DK3826662T5 - Fremgangsmåde til anvendelse af en GIP/GLP1-co-agonist til diabetes - Google Patents

Fremgangsmåde til anvendelse af en GIP/GLP1-co-agonist til diabetes Download PDF

Info

Publication number
DK3826662T5
DK3826662T5 DK19749938.7T DK19749938T DK3826662T5 DK 3826662 T5 DK3826662 T5 DK 3826662T5 DK 19749938 T DK19749938 T DK 19749938T DK 3826662 T5 DK3826662 T5 DK 3826662T5
Authority
DK
Denmark
Prior art keywords
glp1
gip
agonist
diabetes
Prior art date
Application number
DK19749938.7T
Other languages
English (en)
Other versions
DK3826662T3 (da
Inventor
Jorge Alsina-Fernandez
Over Cabrera
Tamer Coskun
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK3826662T3 publication Critical patent/DK3826662T3/da
Publication of DK3826662T5 publication Critical patent/DK3826662T5/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
DK19749938.7T 2018-07-23 2019-07-22 Fremgangsmåde til anvendelse af en GIP/GLP1-co-agonist til diabetes DK3826662T5 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862702180P 2018-07-23 2018-07-23
US201862730562P 2018-09-13 2018-09-13
US201862740640P 2018-10-03 2018-10-03
PCT/US2019/042824 WO2020023388A1 (en) 2018-07-23 2019-07-22 Method of using a gip/glp1 co-agonist for diabetes

Publications (2)

Publication Number Publication Date
DK3826662T3 DK3826662T3 (da) 2024-09-30
DK3826662T5 true DK3826662T5 (da) 2025-03-24

Family

ID=67544389

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19749938.7T DK3826662T5 (da) 2018-07-23 2019-07-22 Fremgangsmåde til anvendelse af en GIP/GLP1-co-agonist til diabetes

Country Status (25)

Country Link
US (2) US12295987B2 (da)
EP (2) EP4450127A3 (da)
JP (3) JP7620601B2 (da)
KR (2) KR20240095310A (da)
CN (2) CN112469431A (da)
AU (2) AU2019309798A1 (da)
BR (1) BR112020026020A2 (da)
CA (1) CA3107108A1 (da)
DK (1) DK3826662T5 (da)
ES (1) ES2993282T3 (da)
FI (1) FI3826662T5 (da)
HR (1) HRP20241479T2 (da)
HU (1) HUE069270T2 (da)
IL (2) IL280159B2 (da)
LT (1) LT3826662T (da)
MA (1) MA53378A (da)
MX (2) MX2021000792A (da)
PL (1) PL3826662T3 (da)
PT (1) PT3826662T (da)
RS (1) RS66110B9 (da)
SG (1) SG11202100116TA (da)
SI (1) SI3826662T1 (da)
UA (1) UA129947C2 (da)
WO (1) WO2020023388A1 (da)
ZA (1) ZA202212500B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI744579B (zh) * 2017-12-21 2021-11-01 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
TW202140058A (zh) 2020-01-30 2021-11-01 美商美國禮來大藥廠 提派肽(tirzepatide)之治療用途
TW202216746A (zh) 2020-06-22 2022-05-01 印度商太陽製藥工業有限公司 長效型glp-1/gip雙重促效劑
AU2021312323A1 (en) 2020-07-22 2023-02-02 Novo Nordisk A/S Co-agonists at GLP-1 and GIP receptors suitable for oral delivery
BR112023003668A2 (pt) 2020-10-17 2023-04-25 Sun Pharmaceutical Ind Ltd Agonistas duplos de glp-1/gip
JP2024508745A (ja) * 2021-02-17 2024-02-28 イーライ リリー アンド カンパニー Gip/glp1デュアルアゴニスト治療方法
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
WO2024252366A1 (en) 2023-06-09 2024-12-12 Sun Pharmaceutical Industries Limited Glp-1/gip dual, glp-1/gcg dual and glp-1/gip/gcg triple receptor agonists
CN116854805B (zh) * 2023-09-05 2023-12-15 杭州湃肽生化科技有限公司 替尔泊肽的制备方法
WO2026046202A1 (zh) * 2024-08-26 2026-03-05 博瑞生物医药(苏州)股份有限公司 Glp-1/gip肽或含有其的药物组合物的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2556466T3 (es) * 2011-05-13 2016-01-18 Sanofi-Aventis Deutschland Gmbh Lixisenatida y metformina para el tratamiento de la diabetes tipo 2
NZ702333A (en) 2012-05-03 2017-06-30 Zealand Pharma As Gip-glp-1 dual agonist compounds and methods
KR20210086717A (ko) 2013-05-02 2021-07-08 노보 노르디스크 에이/에스 Glp-1 화합물의 경구 투여
WO2015022420A1 (en) * 2013-08-16 2015-02-19 Medimmune Limited Gip and glp-1 receptor dual-agonists for the treatment of diabetes
AU2014345569B2 (en) 2013-11-06 2020-08-13 Zealand Pharma A/S GIP-GLP-1 dual agonist compounds and methods
JO3575B1 (ar) * 2015-01-09 2020-07-05 Lilly Co Eli مركبات مساعد مشترك من gip وglp-1
US20170112897A1 (en) * 2015-10-23 2017-04-27 Cedars-Sinai Medical Center Methods for treating brain insulin resistance
TWI622596B (zh) * 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
TWI705820B (zh) 2018-06-22 2020-10-01 美商美國禮來大藥廠 Gip/glp1促效劑組合物
TWI735917B (zh) * 2018-07-23 2021-08-11 美商美國禮來大藥廠 Gip/glp1共促效劑化合物

