HK147695A - Method for recovering purified growth hormones from genetically engineered microorganisms - Google Patents

Method for recovering purified growth hormones from genetically engineered microorganisms Download PDF

Info

Publication number
HK147695A
HK147695A HK147695A HK147695A HK147695A HK 147695 A HK147695 A HK 147695A HK 147695 A HK147695 A HK 147695A HK 147695 A HK147695 A HK 147695A HK 147695 A HK147695 A HK 147695A
Authority
HK
Hong Kong
Prior art keywords
analog
hormone
suspension
ultrafiltration
liquid
Prior art date
Application number
HK147695A
Other languages
German (de)
English (en)
French (fr)
Inventor
Bartfeld Daniel
Blumberg Shmaryahu
Gorecki Marian
Hadary Dan
Zeevi Menachem
Original Assignee
Bio-Technology General Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio-Technology General Corporation filed Critical Bio-Technology General Corporation
Publication of HK147695A publication Critical patent/HK147695A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
HK147695A 1984-08-27 1995-09-14 Method for recovering purified growth hormones from genetically engineered microorganisms HK147695A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64443584A 1984-08-27 1984-08-27
US73445085A 1985-05-15 1985-05-15

Publications (1)

Publication Number Publication Date
HK147695A true HK147695A (en) 1995-09-22

Family

ID=27094481

Family Applications (1)

Application Number Title Priority Date Filing Date
HK147695A HK147695A (en) 1984-08-27 1995-09-14 Method for recovering purified growth hormones from genetically engineered microorganisms

Country Status (16)

Country Link
EP (1) EP0173215B1 (da)
JP (1) JPH0655154B2 (da)
KR (1) KR930009336B1 (da)
AT (1) ATE90389T1 (da)
AU (1) AU589569B2 (da)
CA (1) CA1267615A (da)
DE (1) DE3587391T2 (da)
DK (1) DK174889B1 (da)
ES (1) ES8606496A1 (da)
GR (1) GR852031B (da)
HK (1) HK147695A (da)
HU (1) HU201806B (da)
IE (1) IE58860B1 (da)
IL (1) IL76191A (da)
NZ (1) NZ213153A (da)
PT (1) PT81012B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
CA1272144A (en) * 1984-06-29 1990-07-31 Tamio Mizukami Fish growth hormone polypeptide
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
US5064943A (en) * 1988-12-16 1991-11-12 American Cyanamid Company Method for solubilization and naturation of somatotropin
US4975529A (en) * 1989-08-18 1990-12-04 Monsanto Company Method of folding somatotropins
ATE113060T1 (de) * 1989-12-05 1994-11-15 American Cyanamid Co Methode zur auflösung und naturation von somatotropin unter verwendung von einer niedrigen harnstoffkonzentration.
KR940005594B1 (ko) * 1991-12-24 1994-06-21 주식회사 럭키 양 성장 호르몬의 정제방법
KR100229420B1 (ko) * 1992-05-09 1999-11-01 성재갑 대장균에서 발현된 닭 성장 호르몬의 정제 방법
US5437986A (en) * 1994-06-22 1995-08-01 Schering Corporation Extraction of heterologous insoluble proteins from bacteria
KR970061918A (ko) * 1996-02-22 1997-09-12 성재갑 대장균에서 발현된 유전자 재조합 닭 성장 호르몬의 정제방법
EP1149160B1 (en) 1999-01-25 2006-04-19 Novozymes A/S Recovery of a protein at high ph
US6566329B1 (en) 1999-06-28 2003-05-20 Novo Nordisk A/S Freeze-dried preparation of human growth hormone
US9902753B2 (en) 2012-06-05 2018-02-27 Cj Healthcare Corporation Method of purifying a long-acting human growth hormone
KR101460266B1 (ko) * 2012-06-05 2014-11-11 씨제이헬스케어 주식회사 신규한 지속형 인간 성장호르몬의 정제 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
GR79124B (da) * 1982-12-22 1984-10-02 Genentech Inc
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
CA1340597C (en) * 1984-08-27 1999-06-22 Haim Aviv Expression vectors containing pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods

Also Published As

Publication number Publication date
EP0173215A2 (en) 1986-03-05
CA1267615A (en) 1990-04-10
IL76191A0 (en) 1985-12-31
DK377985A (da) 1986-02-28
HU201806B (en) 1990-12-28
NZ213153A (en) 1988-07-28
PT81012B (pt) 1987-09-18
AU4626885A (en) 1986-03-06
ES546395A0 (es) 1986-04-16
PT81012A (en) 1985-09-01
DK174889B1 (da) 2004-01-19
HUT38398A (en) 1986-05-28
ATE90389T1 (de) 1993-06-15
GR852031B (da) 1985-12-30
DE3587391D1 (de) 1993-07-15
IE852092L (en) 1986-02-27
DE3587391T2 (de) 1994-01-13
JPH0655154B2 (ja) 1994-07-27
IL76191A (en) 1990-12-23
EP0173215A3 (en) 1987-11-25
IE58860B1 (en) 1993-11-17
KR870002258A (ko) 1987-03-30
DK377985D0 (da) 1985-08-20
JPS6193128A (ja) 1986-05-12
ES8606496A1 (es) 1986-04-16
KR930009336B1 (ko) 1993-09-27
AU589569B2 (en) 1989-10-19
EP0173215B1 (en) 1993-06-09

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Effective date: 20050818