DK3658132T3 - Sammensætninger omfattende aminosyrer til anvendelse ved behandling af mitokondrielle dysfunktion-relaterede sygdomme - Google Patents
Sammensætninger omfattende aminosyrer til anvendelse ved behandling af mitokondrielle dysfunktion-relaterede sygdomme Download PDFInfo
- Publication number
- DK3658132T3 DK3658132T3 DK18753465.6T DK18753465T DK3658132T3 DK 3658132 T3 DK3658132 T3 DK 3658132T3 DK 18753465 T DK18753465 T DK 18753465T DK 3658132 T3 DK3658132 T3 DK 3658132T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- treatment
- amino acids
- related diseases
- mitochondrial dysfunction
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000004065 mitochondrial dysfunction Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102017000087359A IT201700087359A1 (it) | 2017-07-28 | 2017-07-28 | Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale |
| PCT/IB2018/055425 WO2019021135A1 (en) | 2017-07-28 | 2018-07-20 | COMPOSITIONS COMPRISING AMINO ACIDS FOR USE IN THE TREATMENT OF DISEASES RELATED TO MITOCHONDRIAL DYSFUNCTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3658132T3 true DK3658132T3 (da) | 2022-07-04 |
Family
ID=60628070
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK21174744.9T DK3915553T3 (da) | 2017-07-28 | 2018-07-20 | Sammensætninger indeholdende aminosyrer til brug i behandlingen af mitokondrie-dysfunktion-relaterede neurodegenerative sygdomme |
| DK18753465.6T DK3658132T3 (da) | 2017-07-28 | 2018-07-20 | Sammensætninger omfattende aminosyrer til anvendelse ved behandling af mitokondrielle dysfunktion-relaterede sygdomme |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK21174744.9T DK3915553T3 (da) | 2017-07-28 | 2018-07-20 | Sammensætninger indeholdende aminosyrer til brug i behandlingen af mitokondrie-dysfunktion-relaterede neurodegenerative sygdomme |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US11337946B2 (da) |
| EP (2) | EP3915553B1 (da) |
| JP (2) | JP7266767B2 (da) |
| KR (3) | KR102566297B1 (da) |
| CN (1) | CN110996935A (da) |
| AU (2) | AU2018306540B2 (da) |
| BR (1) | BR112020001471A2 (da) |
| CA (1) | CA3070197C (da) |
| CL (1) | CL2020000220A1 (da) |
| DK (2) | DK3915553T3 (da) |
| ES (2) | ES3031608T3 (da) |
| HU (1) | HUE059050T2 (da) |
| IT (1) | IT201700087359A1 (da) |
| LT (1) | LT3658132T (da) |
| MX (2) | MX395240B (da) |
| MY (1) | MY200975A (da) |
| PH (1) | PH12020500190A1 (da) |
| PL (2) | PL3915553T3 (da) |
| PT (2) | PT3658132T (da) |
| RS (1) | RS63422B1 (da) |
| SG (1) | SG11201912103TA (da) |
| WO (1) | WO2019021135A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201700087359A1 (it) | 2017-07-28 | 2019-01-28 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale |
| IT201700087376A1 (it) | 2017-07-28 | 2019-01-28 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale |
| IT201800006725A1 (it) | 2018-06-27 | 2019-12-27 | Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche | |
| IT201900002109A1 (it) | 2019-02-13 | 2020-08-13 | Professional Dietetics Spa | Composizioni comprendenti amminoacidi per l'uso nel trattamento di lesioni del sistema nervoso centrale |
| JP2021038147A (ja) * | 2019-08-30 | 2021-03-11 | 国立大学法人 鹿児島大学 | ミトコンドリア生合成促進剤 |
| IT202000000454A1 (it) * | 2020-01-13 | 2021-07-13 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per la prevenzione e il trattamento del cancro |
| IT202000000442A1 (it) * | 2020-01-13 | 2021-07-13 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia |
| WO2021198400A1 (en) * | 2020-04-01 | 2021-10-07 | Société des Produits Nestlé S.A. | Compositions containing amino acids and methods of using such compositions for treating sarcopenia |
| IT202000021664A1 (it) * | 2020-09-14 | 2022-03-14 | Iaf Network S P A | Formulazione amminoacidica bilanciata |
