LT4495236T - Giminingų ligandų ir receptorių porų identifikavimas - Google Patents
Giminingų ligandų ir receptorių porų identifikavimasInfo
- Publication number
- LT4495236T LT4495236T LTEP24195348.8T LT24195348T LT4495236T LT 4495236 T LT4495236 T LT 4495236T LT 24195348 T LT24195348 T LT 24195348T LT 4495236 T LT4495236 T LT 4495236T
- Authority
- LT
- Lithuania
- Prior art keywords
- ligands
- receptors
- identification
- cognate pairs
- cognate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/149—Modifications characterised by incorporating a coding sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/629—Detection means characterised by use of a special device being a microfluidic device
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18306741.2A EP3670667A1 (en) | 2018-12-19 | 2018-12-19 | Identification of cognate pairs of ligands and receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT4495236T true LT4495236T (lt) | 2026-04-10 |
Family
ID=65324139
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP24195348.8T LT4495236T (lt) | 2018-12-19 | 2019-12-19 | Giminingų ligandų ir receptorių porų identifikavimas |
| LTEPPCT/EP2019/086334T LT3899027T (lt) | 2018-12-19 | 2019-12-19 | Ligandų ir receptorių giminingų porų identifikavimo būdas |
| LTEP23163171.4T LT4234712T (lt) | 2018-12-19 | 2019-12-19 | Giminingų ligandų ir receptorių porų identifikavimas |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/EP2019/086334T LT3899027T (lt) | 2018-12-19 | 2019-12-19 | Ligandų ir receptorių giminingų porų identifikavimo būdas |
| LTEP23163171.4T LT4234712T (lt) | 2018-12-19 | 2019-12-19 | Giminingų ligandų ir receptorių porų identifikavimas |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US12618832B2 (lt) |
| EP (5) | EP3670667A1 (lt) |
| DK (3) | DK4234712T3 (lt) |
| LT (3) | LT4495236T (lt) |
| WO (1) | WO2020127754A1 (lt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250264477A1 (en) * | 2021-04-14 | 2025-08-21 | Partillion Bioscience Corporation | Nanoscale reaction chambers and methods of using the same |
| WO2023172915A1 (en) * | 2022-03-08 | 2023-09-14 | 10X Genomics, Inc. | In situ code design methods for minimizing optical crowding |
| EP4592676A1 (en) * | 2024-01-29 | 2025-07-30 | Saber Bio SAS | Methods and systems for screening ligands and receptors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962271A (en) | 1996-01-03 | 1999-10-05 | Cloutech Laboratories, Inc. | Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end |
| US7201833B2 (en) * | 2001-06-04 | 2007-04-10 | Epocal Inc. | Integrated solid-phase hydrophilic matrix circuits and micro-arrays |
| JP2006507921A (ja) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
| CA2521862C (en) | 2003-04-10 | 2012-10-16 | President And Fellows Of Harvard College | Formation and control of fluidic species |
| JP2006349060A (ja) | 2005-06-16 | 2006-12-28 | Ntn Corp | ボールねじ |
| WO2008109176A2 (en) | 2007-03-07 | 2008-09-12 | President And Fellows Of Harvard College | Assays and other reactions involving droplets |
| EP2142279A2 (en) | 2007-04-16 | 2010-01-13 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
| US9068181B2 (en) | 2008-05-23 | 2015-06-30 | The General Hospital Corporation | Microfluidic droplet encapsulation |
| US20110223314A1 (en) | 2010-03-10 | 2011-09-15 | Xiaoxiao Zhang | Efficient microencapsulation |
| US10077478B2 (en) * | 2012-03-05 | 2018-09-18 | Adaptive Biotechnologies Corp. | Determining paired immune receptor chains from frequency matched subunits |
| KR102402451B1 (ko) * | 2013-03-28 | 2022-05-26 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 미세유동 장치 및 분비물의 다세포 검정법에서의 그의 사용 방법 |
| WO2017013170A1 (en) * | 2015-07-22 | 2017-01-26 | F. Hoffmann-La Roche Ag | Identification of antigen epitopes and immune sequences recognizing the antigens |
| US9815850B2 (en) * | 2016-02-05 | 2017-11-14 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| EP3486321A4 (en) * | 2016-06-23 | 2020-01-15 | Riken | SYSTEM FOR T CELL RECEPTOR AND B CELL RECEPTOR ANALYSIS USING ONE-STEP RT-PCR WITH MATRIX SWITCHING |
| AU2018235786B2 (en) * | 2017-03-13 | 2020-05-28 | Gigagen, Inc. | Systems and methods for massively parallel combinatorial analysis of single cells |
-
2018
- 2018-12-19 EP EP18306741.2A patent/EP3670667A1/en not_active Withdrawn
-
2019
- 2019-12-19 EP EP24195348.8A patent/EP4495236B1/en active Active
- 2019-12-19 EP EP26150530.9A patent/EP4752221A3/en active Pending
- 2019-12-19 LT LTEP24195348.8T patent/LT4495236T/lt unknown
- 2019-12-19 LT LTEPPCT/EP2019/086334T patent/LT3899027T/lt unknown
- 2019-12-19 US US17/416,287 patent/US12618832B2/en active Active
- 2019-12-19 LT LTEP23163171.4T patent/LT4234712T/lt unknown
- 2019-12-19 EP EP19828270.9A patent/EP3899027B1/en active Active
- 2019-12-19 DK DK23163171.4T patent/DK4234712T3/da active
- 2019-12-19 DK DK24195348.8T patent/DK4495236T3/da active
- 2019-12-19 DK DK19828270.9T patent/DK3899027T3/da active
- 2019-12-19 WO PCT/EP2019/086334 patent/WO2020127754A1/en not_active Ceased
- 2019-12-19 EP EP23163171.4A patent/EP4234712B1/en active Active
-
2026
- 2026-03-30 US US19/633,491 patent/US20260235585A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4752221A2 (en) | 2026-06-03 |
| EP3899027B1 (en) | 2023-03-22 |
| DK3899027T3 (da) | 2023-05-01 |
| EP3899027A1 (en) | 2021-10-27 |
| EP4752221A3 (en) | 2026-07-08 |
| WO2020127754A1 (en) | 2020-06-25 |
| US20260235585A1 (en) | 2026-08-13 |
| US12618832B2 (en) | 2026-05-05 |
| LT3899027T (lt) | 2023-07-10 |
| EP4234712A2 (en) | 2023-08-30 |
| EP3670667A1 (en) | 2020-06-24 |
| DK4495236T3 (da) | 2026-03-02 |
| LT4234712T (lt) | 2025-01-10 |
| DK4234712T3 (da) | 2024-10-28 |
| EP4495236B1 (en) | 2026-02-11 |
| EP4234712B1 (en) | 2024-08-21 |
| EP4495236A2 (en) | 2025-01-22 |
| EP4234712A3 (en) | 2023-09-27 |
| EP4495236A3 (en) | 2025-02-26 |
| US20220065849A1 (en) | 2022-03-03 |
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