DK40385A - Antitumor-farmaceutiske praeparater og fremgangsmaader til behandling af tumorer under anvendelse af (alfa,omega-bis-(disubstitueret phosphino)hydrocarbon)diguld(i)-,diguld(iii)-, disoelv(i)- og dikobber(i)-derivater - Google Patents

Antitumor-farmaceutiske praeparater og fremgangsmaader til behandling af tumorer under anvendelse af (alfa,omega-bis-(disubstitueret phosphino)hydrocarbon)diguld(i)-,diguld(iii)-, disoelv(i)- og dikobber(i)-derivater Download PDF

Info

Publication number: DK40385A
Authority: DK; Denmark
Prior art keywords: diguld; omega; bis; hydrocarbon; iii
Prior art date: 1984-02-01

Application number

DK40385A

Other languages

English (en)

Other versions

DK40385D0 (da

Inventor

David Taylor Hill

Randall Keith Johnson

Christopher Kevin Mirabelli

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-02-01

Filing date

1985-01-29

Publication date

1985-08-02

1985-01-29 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1985-01-29 Publication of DK40385D0 publication Critical patent/DK40385D0/da

1985-08-02 Publication of DK40385A publication Critical patent/DK40385A/da

Links

239000004215 Carbon black (E152) Substances 0.000 title abstract 2
206010028980 Neoplasm Diseases 0.000 title abstract 2
229930195733 hydrocarbon Natural products 0.000 title abstract 2
150000002430 hydrocarbons Chemical class 0.000 title abstract 2
FVZVCSNXTFCBQU-UHFFFAOYSA-N phosphanyl Chemical class [PH2] FVZVCSNXTFCBQU-UHFFFAOYSA-N 0.000 title abstract 2
230000000259 anti-tumor effect Effects 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000011282 treatment Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
210000004881 tumor cell Anatomy 0.000 abstract 1
230000004565 tumor cell growth Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK40385A 1984-02-01 1985-01-29 Antitumor-farmaceutiske praeparater og fremgangsmaader til behandling af tumorer under anvendelse af (alfa,omega-bis-(disubstitueret phosphino)hydrocarbon)diguld(i)-,diguld(iii)-, disoelv(i)- og dikobber(i)-derivater DK40385A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US57565084A	1984-02-01	1984-02-01

Publications (2)

Publication Number	Publication Date
DK40385D0 DK40385D0 (da)	1985-01-29
DK40385A true DK40385A (da)	1985-08-02

Family

ID=24301170

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK40385A DK40385A (da)	1984-02-01	1985-01-29	Antitumor-farmaceutiske praeparater og fremgangsmaader til behandling af tumorer under anvendelse af (alfa,omega-bis-(disubstitueret phosphino)hydrocarbon)diguld(i)-,diguld(iii)-, disoelv(i)- og dikobber(i)-derivater

Country Status (9)

Country	Link
EP (1)	EP0151046B1 (da)
JP (1)	JPS60188322A (da)
AT (1)	ATE43967T1 (da)
AU (1)	AU572949B2 (da)
CA (1)	CA1238854A (da)
DE (1)	DE3570981D1 (da)
DK (1)	DK40385A (da)
IE (1)	IE850226L (da)
ZA (1)	ZA85755B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH21350A (en) *	1984-06-04	1987-10-13	Smithkline Beckman Corp	Tumor cell growth imhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes
US5037812A (en) *	1985-04-02	1991-08-06	Smithkline Beckman Corporation	Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes
DK166686A (da) *	1985-04-16	1986-10-17	Smithkline Beckman Corp	Phosphinforbindelser, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser
US4716230A (en) *	1985-04-16	1987-12-29	Smithkline Beckman Corporation	Certain bis(di-2 or 4-pyridyl-phosphino) alkanes #10 having anti-tumor properties
US4902675A (en) *	1985-05-16	1990-02-20	Smithkline Beckman Corporation	"2-pyridyl and 4-pyridyl phosphine gold (I) anti tumor complexes"
EP0202854A3 (en) *	1985-05-20	1988-01-13	Smithkline Beecham Corporation	Phosphine gold compounds
US4698422A (en) *	1985-05-20	1987-10-06	Smithkline Beckman Corporation	Triphos and tetraphos gold compounds and ligands
NL8502929A (nl) *	1985-10-25	1987-05-18	Tno	Groep viii-overgangsmetaal-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijke groep viii-overgangsmetaal-complex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
US4758589A (en) *	1985-12-23	1988-07-19	Smithkline Beckman Corporation	Tetraphosphine-coordinated gold(I) complexes
US4764509A (en) *	1986-02-21	1988-08-16	Smithkline Beckman Corporation	Pharmaceutical compositions containing di-gold phosphine
AU1059395A (en) *	1993-11-24	1995-06-13	Luminis Pty Limited	Triorganophosphinegold (i) thionucleobases with anti-tumor activity
AU2001255125A1 (en)	2000-04-10	2001-10-23	National University Of Singapore	Gold complexes
WO2001077121A1 (en) *	2000-04-10	2001-10-18	National University Of Singapore	Gold complexes
DE10300097A1 (de) *	2003-01-07	2004-07-22	Bayer Ag	Kupfer-Komplexe und ihre Verwendung
WO2009074305A1 (de) *	2007-12-13	2009-06-18	Biosphings Ag	Gold-xanthogenate und diese enthaltende arzneimittel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3661959A (en) *	1970-07-30	1972-05-09	Du Pont	Method of making organogold chloride complexes
US3676554A (en) *	1970-10-30	1972-07-11	Smith Kline French Lab	Anti-arthritic compositions comprising phosphine or phosphite gold halide complexes and methods of producing anti-arthritic activity
PH21350A (en) *	1984-06-04	1987-10-13	Smithkline Beckman Corp	Tumor cell growth imhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes

1985
- 1985-01-07 CA CA000471598A patent/CA1238854A/en not_active Expired
- 1985-01-29 AU AU38126/85A patent/AU572949B2/en not_active Ceased
- 1985-01-29 DK DK40385A patent/DK40385A/da not_active Application Discontinuation
- 1985-01-31 EP EP85300681A patent/EP0151046B1/en not_active Expired
- 1985-01-31 DE DE8585300681T patent/DE3570981D1/de not_active Expired
- 1985-01-31 IE IE850226A patent/IE850226L/xx unknown
- 1985-01-31 AT AT85300681T patent/ATE43967T1/de not_active IP Right Cessation
- 1985-01-31 ZA ZA85755A patent/ZA85755B/xx unknown
- 1985-02-01 JP JP60019181A patent/JPS60188322A/ja active Pending

Also Published As

Publication number	Publication date
IE850226L (en)	1985-08-01
ATE43967T1 (de)	1989-06-15
EP0151046A2 (en)	1985-08-07
DE3570981D1 (en)	1989-07-20
CA1238854A (en)	1988-07-05
ZA85755B (en)	1986-05-28
EP0151046B1 (en)	1989-06-14
AU572949B2 (en)	1988-05-19
EP0151046A3 (en)	1985-08-21
DK40385D0 (da)	1985-01-29
AU3812685A (en)	1985-08-29
JPS60188322A (ja)	1985-09-25

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Legal Events

Date	Code	Title	Description
1991-09-23	AHB	Application shelved due to non-payment