DK3858977T5 - Stamme til forebyggelse og behandling af stofskiftesygdomme, og brugen heraf - Google Patents

Stamme til forebyggelse og behandling af stofskiftesygdomme, og brugen heraf Download PDF

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Publication number
DK3858977T5
DK3858977T5 DK19864901.4T DK19864901T DK3858977T5 DK 3858977 T5 DK3858977 T5 DK 3858977T5 DK 19864901 T DK19864901 T DK 19864901T DK 3858977 T5 DK3858977 T5 DK 3858977T5
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Denmark
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strain
prevention
treatment
metabolic diseases
metabolic
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DK19864901.4T
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English (en)
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DK3858977T3 (da
Inventor
Bin Wen
Guang Ning
Xin Ma
Weiqing Wang
Hongjing Yu
Jie Hong
Ningyun Sun
Jiqiu Wang
Peijun Yin
Ruixin Liu
Yuan Gao
Shasha Wang
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Sph Sine Pharmaceutical Laboratories Co Ltd
Shanghai Inst Of Endocrine And Metabolic Diseases
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Application filed by Sph Sine Pharmaceutical Laboratories Co Ltd, Shanghai Inst Of Endocrine And Metabolic Diseases filed Critical Sph Sine Pharmaceutical Laboratories Co Ltd
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Publication of DK3858977T5 publication Critical patent/DK3858977T5/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK19864901.4T 2018-09-27 2019-09-25 Stamme til forebyggelse og behandling af stofskiftesygdomme, og brugen heraf DK3858977T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201811132882.1A CN110964650B (zh) 2018-09-27 2018-09-27 一种用于预防和治疗代谢疾病的菌株及其应用
PCT/CN2019/107757 WO2020063646A1 (zh) 2018-09-27 2019-09-25 一种用于预防和治疗代谢疾病的菌株及其应用

Publications (2)

Publication Number Publication Date
DK3858977T3 DK3858977T3 (da) 2024-03-18
DK3858977T5 true DK3858977T5 (da) 2024-08-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK19864901.4T DK3858977T5 (da) 2018-09-27 2019-09-25 Stamme til forebyggelse og behandling af stofskiftesygdomme, og brugen heraf

Country Status (9)

Country Link
US (1) US12036251B2 (da)
EP (1) EP3858977B1 (da)
KR (1) KR102662155B1 (da)
CN (1) CN110964650B (da)
AU (1) AU2019346903C1 (da)
CA (1) CA3114471C (da)
DK (1) DK3858977T5 (da)
ES (1) ES2974171T3 (da)
WO (1) WO2020063646A1 (da)

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CN111228315A (zh) * 2020-02-27 2020-06-05 上海上药信谊药厂有限公司 抗肿瘤组合物
EP4560007A3 (en) * 2020-04-03 2025-08-13 International N&H Denmark ApS Compositions for metabolic health
CN112342154B (zh) * 2020-09-03 2022-08-05 上海上药信谊药厂有限公司 用于预防和治疗女性生殖道炎症的益生菌
US20230381246A1 (en) * 2020-10-19 2023-11-30 Duke University Genetically diverse akkermansia strains and methods of using same
BE1028339B1 (fr) * 2020-11-09 2021-12-21 A Mansia Biotech Composition comprenant de l'Akkermansia muciniphila et de l'extrait de thé vert
CN114451557A (zh) * 2020-11-10 2022-05-10 中国人民解放军南部战区总医院 Akk益生菌在制备防治中暑药物、食品或保健品中的应用
CN113322202B (zh) * 2021-05-31 2022-03-01 君维安(武汉)生命科技有限公司 一种阿克曼氏菌、其培养方法及其应用
BE1029496B1 (fr) * 2021-08-19 2023-01-16 The Akkermansia Company Composition comprenant de l'Akkermansia muciniphila pasteurisée pour le traitement ou la prévention des troubles de la contractilité intestinale, en particulier des troubles de l'amplitude de la contractilité duodénale
CN115804793B (zh) * 2022-06-08 2025-08-15 石家庄普维生物科技有限公司 嗜粘蛋白阿克曼菌在制备改善酒精性肝功能异常的组合物中的应用、组合物及应用
CN114949002B (zh) * 2022-06-08 2024-03-19 广州知易生物科技有限公司 嗜粘蛋白阿克曼菌在制备防治动脉粥样硬化的组合物中的应用
CN119818541A (zh) * 2022-06-08 2025-04-15 广州知易生物科技有限公司 嗜粘蛋白阿克曼菌在制备改善血糖水平的保健品组合物中的应用、组合物及其应用
CN116115647B (zh) * 2022-06-08 2024-12-20 广州知易生物科技有限公司 嗜粘蛋白阿克曼菌在制备改善代谢综合征的药物组合物或保健品组合物中的应用
CN115252651B (zh) * 2022-06-08 2024-06-07 广州知易生物科技有限公司 嗜粘蛋白阿克曼菌在制备防治高血压的组合物中的应用和含有其的组合物
CN114832019A (zh) * 2022-06-08 2022-08-02 广州知易生物科技有限公司 嗜粘蛋白阿克曼菌在制备防治肥胖症的药物组合物中的应用、组合物及其应用
CN114949004B (zh) * 2022-06-08 2024-04-26 广州知易生物科技有限公司 嗜黏蛋白阿克曼菌在制备防治高血脂的组合物中的应用及含有其的组合物
CN116236507B (zh) * 2023-02-27 2025-04-18 广州知易生物科技有限公司 嗜黏蛋白阿克曼氏菌在缓解和治疗精神分裂症中的应用
EP4444918A4 (en) * 2023-02-28 2025-11-26 Enterobiome Inc METHOD FOR PREDICTING THERAPEUTIC RESPONSE TO PHARMABIOTICS AND METHOD FOR TREATMENT OF VARIOUS DISEASES USING IT
CN116200312B (zh) * 2023-03-30 2023-08-22 广西爱生生命科技有限公司 一种抗氧化、减脂和抑制肿瘤生长的广西阿克曼氏菌及其产品与应用
CN116999519B (zh) * 2023-08-16 2024-11-12 江南大学 一种治疗高血脂症的药菌组合物及其制备方法和应用
CN117018039B (zh) * 2023-08-18 2025-04-01 善恩康生物科技(苏州)有限公司 Akkermansia muciniphila在制备预防、治疗和/或辅助治疗代谢疾病的产品中的应用
CN117903965A (zh) * 2023-12-05 2024-04-19 杭州微致生物科技有限公司 一种嗜黏蛋白阿克曼氏菌vb202及其应用
CN118178476A (zh) * 2024-04-03 2024-06-14 暨南大学附属第一医院(广州华侨医院) 阿克曼菌及其制剂在制备促进排便、排脂、减少肠道脂肪吸收的药物中的应用
CN118178478B (zh) * 2024-04-12 2025-01-24 善恩康生物科技(苏州)有限公司 Akkermansia muciniphila及其产品在糖尿病防治中的应用
CN118389344A (zh) * 2024-05-06 2024-07-26 微康益生菌(苏州)股份有限公司 一种提高嗜黏蛋白阿克曼菌产业化离心收率的制备方法及其应用
CN118272281B (zh) * 2024-06-04 2024-10-01 微康益生菌(苏州)股份有限公司 一种含有Akk11菌株的缓解高尿酸的益生菌剂及其应用

