DK3976604T3 - 1,3,4-oxadiazol-derivatforbindelser som histondeacetylase 6-hæmmer og den farmaceutiske sammensætning, der omfatter den samme - Google Patents

1,3,4-oxadiazol-derivatforbindelser som histondeacetylase 6-hæmmer og den farmaceutiske sammensætning, der omfatter den samme

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Publication number
DK3976604T3
DK3976604T3 DK20814548.2T DK20814548T DK3976604T3 DK 3976604 T3 DK3976604 T3 DK 3976604T3 DK 20814548 T DK20814548 T DK 20814548T DK 3976604 T3 DK3976604 T3 DK 3976604T3
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DK
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Prior art keywords
inhibitors
pharmaceutical composition
same
derivative compounds
oxadiazole derivative
Prior art date
Application number
DK20814548.2T
Other languages
English (en)
Inventor
Changsik Lee
Jung Taek Oh
Hokeun Yun
Hyeseung Song
Hyunjin Michael Kim
Original Assignee
Chong Kun Dang Pharmaceutical Corp
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Publication date
Application filed by Chong Kun Dang Pharmaceutical Corp filed Critical Chong Kun Dang Pharmaceutical Corp
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Publication of DK3976604T3 publication Critical patent/DK3976604T3/da

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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DK20814548.2T 2019-05-31 2020-05-29 1,3,4-oxadiazol-derivatforbindelser som histondeacetylase 6-hæmmer og den farmaceutiske sammensætning, der omfatter den samme DK3976604T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20190064665 2019-05-31
PCT/IB2020/055109 WO2020240492A1 (en) 2019-05-31 2020-05-29 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same

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DK3976604T3 true DK3976604T3 (da) 2026-03-30

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DK20814548.2T DK3976604T3 (da) 2019-05-31 2020-05-29 1,3,4-oxadiazol-derivatforbindelser som histondeacetylase 6-hæmmer og den farmaceutiske sammensætning, der omfatter den samme

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Country Link
US (1) US20230092890A1 (da)
EP (1) EP3976604B1 (da)
JP (1) JP7301171B2 (da)
KR (1) KR102476818B1 (da)
CN (1) CN113924296B (da)
AU (1) AU2020284167B2 (da)
BR (1) BR112021023770A2 (da)
CA (1) CA3139026A1 (da)
DK (1) DK3976604T3 (da)
FI (1) FI3976604T3 (da)
MX (1) MX2021014372A (da)
PH (1) PH12021552930A1 (da)
TW (1) TWI748492B (da)
WO (1) WO2020240492A1 (da)

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WO2018165520A1 (en) 2017-03-10 2018-09-13 Vps-3, Inc. Metalloenzyme inhibitor compounds
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