DK389080A - Fremgangsmaade til fremstilling af racemiske eller optisk aktive cephalosporin-analoge carbacephemforbindelser eller farmaceutisk accepable salte deraf - Google Patents

Fremgangsmaade til fremstilling af racemiske eller optisk aktive cephalosporin-analoge carbacephemforbindelser eller farmaceutisk accepable salte deraf

Info

Publication number
DK389080A
DK389080A DK389080A DK389080A DK389080A DK 389080 A DK389080 A DK 389080A DK 389080 A DK389080 A DK 389080A DK 389080 A DK389080 A DK 389080A DK 389080 A DK389080 A DK 389080A
Authority
DK
Denmark
Prior art keywords
pharmaceutical
procedure
optically active
preparing racemic
active cephalosporin
Prior art date
Application number
DK389080A
Other languages
English (en)
Inventor
T Hirata
T Ogasa
S Kobayashi
K Sato
C Urakawa
A Sato
Y Hashimoto
S Takasawa
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11672079A external-priority patent/JPS5640683A/ja
Priority claimed from JP13698779A external-priority patent/JPS5661378A/ja
Priority claimed from JP2203580A external-priority patent/JPS56118084A/ja
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of DK389080A publication Critical patent/DK389080A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
DK389080A 1979-09-13 1980-09-12 Fremgangsmaade til fremstilling af racemiske eller optisk aktive cephalosporin-analoge carbacephemforbindelser eller farmaceutisk accepable salte deraf DK389080A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11672079A JPS5640683A (en) 1979-09-13 1979-09-13 Cephalosporin analogue
JP13698779A JPS5661378A (en) 1979-10-25 1979-10-25 Optically active cephalosporin analog
JP2203580A JPS56118084A (en) 1980-02-23 1980-02-23 Optically active cephalosporin analogue

Publications (1)

Publication Number Publication Date
DK389080A true DK389080A (da) 1981-03-14

Family

ID=27283683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK389080A DK389080A (da) 1979-09-13 1980-09-12 Fremgangsmaade til fremstilling af racemiske eller optisk aktive cephalosporin-analoge carbacephemforbindelser eller farmaceutisk accepable salte deraf

Country Status (6)

Country Link
EP (1) EP0025602B1 (da)
CA (1) CA1178957A (da)
DE (1) DE3069832D1 (da)
DK (1) DK389080A (da)
ES (1) ES495035A0 (da)
NO (1) NO802713L (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
PH19170A (en) * 1981-03-30 1986-01-16 Squibb & Sons Inc 2 oxo-1-(substituted phosphorous)azetidines
EP0082501A1 (en) * 1981-12-18 1983-06-29 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound and a pharmaceutical composition containing the same
EP0112481A1 (en) * 1982-11-12 1984-07-04 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound
DE3803169A1 (de) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
US5099015A (en) * 1991-01-10 1992-03-24 Eli Lilly And Company Trifluoromethyl 1-carba(1-dethia)cephems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012383A (en) * 1975-01-02 1977-03-15 Bristol-Myers Company Δ2,3 -1,4-morpholine-2-carboxylic acids and derivatives thereof useful in preparation of antibacteria agents
US4089956A (en) * 1976-09-08 1978-05-16 Smithkline Corporation 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof
JPS54128591A (en) * 1978-03-25 1979-10-05 Kyowa Hakko Kogyo Co Ltd Cephalosporin analog

Also Published As

Publication number Publication date
DE3069832D1 (en) 1985-01-31
NO802713L (no) 1981-03-16
EP0025602A1 (en) 1981-03-25
ES8200689A1 (es) 1981-11-16
ES495035A0 (es) 1981-11-16
EP0025602B1 (en) 1984-12-19
CA1178957A (en) 1984-12-04

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment