DK392686A - Kulsyremonoesterafledte n- og/eller o-acylater af desferrioxamin b og salte deraf - Google Patents
Kulsyremonoesterafledte n- og/eller o-acylater af desferrioxamin b og salte deraf Download PDFInfo
- Publication number
- DK392686A DK392686A DK392686A DK392686A DK392686A DK 392686 A DK392686 A DK 392686A DK 392686 A DK392686 A DK 392686A DK 392686 A DK392686 A DK 392686A DK 392686 A DK392686 A DK 392686A
- Authority
- DK
- Denmark
- Prior art keywords
- desferrioxamine
- pct
- iii
- iron
- carbonic acid
- Prior art date
Links
- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 title abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title 1
- 229910052799 carbon Inorganic materials 0.000 title 1
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001727 carbonic acid monoesters Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Carbon And Carbon Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH601584 | 1984-12-19 | ||
| CH45485 | 1985-02-01 | ||
| PCT/CH1985/000175 WO1986003747A1 (fr) | 1984-12-19 | 1985-12-13 | Nouveaux esters d'acide carbonique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK392686D0 DK392686D0 (da) | 1986-08-18 |
| DK392686A true DK392686A (da) | 1986-08-18 |
Family
ID=25684627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK392686A DK392686A (da) | 1984-12-19 | 1986-08-18 | Kulsyremonoesterafledte n- og/eller o-acylater af desferrioxamin b og salte deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4764523A (da) |
| EP (1) | EP0207097B1 (da) |
| KR (1) | KR870700065A (da) |
| AT (1) | ATE55375T1 (da) |
| AU (1) | AU596791B2 (da) |
| CA (1) | CA1287358C (da) |
| DE (1) | DE3579164D1 (da) |
| DK (1) | DK392686A (da) |
| ES (1) | ES8705361A1 (da) |
| PH (1) | PH26897A (da) |
| WO (1) | WO1986003747A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4940811A (en) * | 1986-12-09 | 1990-07-10 | Ciba-Geigy Corporation | N,N-disubstituted ureas and processes for their manufacture |
| MX12394A (es) * | 1987-07-23 | 1993-12-01 | Ciba Geigy Ag | Procedimiento par la obtencion de carbamatos de polietilenglicol. |
| ES2052771T3 (es) * | 1987-07-23 | 1994-07-16 | Ciba Geigy Ag | Procedimiento para la n-acilacion selectiva de derivados del acido amino-hidroxamico y los productos de partida empleados en el mismo. |
| US5021567A (en) * | 1987-09-24 | 1991-06-04 | Abbott Laboratories | 8-hydroxyquinoline chelating agents |
| DE58901673D1 (de) * | 1988-06-08 | 1992-07-23 | Ciba Geigy Ag | Carbamoylierte hydroxamsaeurederivate und verfahren zu ihrer herstellung. |
| IL98680A0 (en) * | 1991-06-30 | 1992-07-15 | Yeda Res & Dev | Hydroxamate derivatives and pharmaceutical compositions containing them |
| US5254724A (en) * | 1991-10-30 | 1993-10-19 | University Of Florida Research Foundation, Inc. | Method for synthesis of desferrioxamine B, analogs and homologs thereof |
| FI960803L (fi) * | 1993-08-23 | 1996-04-22 | Immunex Corp | TNF-alfa-sekreetion inhibiittoreita |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3634407A (en) * | 1969-06-19 | 1972-01-11 | Ciba Geigy Corp | Heavy metal complexes of trihydroxamic acids |
| US4612122A (en) * | 1981-06-29 | 1986-09-16 | Clara Ambrus | Removing heavy metal ions from blood |
| US4419365A (en) * | 1981-12-21 | 1983-12-06 | Ciba-Geigy Corporation | Method of treating Alzheimer's disease |
| US4671901A (en) * | 1984-01-26 | 1987-06-09 | Oral-D | Orally effective ion chelators |
-
1985
- 1985-12-13 WO PCT/CH1985/000175 patent/WO1986003747A1/de not_active Ceased
- 1985-12-13 AU AU51921/86A patent/AU596791B2/en not_active Ceased
- 1985-12-13 US US06/905,379 patent/US4764523A/en not_active Expired - Fee Related
- 1985-12-13 AT AT85906030T patent/ATE55375T1/de active
- 1985-12-13 DE DE8585906030T patent/DE3579164D1/de not_active Expired - Lifetime
- 1985-12-13 EP EP85906030A patent/EP0207097B1/de not_active Expired - Lifetime
- 1985-12-13 KR KR1019860700578A patent/KR870700065A/ko not_active Ceased
- 1985-12-18 CA CA000497985A patent/CA1287358C/en not_active Expired - Lifetime
- 1985-12-19 ES ES550174A patent/ES8705361A1/es not_active Expired
- 1985-12-19 PH PH33221A patent/PH26897A/en unknown
-
1986
- 1986-08-18 DK DK392686A patent/DK392686A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK392686D0 (da) | 1986-08-18 |
| ES8705361A1 (es) | 1987-05-01 |
| KR870700065A (ko) | 1987-02-28 |
| US4764523A (en) | 1988-08-16 |
| CA1287358C (en) | 1991-08-06 |
| DE3579164D1 (de) | 1990-09-13 |
| WO1986003747A1 (fr) | 1986-07-03 |
| EP0207097B1 (de) | 1990-08-08 |
| PH26897A (en) | 1992-12-03 |
| AU5192186A (en) | 1986-07-22 |
| ES550174A0 (es) | 1987-05-01 |
| EP0207097A1 (de) | 1987-01-07 |
| ATE55375T1 (de) | 1990-08-15 |
| AU596791B2 (en) | 1990-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment | ||
| AHB | Application shelved due to non-payment |