DK3899027T3 - Identifikation af beslægtede par af ligander og en receptorer - Google Patents
Identifikation af beslægtede par af ligander og en receptorer Download PDFInfo
- Publication number
- DK3899027T3 DK3899027T3 DK19828270.9T DK19828270T DK3899027T3 DK 3899027 T3 DK3899027 T3 DK 3899027T3 DK 19828270 T DK19828270 T DK 19828270T DK 3899027 T3 DK3899027 T3 DK 3899027T3
- Authority
- DK
- Denmark
- Prior art keywords
- ligands
- receptors
- identification
- related pairs
- pairs
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/149—Modifications characterised by incorporating a coding sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/629—Detection means characterised by use of a special device being a microfluidic device
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18306741.2A EP3670667A1 (en) | 2018-12-19 | 2018-12-19 | Identification of cognate pairs of ligands and receptors |
| PCT/EP2019/086334 WO2020127754A1 (en) | 2018-12-19 | 2019-12-19 | Identification of cognate pairs of ligands and receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3899027T3 true DK3899027T3 (da) | 2023-05-01 |
Family
ID=65324139
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK23163171.4T DK4234712T3 (da) | 2018-12-19 | 2019-12-19 | Identifikation af kognitive par af ligander og receptorer |
| DK24195348.8T DK4495236T3 (da) | 2018-12-19 | 2019-12-19 | Identifikation af beslægtede par af ligander og receptorer |
| DK19828270.9T DK3899027T3 (da) | 2018-12-19 | 2019-12-19 | Identifikation af beslægtede par af ligander og en receptorer |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK23163171.4T DK4234712T3 (da) | 2018-12-19 | 2019-12-19 | Identifikation af kognitive par af ligander og receptorer |
| DK24195348.8T DK4495236T3 (da) | 2018-12-19 | 2019-12-19 | Identifikation af beslægtede par af ligander og receptorer |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220065849A1 (da) |
| EP (4) | EP3670667A1 (da) |
| DK (3) | DK4234712T3 (da) |
| LT (3) | LT4495236T (da) |
| WO (1) | WO2020127754A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3215070A1 (en) * | 2021-04-14 | 2022-10-20 | Joseph DE RUTTE | Nanoscale reaction chambers and methods of using the same |
| EP4490737A1 (en) * | 2022-03-08 | 2025-01-15 | 10X Genomics, Inc. | In situ code design methods for minimizing optical crowding |
| EP4592676A1 (en) * | 2024-01-29 | 2025-07-30 | Saber Bio SAS | Methods and systems for screening ligands and receptors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962271A (en) | 1996-01-03 | 1999-10-05 | Cloutech Laboratories, Inc. | Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end |
| JP2006507921A (ja) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
| EP2127736A1 (en) | 2003-04-10 | 2009-12-02 | The President and Fellows of Harvard College | Formation and control of fluidic species |
| JP2006349060A (ja) | 2005-06-16 | 2006-12-28 | Ntn Corp | ボールねじ |
| WO2008109176A2 (en) | 2007-03-07 | 2008-09-12 | President And Fellows Of Harvard College | Assays and other reactions involving droplets |
| WO2008130977A2 (en) | 2007-04-16 | 2008-10-30 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
| US9068181B2 (en) | 2008-05-23 | 2015-06-30 | The General Hospital Corporation | Microfluidic droplet encapsulation |
| US20110223314A1 (en) | 2010-03-10 | 2011-09-15 | Xiaoxiao Zhang | Efficient microencapsulation |
| DK2823060T3 (da) * | 2012-03-05 | 2018-05-28 | Adaptive Biotechnologies Corp | Bestemmelse af forbundne immunreceptorkæder fra hyppighedsafstemte underenheder |
| AU2014245806B2 (en) * | 2013-03-28 | 2019-10-31 | The University Of British Columbia | Microfluidic devices and methods for use thereof in multicellular assays of secretion |
