DK3909584T5 - Pyrimidinforbindelse eller salt deraf - Google Patents

Pyrimidinforbindelse eller salt deraf Download PDF

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Publication number
DK3909584T5
DK3909584T5 DK20737875.3T DK20737875T DK3909584T5 DK 3909584 T5 DK3909584 T5 DK 3909584T5 DK 20737875 T DK20737875 T DK 20737875T DK 3909584 T5 DK3909584 T5 DK 3909584T5
Authority
DK
Denmark
Prior art keywords
pyrimide
salt
compound
pyrimide compound
Prior art date
Application number
DK20737875.3T
Other languages
English (en)
Other versions
DK3909584T3 (da
Inventor
Masayuki Nakamura
Takahiro Asai
Satoru Iguchi
Kei Oguchi
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK3909584T3 publication Critical patent/DK3909584T3/da
Publication of DK3909584T5 publication Critical patent/DK3909584T5/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK20737875.3T 2019-01-11 2020-01-10 Pyrimidinforbindelse eller salt deraf DK3909584T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019003403 2019-01-11
PCT/JP2020/000592 WO2020145374A1 (ja) 2019-01-11 2020-01-10 ピリミジン化合物又はその塩

Publications (2)

Publication Number Publication Date
DK3909584T3 DK3909584T3 (da) 2024-01-15
DK3909584T5 true DK3909584T5 (da) 2024-08-05

Family

ID=71520288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20737875.3T DK3909584T5 (da) 2019-01-11 2020-01-10 Pyrimidinforbindelse eller salt deraf

Country Status (20)

Country Link
US (1) US11078207B2 (da)
EP (1) EP3909584B1 (da)
JP (1) JP6783974B1 (da)
KR (1) KR102640463B1 (da)
CN (1) CN113271950B (da)
AU (1) AU2020206640B2 (da)
CA (1) CA3121722C (da)
DK (1) DK3909584T5 (da)
ES (1) ES2969151T3 (da)
FI (1) FI3909584T3 (da)
HU (1) HUE065967T2 (da)
MA (1) MA54702A (da)
MX (1) MX2021008252A (da)
MY (1) MY206124A (da)
PH (1) PH12021551630A1 (da)
PL (1) PL3909584T3 (da)
PT (1) PT3909584T (da)
SG (1) SG11202107528PA (da)
TW (1) TWI783204B (da)
WO (1) WO2020145374A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230285397A1 (en) * 2020-07-15 2023-09-14 Taiho Pharmaceutical Co., Ltd. Egfr inhibitor
EP4183395A4 (en) * 2020-07-15 2024-07-24 Taiho Pharmaceutical Co., Ltd. PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT
US12492208B2 (en) 2020-07-15 2025-12-09 Taiho Pharmaceutical Co., Ltd. Crystal of pyrimidine compound
TWI911331B (zh) * 2020-11-20 2026-01-11 日商大鵬藥品工業股份有限公司 以縮合嘧啶化合物作為有效成分之腦移行性腫瘤治療劑
JP2024520461A (ja) * 2021-05-24 2024-05-24 大鵬薬品工業株式会社 Egfr及び/又はher2に異常を有するがんを有する対象の治療方法
WO2024173565A2 (en) * 2023-02-14 2024-08-22 New York University Human synthetic antibodies targeting human epidermal growth factor receptor 2 (her2) mutants

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8426428B2 (en) * 2008-12-05 2013-04-23 Principia Biopharma, Inc. EGFR kinase knockdown via electrophilically enhanced inhibitors
TW201336847A (zh) * 2012-02-07 2013-09-16 Taiho Pharmaceutical Co Ltd 喹啉基吡咯并嘧啶化合物或其鹽
MX360498B (es) * 2013-08-12 2018-11-05 Taiho Pharmaceutical Co Ltd Compuesto novedoso de pirimidina fusionada o sal del mismo.
JP6141568B1 (ja) 2015-09-01 2017-06-07 大鵬薬品工業株式会社 新規なピラゾロ[3,4−d]ピリミジン化合物又はその塩
TWI623316B (zh) * 2015-12-22 2018-05-11 Taiho Pharmaceutical Co Ltd Antitumor effect enhancer derived from pyrrolopyrimidine compound
CA3015484C (en) 2016-02-23 2022-11-08 Taiho Pharmaceutical Co., Ltd. Novel condensed pyrimidine compound or salt thereof
WO2017184775A1 (en) * 2016-04-19 2017-10-26 The Regents Of The University Of California Erbb inhibitors and uses thereof
JP6779835B2 (ja) 2017-06-15 2020-11-04 株式会社日立製作所 監視制御システム、監視制御装置及び監視制御方法

Also Published As

Publication number Publication date
JPWO2020145374A1 (ja) 2021-02-18
SG11202107528PA (en) 2021-08-30
BR112021013460A2 (pt) 2021-09-21
FI3909584T3 (fi) 2024-01-09
JP6783974B1 (ja) 2020-11-11
PT3909584T (pt) 2024-01-12
WO2020145374A1 (ja) 2020-07-16
EP3909584A4 (en) 2022-09-28
TWI783204B (zh) 2022-11-11
CN113271950A (zh) 2021-08-17
MX2021008252A (es) 2021-08-16
PH12021551630A1 (en) 2022-06-06
CN113271950B (zh) 2024-04-30
US11078207B2 (en) 2021-08-03
ES2969151T3 (es) 2024-05-16
EP3909584A1 (en) 2021-11-17
AU2020206640A1 (en) 2021-08-12
KR20210102373A (ko) 2021-08-19
MA54702A (fr) 2021-11-17
KR102640463B1 (ko) 2024-02-23
HUE065967T2 (hu) 2024-07-28
EP3909584B1 (en) 2023-12-13
CA3121722C (en) 2024-01-16
PL3909584T3 (pl) 2024-03-25
DK3909584T3 (da) 2024-01-15
CA3121722A1 (en) 2020-07-16
AU2020206640B2 (en) 2022-09-08
US20210024530A1 (en) 2021-01-28
MY206124A (en) 2024-11-30
TW202043230A (zh) 2020-12-01

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