| TW202308604A (zh) * | 2021-05-10 | 2023-03-01 | 國立大學法人東北大學 | 肌肉量增加用組成物 |
| IT202100029726A1 (it) | 2021-11-24 | 2023-05-24 | Professional Dietetics Spa | Composizioni oftalmiche per il trattamento di lesioni corneali |
| KR20250035239A (ko) | 2023-09-05 | 2025-03-12 | 메디컬아이피 주식회사 | 의료영상 내 관형구조물의 직경파악방법 및 그 장치 |
| CN120661636A (zh) * | 2025-06-12 | 2025-09-19 | 中国医学科学院医学实验动物研究所 | 一种胞质特异性表达ppm1k的基因递送系统及其制备方法和应用 |
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| AU760140B2 (en) | 1997-10-24 | 2003-05-08 | John P. Blass | Nutritional supplement for cerebral metabolic insufficiencies |
| DE10000577A1 (de) | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
| ITTO20010580A1 (it) | 2001-06-15 | 2002-12-15 | Professional Dietetics Srl | Composizioni a base di aminoacidi per il miglioramento della funzioneventricolare miocardica in pazienti affetti da diabete. |
| ITTO20010804A1 (it) | 2001-08-08 | 2003-02-08 | Professional Dietetics Srl | Composizioni a base di aminoacidi, idonee alla terapia per la cicatrizzazione e/o riparazione di ferite e lesioni, in particolare per l'appl |
| US6620850B2 (en) | 2001-09-19 | 2003-09-16 | University Of Florida | Materials and methods for treatment of neurological disorders involving overactivation of glutamatergic ionotropic receptors |
| US20060063827A1 (en) * | 2004-09-23 | 2006-03-23 | Yu Ruey J | Systemic administration of therapeutic amino acids and N-acetylamino acids |
| ITTO20030789A1 (it) | 2003-10-07 | 2005-04-08 | Professional Dietetics Srl | Composizione a base di amino acidi per il trattamento |
| WO2007049818A1 (ja) | 2005-10-27 | 2007-05-03 | Ajinomoto Co., Inc. | 抗脂肪肝、抗肥満及び抗高脂血症用組成物 |
| US7982066B2 (en) * | 2005-12-09 | 2011-07-19 | Novalife, Inc. | High protein supplement |
| JP2007161642A (ja) | 2005-12-14 | 2007-06-28 | Kyowa Hakko Kogyo Co Ltd | アルコール性肝障害抑制剤 |
| JP6090836B2 (ja) | 2011-02-17 | 2017-03-08 | Ｅａファーマ株式会社 | 化学療法剤の抗腫瘍活性増強剤 |
| WO2012147901A1 (ja) | 2011-04-28 | 2012-11-01 | 味の素株式会社 | 抗癌剤副作用改善用組成物 |
| US20130084378A1 (en) | 2011-09-30 | 2013-04-04 | Daesang Corporation | Amino acid seasoning compositions comprising l-glutamic acid and l-lysine |
| US9198454B2 (en) | 2012-03-08 | 2015-12-01 | Nusirt Sciences, Inc. | Compositions, methods, and kits for regulating energy metabolism |
| US20160038565A1 (en) | 2012-06-15 | 2016-02-11 | Gencia Corporation | Methods of Mitigating Side Effects of Radiation Exposure and Chemotherapy |
| CN102772407B (zh) | 2012-08-01 | 2014-09-17 | 岳茂兴 | 一种促进神经损伤修复的药物组合物及其应用 |
| US9597367B2 (en) * | 2013-04-19 | 2017-03-21 | Bioventures, Llc | Methods for improving muscle and heart function |
| US10226441B2 (en) | 2014-12-09 | 2019-03-12 | Nihon Sizen Hakkoh Co., Ltd. | Aging inhibitor |
| MX357998B (es) * | 2015-03-20 | 2018-07-11 | Antonio Hernandez Miramontes Jorge | Una mezcla de acidos carboxilicos, especificamente acido citrico, acido succinico, acido fumarico y acido malico para el tratamiento de pacientes con insuficiencia renal cronica, insuficiencia renal aguda, hepatopatias agudas o cronicas que cursen con hiperamonemia, enfermedades congenitas con alteraciones enzimaticas en el ciclo de la urea, asi como condiciones clínicas que cursen con balance nitrogenado negativo. |
| CN107708683A (zh) * | 2015-05-11 | 2018-02-16 | 纽卡斯尔创新有限公司 | 氨基酸补充 |
| CA2981757C (en) | 2015-05-14 | 2023-06-27 | Professional Dietetics S.P.A. | Compositions comprising amino acids for use in the treatment of mucositides in neoplasia patients undergoing radiation therapy and/or chemotherapy |
| WO2017020121A1 (en) | 2015-07-31 | 2017-02-09 | Val-Chum, Limited Partnership | Glycerol-3-phosphate phosphatase activators |
| RU2741637C2 (ru) | 2015-11-27 | 2021-01-28 | Даблгуд Аб | Пищевая добавка и композиция для лечения метаболического синдрома |
