DK381283D0 - Fremgangsmade til fremstilling af thiazinderivater - Google Patents

Fremgangsmade til fremstilling af thiazinderivater

Info

Publication number: DK381283D0
Authority: DK; Denmark
Prior art keywords: procedure; preparation; thiazine derivatives; thiazine; salts
Prior art date: 1982-09-09

Application number

DK3812/83A

Other languages

English (en)

Other versions

DK155009B (da

DK155009C (da

DK381283A (da

Inventor

Rudolf Pfister

Paul Zeller

Dieter Binder

Otto Hromatka

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-09

Filing date

1983-08-19

Publication date

1983-08-19

1983-08-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1983-08-19 Publication of DK381283D0 publication Critical patent/DK381283D0/da

1984-03-10 Publication of DK381283A publication Critical patent/DK381283A/da

1989-01-23 Publication of DK155009B publication Critical patent/DK155009B/da

1989-06-05 Application granted granted Critical

1989-06-05 Publication of DK155009C publication Critical patent/DK155009C/da

Links

150000004897 thiazines Chemical class 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 2
FHZDNBBQTQLLLV-UHFFFAOYSA-N 4-hydroxy-2-methyl-1,1-dioxo-n-pyridin-2-yl-6-(trifluoromethyl)thieno[2,3-e]thiazine-3-carboxamide Chemical compound OC=1C=2SC(C(F)(F)F)=CC=2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 FHZDNBBQTQLLLV-UHFFFAOYSA-N 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000003356 anti-rheumatic effect Effects 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000003285 pharmacodynamic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyridine Compounds (AREA)

DK381283A 1982-09-09 1983-08-19 Analogifremgangsmaade til fremstilling af thienooe2,3-eaa-1,2-thiazin-1,1-dioxidderivat eller farmaceutisk tolerable salte heraf samt udgangsmateriale til brug ved fremgangsmaaden DK155009C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH537782		1982-09-09
CH537782		1982-09-09

Publications (4)

Publication Number	Publication Date
DK381283D0 true DK381283D0 (da)	1983-08-19
DK381283A DK381283A (da)	1984-03-10
DK155009B DK155009B (da)	1989-01-23
DK155009C DK155009C (da)	1989-06-05

Family

ID=4292544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK381283A DK155009C (da)	1982-09-09	1983-08-19	Analogifremgangsmaade til fremstilling af thienooe2,3-eaa-1,2-thiazin-1,1-dioxidderivat eller farmaceutisk tolerable salte heraf samt udgangsmateriale til brug ved fremgangsmaaden

Country Status (13)

Country	Link
US (1)	US4544655A (da)
EP (1)	EP0103142B1 (da)
JP (1)	JPS5967292A (da)
AT (1)	ATE26720T1 (da)
AU (1)	AU560973B2 (da)
CA (1)	CA1217187A (da)
DE (1)	DE3371082D1 (da)
DK (1)	DK155009C (da)
IE (1)	IE55942B1 (da)
IL (1)	IL69628A (da)
NZ (1)	NZ205475A (da)
PH (1)	PH19692A (da)
ZA (1)	ZA836546B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ226477A (en) *	1987-10-29	1990-07-26	Cl Pharma	Substituted thieno (2,3-e)-1,2 thiazine derivatives and pharmaceutical compositions
ATA39088A (de)	1988-02-18	1990-06-15	Binder Dieter Dr	Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung
AT399880B (de) *	1992-07-03	1995-08-25	Chem Pharm Forsch Gmbh	Neue thienothiazinderivate, verfahren zu ihrer herstellung und ihre verwendung
EP0658559A1 (de) *	1993-12-14	1995-06-21	Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.	Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren
US8329924B2 (en) *	2001-06-11	2012-12-11	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections
AU2002344854B2 (en) *	2001-06-11	2008-11-06	Vertex Pharmaceuticals (Canada) Incorporated	Thiophene derivatives as antiviral agents for flavivirus infection
AT413944B (de)	2003-05-27	2006-07-15	Binder Eva Dkfm	Verwendung von oxicam-verbindungen
US7109232B2 (en) *	2004-03-08	2006-09-19	Simpson Biotech Co., Ltd.	Compounds from Antrodia camphorata having anti-inflammatory and anti-tumor activity
CA2746055C (en) *	2008-12-16	2016-12-13	Sunovion Pharmaceuticals Inc.	Triple reuptake inhibitors and methods of their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1066711A (en) *	1974-08-26	1979-11-20	Hoffmann-La Roche Limited	Thiophene derivatives
IL47877A (en) *	1974-08-26	1978-10-31	Sparamedica Ag	Thienothiazine carboxamide derivatives,their manufacture and pharmaceutical compositions containing them
AU518216B2 (en) *	1977-09-06	1981-09-17	Hafslund Nycomed Pharma Aktiengesellschaft	Thienothiazine derivatives

