DK388588A - N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse - Google Patents

N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK388588A
DK388588A DK388588A DK388588A DK388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A DK 388588 A DK388588 A DK 388588A
Authority
DK
Denmark
Prior art keywords
propanamines
benzisoxazole
dimethoxy
substituted
preparation
Prior art date
Application number
DK388588A
Other languages
English (en)
Other versions
DK388588D0 (da
Inventor
Larry Davis
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK388588D0 publication Critical patent/DK388588D0/da
Publication of DK388588A publication Critical patent/DK388588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK388588A 1987-07-13 1988-07-12 N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse DK388588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,954 US4980365A (en) 1987-07-13 1987-07-13 N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents

Publications (2)

Publication Number Publication Date
DK388588D0 DK388588D0 (da) 1988-07-12
DK388588A true DK388588A (da) 1989-01-14

Family

ID=22110785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK388588A DK388588A (da) 1987-07-13 1988-07-12 N-substituerede-5,6-dimethoxy-1,2-benzisoxazol-3-propanaminer og hermed beslaegtede forbindelser, deres fremstilling og anvendelse

Country Status (5)

Country Link
US (1) US4980365A (da)
EP (1) EP0299349A2 (da)
JP (1) JPH0193578A (da)
DK (1) DK388588A (da)
PT (1) PT87968A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030639A (en) * 1987-07-13 1991-07-09 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
US5338857A (en) * 1989-08-04 1994-08-16 Mitsui Toatsu Chemicals Incorporated Aminoketone derivatives of 1,2-oxazole and use thereof
EP0414391B1 (en) * 1989-08-04 1995-03-15 MITSUI TOATSU CHEMICALS, Inc. Aminoketone derivatives and use thereof
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
WO1992017475A1 (en) * 1991-03-28 1992-10-15 Pfizer Inc. Heterocyclic-cyclic amine derivatives
KR950704252A (ko) * 1992-12-21 1995-11-17 우에하라 아키라 N-치환 이미다졸 유도체
ES2074966B1 (es) * 1994-02-11 1996-06-16 Vita Invest Sa Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
FR2735129B1 (fr) * 1995-06-07 1997-07-11 Adir Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1997040027A1 (en) * 1996-04-19 1997-10-30 Akzo Nobel N.V. Substituted benzylamines and their use for the treatment of depression
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
KR100542552B1 (ko) 2003-08-21 2006-01-11 삼성전자주식회사 인쇄회로기판, 및 이 인쇄회로기판을 갖는 화상기록장치
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CN101759693B (zh) * 2008-12-23 2011-09-14 江苏恩华药业股份有限公司 苯骈异恶唑哌啶衍生物及在制备镇痛、镇静药物中的应用
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH556129A (de) * 1973-03-09 1974-11-15 Bbc Brown Boveri & Cie Verfahren zur herstellung einer aus schichten bestehenden elektrischen schaltung.
JPS51136666A (en) * 1975-05-19 1976-11-26 Dainippon Pharmaceut Co Ltd Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives.
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles

Also Published As

Publication number Publication date
US4980365A (en) 1990-12-25
DK388588D0 (da) 1988-07-12
PT87968A (pt) 1989-06-30
EP0299349A2 (en) 1989-01-18
JPH0193578A (ja) 1989-04-12

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Legal Events

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ATS Application withdrawn