PT87968A - Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem

Info

Publication number
PT87968A
PT87968A PT87968A PT8796888A PT87968A PT 87968 A PT87968 A PT 87968A PT 87968 A PT87968 A PT 87968A PT 8796888 A PT8796888 A PT 8796888A PT 87968 A PT87968 A PT 87968A
Authority
PT
Portugal
Prior art keywords
propanamins
dimetoxy
benzimidazolo
substituted
contain
Prior art date
Application number
PT87968A
Other languages
English (en)
Inventor
Larry Davis
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT87968A publication Critical patent/PT87968A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT87968A 1987-07-13 1988-07-12 Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem PT87968A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,954 US4980365A (en) 1987-07-13 1987-07-13 N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents

Publications (1)

Publication Number Publication Date
PT87968A true PT87968A (pt) 1989-06-30

Family

ID=22110785

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87968A PT87968A (pt) 1987-07-13 1988-07-12 Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem

Country Status (5)

Country Link
US (1) US4980365A (pt)
EP (1) EP0299349A2 (pt)
JP (1) JPH0193578A (pt)
DK (1) DK388588A (pt)
PT (1) PT87968A (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030639A (en) * 1987-07-13 1991-07-09 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
FI96856C (fi) * 1989-08-04 1996-09-10 Mitsui Toatsu Chemicals Menetelmä terapeuttisesti käyttökelpoisten aminoketonijohdannaisten valmistamiseksi
US5338857A (en) * 1989-08-04 1994-08-16 Mitsui Toatsu Chemicals Incorporated Aminoketone derivatives of 1,2-oxazole and use thereof
PL171914B1 (pl) * 1991-03-28 1997-06-30 Eisai Co Ltd Sposób wytwarzania pochodnych aminy heterocyklicznej PL PL PL PL PL PL PL
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
AU5715494A (en) * 1992-12-21 1994-07-19 Taisho Pharmaceutical Co., Ltd. N-substituted indole derivative
ES2074966B1 (es) * 1994-02-11 1996-06-16 Vita Invest Sa Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
FR2735129B1 (fr) * 1995-06-07 1997-07-11 Adir Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DK0898566T3 (da) * 1996-04-19 2003-03-03 Akzo Nobel Nv Substituerede benzylaminer og anvendelse deraf til behandling af depression
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
KR100542552B1 (ko) 2003-08-21 2006-01-11 삼성전자주식회사 인쇄회로기판, 및 이 인쇄회로기판을 갖는 화상기록장치
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
CN101759693B (zh) * 2008-12-23 2011-09-14 江苏恩华药业股份有限公司 苯骈异恶唑哌啶衍生物及在制备镇痛、镇静药物中的应用
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH556129A (de) * 1973-03-09 1974-11-15 Bbc Brown Boveri & Cie Verfahren zur herstellung einer aus schichten bestehenden elektrischen schaltung.
JPS51136666A (en) * 1975-05-19 1976-11-26 Dainippon Pharmaceut Co Ltd Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives.
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

Also Published As

Publication number Publication date
EP0299349A2 (en) 1989-01-18
DK388588D0 (da) 1988-07-12
US4980365A (en) 1990-12-25
DK388588A (da) 1989-01-14
JPH0193578A (ja) 1989-04-12

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Legal Events

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FC3A Refusal

Effective date: 19941114