Also Published As

Publication number Publication date
CN119499352A (zh) 2025-02-25
IL308674A (en) 2024-01-01
ES2993282T3 (en) 2024-12-26
FI3826662T5 (fi) 2025-03-28
MA53378A (fr) 2021-06-02
ZA202212500B (en) 2024-10-30
SI3826662T1 (sl) 2025-01-31
EP4450127A3 (en) 2025-01-01
AU2024202616A1 (en) 2024-07-11
JP2024056852A (ja) 2024-04-23
JP2021530544A (ja) 2021-11-11
CN112469431A (zh) 2021-03-09
US20250241995A1 (en) 2025-07-31
PT3826662T (pt) 2024-10-30
HRP20241479T2 (hr) 2025-03-14
US12295987B2 (en) 2025-05-13
MX2025007846A (es) 2025-08-01
RS66110B9 (sr) 2025-05-30
HUE069270T2 (hu) 2025-02-28
KR20240095310A (ko) 2024-06-25
EP3826662B1 (en) 2024-09-11
CA3107108A1 (en) 2020-01-30
UA129947C2 (uk) 2025-09-24
EP4450127A2 (en) 2024-10-23
JP2022177118A (ja) 2022-11-30
IL280159A (en) 2021-03-01
MX2021000792A (es) 2021-06-15
LT3826662T (lt) 2024-11-25
JP2025063146A (ja) 2025-04-15
RS66110B1 (sr) 2024-11-29
DK3826662T3 (da) 2024-09-30
US12453758B2 (en) 2025-10-28
SG11202100116TA (en) 2021-02-25
EP3826662A1 (en) 2021-06-02
EP3826662B9 (en) 2025-02-19
JP7620601B2 (ja) 2025-01-23
BR112020026020A2 (pt) 2021-03-23
US20230293638A1 (en) 2023-09-21
IL280159B2 (en) 2024-05-01
WO2020023388A1 (en) 2020-01-30
FI3826662T3 (fi) 2024-11-20
AU2019309798A1 (en) 2021-02-11
HRP20241479T1 (hr) 2025-01-03
ES2993282T9 (en) 2025-03-13
IL280159B1 (en) 2024-01-01
PL3826662T3 (pl) 2025-01-20
KR20210024081A (ko) 2021-03-04

Similar Documents

Publication Publication Date Title
DK3826662T3 (da) Fremgangsmåde til anvendelse af en GIP/GLP1-co-agonist til diabetes
IL279827A (en) Gip/glp1 co-agonist compounds
IL284446A (en) Process for preparing a gip/glp1 dual agonist
DK3490398T3 (da) Fremgangsmåde til anvendelse af et sæt vippeextensions
SG11202100112YA (en) Methods of using a gip/glp1 co-agonist for therapy
DK3898933T3 (da) Fremgangsmåde til fremstilling af et funktionelt gærproteinkoncentrat
DK3618758T4 (da) Fremgangsmåde til konstruktion af en dental komponent
DK4206308T3 (da) Fremgangsmåde til behandling af lipidmaterialer
DK3565276T3 (da) Fremgangsmåde til drift af et høreapparat og høreapparat
DK3741701T3 (da) Fremgangsmåde til fremstilling af et metallisk dåselåg
DK3367910T3 (da) Fremgangsmåde til anvendelse af en sondeafdækning
DK3439093T3 (da) Redox-flow-batteri og fremgangsmåde til drift af et redox-flow-batteri
DK3579580T3 (da) Fremgangsmåde til fremstilling af en komponent af et høreapparat
DK3774745T3 (da) Krystal af en oxazolforbindelse
DK3391665T3 (da) Metode til anvendelse af et høreapparat
DK3535226T3 (da) Fremgangsmåde til påføring af et ikke-portland-cement-baseret materiale
DK3543954T3 (da) Fremgangsmåde til behandling af en video
DK3996673T3 (da) En metode til fremstilling af en geldannende sammensætning
DK3919499T3 (da) Nye polymorfer af en triazolopyrazinforbindelse og metode til forberedelse
IL289634A (en) Novel reprogramming method
DK3900258T3 (da) Fremgangsmåde til overvågning af et fysisk objekts integritet
DK3553212T3 (da) Fremgangsmåde til fremstilling af en krystal af granattypen
DK3649305T3 (da) Fremgangsmåde til fremstilling af en betonforskalling til en komponent og anvendelse af en betonforskalling
IL282108A (en) Preparation method for efinaconazole
DK4010331T3 (da) En fremgangsmåde til fremstilling af ivosidenib og en mellemprodukt deraf