| US11617731B2 (en) | 2017-04-28 | 2023-04-04 | Axcella Health, Inc. | Amino acid compositions and their use for the treatment of traumatic brain injury |
| IT201700087376A1 (it) | 2017-07-28 | 2019-01-28 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale |
| IT201700087359A1 (it) | 2017-07-28 | 2019-01-28 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale |
| US12109191B2 (en) | 2017-10-02 | 2024-10-08 | Amilyfe, Llc | Materials and methods for inhibiting tumor growth |
| CN111867575B (zh) * | 2018-03-05 | 2023-09-29 | 味之素株式会社 | 用于改善认知功能的组合物、用于改善焦虑样症状的组合物和用于抑制脑萎缩的组合物 |
| IT201800006725A1 (it) | 2018-06-27 | 2019-12-27 | Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche | |
| IT201900002109A1 (it) | 2019-02-13 | 2020-08-13 | Professional Dietetics Spa | Composizioni comprendenti amminoacidi per l'uso nel trattamento di lesioni del sistema nervoso centrale |
| KR102864330B1 (ko) | 2019-11-11 | 2025-09-25 | 엘지전자 주식회사 | 무선통신시스템에서 동작하는 차량용 분산 안테나 시스템 및 그 동작 방법 |
| IT202000000442A1 (it) | 2020-01-13 | 2021-07-13 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia |
| IT202000000454A1 (it) | 2020-01-13 | 2021-07-13 | Professional Dietetics Spa | Composizioni comprendenti amino acidi per la prevenzione e il trattamento del cancro |
| WO2022266480A1 (en) | 2021-06-17 | 2022-12-22 | Axcella Health Inc. | Methods of predicting liver fat content and uses thereof |
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2017
- 2017-07-28 IT IT102017000087359A patent/IT201700087359A1/it unknown
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2018
- 2018-07-20 KR KR1020207003492A patent/KR102566297B1/ko active Active
- 2018-07-20 WO PCT/IB2018/055425 patent/WO2019021135A1/en not_active Ceased
- 2018-07-20 EP EP21174744.9A patent/EP3915553B1/en active Active
- 2018-07-20 KR KR1020247014645A patent/KR20240063205A/ko not_active Ceased
- 2018-07-20 PL PL21174744.9T patent/PL3915553T3/pl unknown
- 2018-07-20 RS RS20220627A patent/RS63422B1/sr unknown
- 2018-07-20 DK DK21174744.9T patent/DK3915553T3/da active
- 2018-07-20 ES ES21174744T patent/ES3031608T3/es active Active
- 2018-07-20 DK DK18753465.6T patent/DK3658132T3/da active
- 2018-07-20 AU AU2018306540A patent/AU2018306540B2/en active Active
- 2018-07-20 SG SG11201912103TA patent/SG11201912103TA/en unknown
- 2018-07-20 KR KR1020237026054A patent/KR20230117642A/ko not_active Ceased
- 2018-07-20 HU HUE18753465A patent/HUE059050T2/hu unknown
- 2018-07-20 PL PL18753465.6T patent/PL3658132T3/pl unknown
- 2018-07-20 CN CN201880047542.0A patent/CN110996935A/zh active Pending
- 2018-07-20 CA CA3070197A patent/CA3070197C/en active Active
- 2018-07-20 ES ES18753465T patent/ES2923126T3/es active Active
- 2018-07-20 JP JP2019566579A patent/JP7266767B2/ja active Active
- 2018-07-20 US US16/634,330 patent/US11337946B2/en active Active
- 2018-07-20 MX MX2020001083A patent/MX395240B/es unknown
- 2018-07-20 PT PT187534656T patent/PT3658132T/pt unknown
- 2018-07-20 BR BR112020001471-0A patent/BR112020001471A2/pt unknown
- 2018-07-20 PT PT211747449T patent/PT3915553T/pt unknown
- 2018-07-20 EP EP18753465.6A patent/EP3658132B1/en active Active
- 2018-07-20 MY MYPI2020000106A patent/MY200975A/en unknown
- 2018-07-20 LT LTEPPCT/IB2018/055425T patent/LT3658132T/lt unknown
-
2020
- 2020-01-27 MX MX2022010774A patent/MX2022010774A/es unknown
- 2020-01-27 CL CL2020000220A patent/CL2020000220A1/es unknown
- 2020-01-27 PH PH12020500190A patent/PH12020500190A1/en unknown
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2022
- 2022-04-20 US US17/724,537 patent/US11957651B2/en active Active
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2023
- 2023-03-08 JP JP2023035509A patent/JP7513311B2/ja active Active
- 2023-11-14 AU AU2023266256A patent/AU2023266256B2/en active Active
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