DK377985A - Fremgangsmaade til fremstilling af vaeksthormoner - Google Patents

Fremgangsmaade til fremstilling af vaeksthormoner Download PDF

Info

Publication number: DK377985A
Authority: DK; Denmark
Prior art keywords: hormone; analog; ultrafiltration; separating; purified
Prior art date: 1984-08-27

Application number

DK377985A

Other languages

English (en)

Other versions

DK174889B1 (da

DK377985D0 (da

Inventor

Daniel Bartfeld

Shmaryahu Blumberg

Marian Gorecki

Dan Hadary

Menachem Zeevi

Original Assignee

Bio Technology General Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-27

Filing date

1985-08-20

Publication date

1986-02-28

1985-08-20 Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp

1985-08-20 Publication of DK377985D0 publication Critical patent/DK377985D0/da

1986-02-28 Publication of DK377985A publication Critical patent/DK377985A/da

2004-01-19 Application granted granted Critical

2004-01-19 Publication of DK174889B1 publication Critical patent/DK174889B1/da

Links

239000000122 growth hormone Substances 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 4
239000005556 hormone Substances 0.000 abstract 7
229940088597 hormone Drugs 0.000 abstract 7
230000001580 bacterial effect Effects 0.000 abstract 3
210000004027 cell Anatomy 0.000 abstract 3
239000002244 precipitate Substances 0.000 abstract 3
239000000725 suspension Substances 0.000 abstract 3
238000000108 ultra-filtration Methods 0.000 abstract 3
102000018997 Growth Hormone Human genes 0.000 abstract 2
108010051696 Growth Hormone Proteins 0.000 abstract 2
239000006166 lysate Substances 0.000 abstract 2
239000007787 solid Substances 0.000 abstract 2
241000283690 Bos taurus Species 0.000 abstract 1
241000588724 Escherichia coli Species 0.000 abstract 1
241000287828 Gallus gallus Species 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
239000007853 buffer solution Substances 0.000 abstract 1
210000002421 cell wall Anatomy 0.000 abstract 1
230000001413 cellular effect Effects 0.000 abstract 1
238000005119 centrifugation Methods 0.000 abstract 1
239000012141 concentrate Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
239000002198 insoluble material Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000011236 particulate material Substances 0.000 abstract 1
239000012465 retentate Substances 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
238000000527 sonication Methods 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK198503779A 1984-08-27 1985-08-20 Fremgangsmåde til fremstilling af væksthormoner DK174889B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US64443584A	1984-08-27	1984-08-27
US64443584		1984-08-27
US73445085A	1985-05-15	1985-05-15
US73445085		1985-05-15

Publications (3)

Publication Number	Publication Date
DK377985D0 DK377985D0 (da)	1985-08-20
DK377985A true DK377985A (da)	1986-02-28
DK174889B1 DK174889B1 (da)	2004-01-19

Family

ID=27094481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198503779A DK174889B1 (da)	1984-08-27	1985-08-20	Fremgangsmåde til fremstilling af væksthormoner

Country Status (16)

Country	Link
EP (1)	EP0173215B1 (da)
JP (1)	JPH0655154B2 (da)
KR (1)	KR930009336B1 (da)
AT (1)	ATE90389T1 (da)
AU (1)	AU589569B2 (da)
CA (1)	CA1267615A (da)
DE (1)	DE3587391T2 (da)
DK (1)	DK174889B1 (da)
ES (1)	ES8606496A1 (da)
GR (1)	GR852031B (da)
HK (1)	HK147695A (da)
HU (1)	HU201806B (da)
IE (1)	IE58860B1 (da)
IL (1)	IL76191A (da)
NZ (1)	NZ213153A (da)
PT (1)	PT81012B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4342832A (en) *	1979-07-05	1982-08-03	Genentech, Inc.	Method of constructing a replicable cloning vehicle having quasi-synthetic genes
CA1272144A (en) *	1984-06-29	1990-07-31	Tamio Mizukami	Fish growth hormone polypeptide
US4748234A (en) *	1985-06-26	1988-05-31	Cetus Corporation	Process for recovering refractile bodies containing heterologous proteins from microbial hosts
US5064943A (en) *	1988-12-16	1991-11-12	American Cyanamid Company	Method for solubilization and naturation of somatotropin
US4975529A (en) *	1989-08-18	1990-12-04	Monsanto Company	Method of folding somatotropins
ATE113060T1 (de) *	1989-12-05	1994-11-15	American Cyanamid Co	Methode zur auflösung und naturation von somatotropin unter verwendung von einer niedrigen harnstoffkonzentration.
KR940005594B1 (ko) *	1991-12-24	1994-06-21	주식회사 럭키	양 성장 호르몬의 정제방법
KR100229420B1 (ko) *	1992-05-09	1999-11-01	성재갑	대장균에서 발현된 닭 성장 호르몬의 정제 방법
US5437986A (en) *	1994-06-22	1995-08-01	Schering Corporation	Extraction of heterologous insoluble proteins from bacteria
KR970061918A (ko) *	1996-02-22	1997-09-12	성재갑	대장균에서 발현된 유전자 재조합 닭 성장 호르몬의 정제방법
EP1149160B1 (en)	1999-01-25	2006-04-19	Novozymes A/S	Recovery of a protein at high ph
US6566329B1 (en)	1999-06-28	2003-05-20	Novo Nordisk A/S	Freeze-dried preparation of human growth hormone
WO2013183948A1 (ko)	2012-06-05	2013-12-12	씨제이제일제당 (주)	고당화된 지속형 인간 성장호르몬 단백질 및 이의 제조방법
KR101460266B1 (ko) *	2012-06-05	2014-11-11	씨제이헬스케어 주식회사	신규한 지속형 인간 성장호르몬의 정제 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0111814A3 (en) *	1982-12-16	1985-08-14	Mgi Pharma, Inc.	The cloning and expression of nucleotide sequences encoding bovine growth hormone
GR79124B (da) *	1982-12-22	1984-10-02	Genentech Inc
BG49718A3 (bg) *	1983-07-15	1992-01-15	Bio- Technology General Corp	Метод за получаване на полипептид със супероксиддисмутазна активност
CA1340597C (en) *	1984-08-27	1999-06-22	Haim Aviv	Expression vectors containing pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods