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WO2013130773A2 (en) * 2012-02-29 2013-09-06 Ethicon Endo-Surgery, Inc. Compositions of microbiota and methods related thereto
WO2014075745A1 (en) * 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders
US9846185B2 (en) * 2013-02-27 2017-12-19 Texas Instruments Incorporated Capacitive sensing
CN105106245A (zh) 2015-08-24 2015-12-02 上海交通大学医学院附属瑞金医院 Akkermansia muciniphila BAA-835菌株的应用
JP2018534277A (ja) * 2015-10-05 2018-11-22 シュヴァイツェリッシェ フォルシュングスインスティテュート フュア ホーフゲブリクスクリーマ ウント メディツィン イン ダヴォス 炎症性状態を治療するためのアッカーマンシア・ムシニフィラ(Akkermansia muciniphila)の使用
KR101809172B1 (ko) * 2016-07-11 2017-12-14 한국생명공학연구원 뮤신이 없는 배지에서 배양한 아커만시아 뮤시니필라 균주 또는 이의 배양액을 유효성분으로 함유하는 대사성 질환의 예방, 개선 또는 치료용 조성물
WO2018012834A1 (ko) * 2016-07-11 2018-01-18 한국생명공학연구원 퇴행성 뇌질환 또는 대사성 질환의 예방 또는 치료 효과를 가지는 아커만시아 뮤시니필라 균주 및 이의 용도
EP3551201A4 (en) * 2016-12-06 2020-06-24 Pendulum Therapeutics, Inc. METHODS AND COMPOSITIONS ASSOCIATED WITH INSULATED AND PURIFIED MICROBES
CN111093682B (zh) * 2017-12-08 2024-01-16 深圳华大生命科学研究院 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用
CN111944727B (zh) * 2020-08-24 2021-12-03 汤臣倍健股份有限公司 一种短双歧杆菌207-1及其应用

Also Published As

Publication number Publication date
CA3114471C (en) 2025-05-13
EP3858977A4 (en) 2022-06-01
US20220031769A1 (en) 2022-02-03
EP3858977A1 (en) 2021-08-04
EP3858977B1 (en) 2024-02-28
US12036251B2 (en) 2024-07-16
KR102662155B1 (ko) 2024-04-29
AU2019346903A1 (en) 2021-05-20
CN110964650B (zh) 2022-10-11
AU2019346903B2 (en) 2022-12-15
ES2974171T3 (es) 2024-06-26
WO2020063646A1 (zh) 2020-04-02
DK3858977T3 (da) 2024-03-18
CN110964650A (zh) 2020-04-07
KR20210069663A (ko) 2021-06-11
AU2019346903C1 (en) 2023-06-22
CA3114471A1 (en) 2020-04-02

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