| WO2017013170A1 (en) * | 2015-07-22 | 2017-01-26 | F. Hoffmann-La Roche Ag | Identification of antigen epitopes and immune sequences recognizing the antigens |
| MA44007A (fr) * | 2016-02-05 | 2018-12-19 | Denali Therapeutics Inc | Inhibiteurs du récepteur interagissant avec protéine kinase 1 |
| TWI758298B (zh) * | 2016-06-23 | 2022-03-21 | 國立研究開發法人理化學研究所 | 利用單步驟逆轉錄模板置換pcr之t細胞受體及b細胞受體多樣性解析系統 |
| JP6916309B2 (ja) * | 2017-03-13 | 2021-08-11 | ギガジェン,インコーポレイティッド | 単一細胞の大規模並行コンビナトリアル分析のためのシステム及び方法 |
-
2018
- 2018-12-19 EP EP18306741.2A patent/EP3670667A1/en not_active Withdrawn
-
2019
- 2019-12-19 EP EP23163171.4A patent/EP4234712B1/en active Active
- 2019-12-19 WO PCT/EP2019/086334 patent/WO2020127754A1/en not_active Ceased
- 2019-12-19 DK DK23163171.4T patent/DK4234712T3/da active
- 2019-12-19 DK DK24195348.8T patent/DK4495236T3/da active
- 2019-12-19 DK DK19828270.9T patent/DK3899027T3/da active
- 2019-12-19 EP EP19828270.9A patent/EP3899027B1/en active Active
- 2019-12-19 EP EP24195348.8A patent/EP4495236B1/en active Active
- 2019-12-19 LT LTEP24195348.8T patent/LT4495236T/lt unknown
- 2019-12-19 LT LTEP23163171.4T patent/LT4234712T/lt unknown
- 2019-12-19 US US17/416,287 patent/US20220065849A1/en active Pending
- 2019-12-19 LT LTEPPCT/EP2019/086334T patent/LT3899027T/lt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4234712A3 (en) | 2023-09-27 |
| EP3899027B1 (en) | 2023-03-22 |
| EP4234712B1 (en) | 2024-08-21 |
| EP3670667A1 (en) | 2020-06-24 |
| LT4234712T (lt) | 2025-01-10 |
| EP3899027A1 (en) | 2021-10-27 |
| EP4495236A3 (en) | 2025-02-26 |
| DK4495236T3 (da) | 2026-03-02 |
| EP4495236A2 (en) | 2025-01-22 |
| US20220065849A1 (en) | 2022-03-03 |
| EP4234712A2 (en) | 2023-08-30 |
| LT4495236T (lt) | 2026-04-10 |
| EP4495236B1 (en) | 2026-02-11 |
| WO2020127754A1 (en) | 2020-06-25 |
| DK4234712T3 (da) | 2024-10-28 |
| LT3899027T (lt) | 2023-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL283639A (en) | Kif18a inhibitors | |
| IL280298A (en) | Task completion using a blockchain network | |
| DK3775909T3 (da) | Midler og fremgangsmåder til glykoprofilering af et protein | |
| CA200054S (fr) | Bracelet | |
| EP3773320C0 (en) | RELEASEABLE PALATE EXPANSION DEVICES | |
| DK3806745T3 (da) | Anden læser | |
| DK3746424T3 (da) | Erbb/btk-inhibitorer | |
| DK3423451T3 (da) | Inhibitorer af wdr5-protein-proteinbinding | |
| HUE065501T2 (hu) | A KEAP1-NRF2 protein-protein kölcsönhatás inhibitorok | |
| EP3864235C0 (en) | UNDERLAYER | |
| EP3809912A4 (en) | WALLET | |
| DK3844162T3 (da) | Hæmmere af alfa-v-beta6-integrin | |
| EP3852571A4 (en) | JEWELRY DEVICE | |
| MA47203A (fr) | Inhibiteurs d'antiport à médiation par nhe | |
| IL281514A (en) | O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | |
| DK3899027T3 (da) | Identifikation af beslægtede par af ligander og en receptorer | |
| DK3452425T3 (da) | Anlæg og fremgangsmåde til fremstilling af et bindemiddel | |
| DK3824696T3 (da) | Belysningsindretning og en fremgangsmåde | |
| EP3898177C0 (en) | MOLD CONFIGURATION | |
| EP3446498A4 (en) | MICROPHONE PLACEMENT | |
| DK3649658T3 (da) | Fremgangsmåde til vedligeholdelse af en transformer og transformeranordning | |
| DK3856106T3 (da) | A garment | |
| DK3847391T3 (da) | Forbindelsesindretning og fremgangsmåde til fremstilling af en forbindelsesindretning | |
| DK3636975T3 (da) | Forsyningsledningsafslutningsanordning og fremgangsmåde til dannelse af en forsyningsledningsafslutningsanordning | |
| DK3895463T3 (da) | Sikret anvendelse og tilvejebringelse af en white-box-baseret klynge |