DK377984D0 - Azulenderivater, fremgangsmaader til deres syntese og deres anvendelsersom anti-ulcerative og anti-inflammatoriske midler - Google Patents

Azulenderivater, fremgangsmaader til deres syntese og deres anvendelsersom anti-ulcerative og anti-inflammatoriske midler

Info

Publication number
DK377984D0
DK377984D0 DK377984A DK377984A DK377984D0 DK 377984 D0 DK377984 D0 DK 377984D0 DK 377984 A DK377984 A DK 377984A DK 377984 A DK377984 A DK 377984A DK 377984 D0 DK377984 D0 DK 377984D0
Authority
DK
Denmark
Prior art keywords
azulender
ulcerative
procedures
synthesis
derivatives
Prior art date
Application number
DK377984A
Other languages
English (en)
Other versions
DK169870B1 (da
DK377984A (da
Inventor
Kahei Takase
Masafumi Yasunami
Tsuyoshi Tomiyama
Akira Tomiyama
Takashi Yanagisawa
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP15318783A external-priority patent/JPS6048960A/ja
Priority claimed from JP1402884A external-priority patent/JPS60158160A/ja
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Publication of DK377984D0 publication Critical patent/DK377984D0/da
Publication of DK377984A publication Critical patent/DK377984A/da
Application granted granted Critical
Publication of DK169870B1 publication Critical patent/DK169870B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/47—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having at least one of the sulfo groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK377984A 1983-08-24 1984-08-03 Azulenderivater, fremgangsmåde til deres syntese og anti-ulcerative og anti-inflammatoriske midler omfattende disse derivater DK169870B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP15318783 1983-08-24
JP15318783A JPS6048960A (ja) 1983-08-24 1983-08-24 アズレン誘導体及びその製法並びにこの化合物を有効成分とする抗潰瘍剤
JP1402884A JPS60158160A (ja) 1984-01-28 1984-01-28 アズレン誘導体スルホン酸塩、抗潰瘍、抗炎症剤及びその製法
JP1402884 1984-01-28

Publications (3)

Publication Number Publication Date
DK377984D0 true DK377984D0 (da) 1984-08-03
DK377984A DK377984A (da) 1985-02-25
DK169870B1 DK169870B1 (da) 1995-03-20

Family

ID=26349908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK377984A DK169870B1 (da) 1983-08-24 1984-08-03 Azulenderivater, fremgangsmåde til deres syntese og anti-ulcerative og anti-inflammatoriske midler omfattende disse derivater

Country Status (13)

Country Link
US (1) US4595694A (da)
EP (1) EP0147915B1 (da)
KR (1) KR920000956B1 (da)
AR (1) AR240554A1 (da)
AU (1) AU571554B2 (da)
CA (1) CA1228862A (da)
DE (1) DE3463502D1 (da)
DK (1) DK169870B1 (da)
ES (1) ES8506607A1 (da)
HU (1) HU195478B (da)
NO (1) NO158673C (da)
PT (1) PT79119B (da)
SU (1) SU1311618A3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081152A (en) * 1989-07-05 1992-01-14 Kotobuki Seiyaku Co., Ltd. Azulene derivatives as thromboxane a2 and prostaglandin endoperoxide receptor antagonist
EP0887077A1 (de) * 1997-06-27 1998-12-30 Boehringer Mannheim Gmbh Verwendung von Azulenderivaten als Metalloproteaseinhibitoren
US6420435B1 (en) 1999-11-01 2002-07-16 Joe S. Wilkins, Jr. Method for treating gastrointestinal disorders
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US7041706B2 (en) * 2002-04-19 2006-05-09 Wilkins Jr Joe S Method for treating crohn's disease
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1227896B (de) * 1965-12-02 1966-11-03 Degussa Verfahren zur Herstellung wasserloeslicher stabiler Salze von Azulensulfonsaeureamiden
US3816612A (en) * 1967-03-23 1974-06-11 Degussa Process for the production of basically reacting pharmaceuticals
US3974299A (en) * 1974-07-08 1976-08-10 Dynapol Ionic sweetener
US4224240A (en) * 1979-04-13 1980-09-23 Scm Corporation Preparation of para-menth-1-ene-7-sulfonate salts and corresponding acids
US4283347A (en) * 1979-04-13 1981-08-11 Scm Corporation Para-menth-1-ene-7-sulfonic acid and salts thereof

Also Published As

Publication number Publication date
ES535381A0 (es) 1985-07-16
ES8506607A1 (es) 1985-07-16
NO158673C (no) 1988-10-19
AR240554A1 (es) 1990-05-31
NO843377L (no) 1985-02-25
DE3463502D1 (en) 1987-06-11
DK169870B1 (da) 1995-03-20
PT79119B (en) 1986-07-17
KR850001731A (ko) 1985-04-01
SU1311618A3 (ru) 1987-05-15
NO158673B (no) 1988-07-11
AU571554B2 (en) 1988-04-21
DK377984A (da) 1985-02-25
EP0147915B1 (en) 1987-05-06
AU3139684A (en) 1985-02-28
EP0147915A1 (en) 1985-07-10
HUT37393A (en) 1985-12-28
HU195478B (en) 1988-05-30
KR920000956B1 (ko) 1992-01-31
CA1228862A (en) 1987-11-03
US4595694A (en) 1986-06-17
PT79119A (en) 1984-09-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

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