DK377986A - Farmaceutiske praeparater indeholdende en stabil fast molekylaer dispersion af 2-aryl-pyrazolo-quinoliner i polyvinylpyrrolidon - Google Patents

Farmaceutiske praeparater indeholdende en stabil fast molekylaer dispersion af 2-aryl-pyrazolo-quinoliner i polyvinylpyrrolidon Download PDF

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Publication number
DK377986A
DK377986A DK377986A DK377986A DK377986A DK 377986 A DK377986 A DK 377986A DK 377986 A DK377986 A DK 377986A DK 377986 A DK377986 A DK 377986A DK 377986 A DK377986 A DK 377986A
Authority
DK
Denmark
Prior art keywords
polyvinylpyrrolidon
aryl
pharmaceutical preparations
preparations containing
stable solid
Prior art date
Application number
DK377986A
Other languages
Danish (da)
English (en)
Other versions
DK377986D0 (da
Inventor
Lewis J Leeson
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK377986D0 publication Critical patent/DK377986D0/da
Publication of DK377986A publication Critical patent/DK377986A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK377986A 1985-08-08 1986-08-07 Farmaceutiske praeparater indeholdende en stabil fast molekylaer dispersion af 2-aryl-pyrazolo-quinoliner i polyvinylpyrrolidon DK377986A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76348985A 1985-08-08 1985-08-08

Publications (2)

Publication Number Publication Date
DK377986D0 DK377986D0 (da) 1986-08-07
DK377986A true DK377986A (da) 1987-02-09

Family

ID=25067966

Family Applications (1)

Application Number Title Priority Date Filing Date
DK377986A DK377986A (da) 1985-08-08 1986-08-07 Farmaceutiske praeparater indeholdende en stabil fast molekylaer dispersion af 2-aryl-pyrazolo-quinoliner i polyvinylpyrrolidon

Country Status (3)

Country Link
EP (1) EP0214092A1 (de)
JP (1) JPS6263519A (de)
DK (1) DK377986A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
GB9716345D0 (en) * 1997-08-01 1997-10-08 Merck Sharp & Dohme Therapeutic compounds
NZ504834A (en) * 1997-12-22 2001-12-21 Schering Corp Tricyclic amide molecular dispersion composition with enhanced bioavailability
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
DE19930454A1 (de) * 1999-07-02 2001-01-04 Knoll Ag Feste Paroxetin enthaltende Zubereitungen
JP2010529144A (ja) 2007-06-08 2010-08-26 ヘリコン・セラピューティクス・インコーポレーテッド 治療用ピラゾロキノリン尿素誘導体
ATE544344T1 (de) 2007-06-08 2012-02-15 Helicon Therapeutics Inc Therapeutische pyrazolochinolinderivate
KR20100036306A (ko) 2007-06-08 2010-04-07 헬리콘 테라퓨틱스 인코퍼레이티드 치료용 피라졸로나프티리딘 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES403326A1 (es) * 1971-06-04 1975-05-01 Boehringer Mannheim Gmbh Procedimiento para la granulacion de masas para tabletas enforma de polvo.
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
US4312870A (en) * 1979-06-21 1982-01-26 Ciba-Geigy Corporation Pyrazoloquinolines
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4459298A (en) * 1982-09-28 1984-07-10 Ciba-Geigy Corporation Method of suppressing appetite

Also Published As

Publication number Publication date
EP0214092A1 (de) 1987-03-11
DK377986D0 (da) 1986-08-07
JPS6263519A (ja) 1987-03-20

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment