |
| AU2019229892A1 (en) | 2020-09-03 |
| HUE069820T2 (hu) | 2025-04-28 |
| EP3761982A4 (en) | 2021-12-15 |
| EP3761982B1 (en) | 2024-10-09 |
| PT3761982T (pt) | 2024-12-30 |
| CA3091752A1 (en) | 2019-09-12 |
| ES3006014T3 (en) | 2025-03-17 |
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