1985
- 1985-08-15 CA CA000488765A patent/CA1267615A/en not_active Expired - Lifetime
- 1985-08-16 KR KR1019850005918A patent/KR930009336B1/ko not_active Expired - Lifetime
- 1985-08-16 AU AU46268/85A patent/AU589569B2/en not_active Expired
- 1985-08-19 DE DE85110371T patent/DE3587391T2/de not_active Expired - Lifetime
- 1985-08-19 EP EP85110371A patent/EP0173215B1/en not_active Expired - Lifetime
- 1985-08-19 AT AT85110371T patent/ATE90389T1/de not_active IP Right Cessation
- 1985-08-20 DK DK198503779A patent/DK174889B1/da not_active IP Right Cessation
- 1985-08-20 NZ NZ213153A patent/NZ213153A/xx unknown
- 1985-08-22 JP JP60184984A patent/JPH0655154B2/ja not_active Expired - Fee Related
- 1985-08-22 GR GR852031A patent/GR852031B/el unknown
- 1985-08-22 HU HU853203A patent/HU201806B/hu unknown
- 1985-08-23 ES ES546395A patent/ES8606496A1/es not_active Expired
- 1985-08-23 PT PT81012A patent/PT81012B/pt unknown
- 1985-08-26 IL IL76191A patent/IL76191A/xx not_active IP Right Cessation
- 1985-08-26 IE IE209285A patent/IE58860B1/en not_active IP Right Cessation
1995
- 1995-09-14 HK HK147695A patent/HK147695A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT81012B (pt)	1987-09-18
HUT38398A (en)	1986-05-28
HU201806B (en)	1990-12-28
DK174889B1 (da)	2004-01-19
JPH0655154B2 (ja)	1994-07-27
KR870002258A (ko)	1987-03-30
EP0173215A2 (en)	1986-03-05
ATE90389T1 (de)	1993-06-15
AU589569B2 (en)	1989-10-19
IL76191A (en)	1990-12-23
DE3587391T2 (de)	1994-01-13
IL76191A0 (en)	1985-12-31
GR852031B (da)	1985-12-30
EP0173215A3 (en)	1987-11-25
CA1267615A (en)	1990-04-10
HK147695A (en)	1995-09-22
JPS6193128A (ja)	1986-05-12
NZ213153A (en)	1988-07-28
IE852092L (en)	1986-02-27
KR930009336B1 (ko)	1993-09-27
ES8606496A1 (es)	1986-04-16
ES546395A0 (es)	1986-04-16
DE3587391D1 (de)	1993-07-15
AU4626885A (en)	1986-03-06
PT81012A (en)	1985-09-01
IE58860B1 (en)	1993-11-17
EP0173215B1 (en)	1993-06-09
DK377985D0 (da)	1985-08-20

Legal Events

Date	Code	Title	Description
2005-09-05	PUP	Patent expired

Publication	Publication Date	Title
AU589569B2 (en)	1989-10-19	Method for recovering purified growth hormones from genetically engineered microorganisms
AU575304B2 (en)	1988-07-28	Removal of impurities from human leukocyte interferon
DE69012579D1 (de)	1994-10-20	Verfahren zur rückgewinnung rekombinanter proteine unter verwendung von flockungsmitteln.
IE852141L (en)	1986-03-01	Harvesting recombinant polypeptides
GR3007446T3 (da)	1993-07-30
ZA9610233B (en)	1997-06-24	Process of preparing an organic acid
AU7671087A (en)	1988-02-11	Method for purifying and isolating two ionic forms of somatomedin C
KR870700092A (ko)	1987-02-28	D-아미노산옥시다아제와 그의 단리방법
EP0069995A3 (en)	1983-07-20	Process for preparing a mixture of bee pollen having an improved resorption capacity, and a hyposensibilizing mixture of bee pollen
GB1423265A (en)	1976-02-04	Production of orgotein-containing protein concentrates from blood
JPS5625114A (en)	1981-03-10	Preparation of human gamma globulin
SPRENGER et al.	1972	Alteration of red cell membrane subunit pattern after pronase treatment
Katsuyama et al.	1984	Integral multilayer analytical element for the assay of total protein
Malick et al.	1984	Production of single cell protein material
JPS6456700A (en)	1989-03-03	Concentration of hemin