1983
- 1983-08-04 AT AT83107677T patent/ATE26720T1/de not_active IP Right Cessation
- 1983-08-04 DE DE8383107677T patent/DE3371082D1/de not_active Expired
- 1983-08-04 EP EP83107677A patent/EP0103142B1/de not_active Expired
- 1983-08-12 CA CA000434462A patent/CA1217187A/en not_active Expired
- 1983-08-19 DK DK381283A patent/DK155009C/da not_active IP Right Cessation
- 1983-08-31 US US06/528,341 patent/US4544655A/en not_active Expired - Fee Related
- 1983-09-02 IL IL69628A patent/IL69628A/xx unknown
- 1983-09-02 NZ NZ205475A patent/NZ205475A/xx unknown
- 1983-09-02 ZA ZA836546A patent/ZA836546B/xx unknown
- 1983-09-06 JP JP58162711A patent/JPS5967292A/ja active Pending
- 1983-09-08 IE IE2108/83A patent/IE55942B1/xx unknown
- 1983-09-09 PH PH29520A patent/PH19692A/en unknown
- 1983-09-09 AU AU19007/83A patent/AU560973B2/en not_active Ceased

Also Published As

Publication number	Publication date
DK155009B (da)	1989-01-23
PH19692A (en)	1986-06-13
IL69628A0 (en)	1983-12-30
IE832108L (en)	1984-03-09
ATE26720T1 (de)	1987-05-15
IL69628A (en)	1986-09-30
IE55942B1 (en)	1991-02-27
CA1217187A (en)	1987-01-27
AU1900783A (en)	1984-03-15
DK155009C (da)	1989-06-05
EP0103142B1 (de)	1987-04-22
US4544655A (en)	1985-10-01
AU560973B2 (en)	1987-04-30
JPS5967292A (ja)	1984-04-16
NZ205475A (en)	1985-08-30
EP0103142A1 (de)	1984-03-21
ZA836546B (en)	1984-04-25
DK381283A (da)	1984-03-10
DE3371082D1 (de)	1987-05-27

Legal Events

Date	Code	Title	Description
1992-04-21	PBP	Patent lapsed

Publication	Publication Date	Title
HK1085A (en)	1985-01-11	3-carbamoyl-4-hydroxy-2h-thieno-1,2-thiazine-1,1-dioxide derivatives
ES477695A1 (es)	1979-10-16	Un procedimiento para preparar derivados de deshidrociclici-minoacidos.
NO904377D0 (no)	1990-10-10	Tricykliske karbapenemforbindelser.
DK381283A (da)	1984-03-10	Fremgangsmaade til fremstilling af thiazinderivater
SE7707341L (sv)	1978-02-13	4-hydroxifenylalkanolamin-derivat och forfarande for framstellning derav
FI882873A0 (fi)	1988-06-16	Tiofenderivat och foerfarande foer dess framstaellning.
NO890440L (no)	1990-01-15	Fremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater.
DE69911176D1 (de)	2003-10-16	Spiropiperidin-derivate
NO940018D0 (no)	1994-01-04	Fremgangsmaate for fremstilling av svovelholdige imidazolderivater
FR2378752A1 (fr)	1978-08-25	Nouveaux diurethanes utiles comme herbicides
ES466192A1 (es)	1978-10-16	Procedimiento para la obtencion de derivados de la isoqui- noleina.
DK159110C (da)	1991-02-11	4h-benzo(4,5)cyclohepta(1,2-b)thiophenderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende derivaterne
MX15697A (es)	1993-12-01	Derivados heterotetraciclicos de lactama y procesopara su preparacion
DK316589A (da)	1989-06-26	Substituerede azacyclohexylderivater af rifamyciner
JPS57131775A (en)	1982-08-14	Novel benzothiazine derivative, its prepatation and medicinal composition contaububg the sane
IE42711L (en)	1976-11-30	THIENO (3,2-c) PYRIDINE DERIVATIVES
IE43583L (en)	1977-01-30	11-oxodibenzoxepinealkanoic acids and esters.
SE8003476L (sv)	1980-11-10	Isokinolinderivat
GB2018770A (en)	1979-10-24	Hexahydro-1-mercaptoacyl-1H- azepine-2-carboxylic acids and esters
JPS5634674A (en)	1981-04-06	Isoxazolin-3-one derivative
ES8105713A1 (es)	1981-05-16	Un procedimiento para la preparacion de los enatiomeros levogiro y dextrogiro de la 1-ciclopropil-metil-4-(3-metoxi-5h- dibenzo (a,d) ciclohepten-5-iliden) piperidina