DK406589A - Middel til behandling af maligne tumorer, indeholdende 8-chloradenosin-3',5'-cyclisk phosphat, 8-aminoacenosin-3',5'-cyclisk phosphat - Google Patents

Middel til behandling af maligne tumorer, indeholdende 8-chloradenosin-3',5'-cyclisk phosphat, 8-aminoacenosin-3',5'-cyclisk phosphat

Info

Publication number
DK406589A
DK406589A DK406589A DK406589A DK406589A DK 406589 A DK406589 A DK 406589A DK 406589 A DK406589 A DK 406589A DK 406589 A DK406589 A DK 406589A DK 406589 A DK406589 A DK 406589A
Authority
DK
Denmark
Prior art keywords
cyclic phosphate
chloradenosin
aminoacenosin
tumor treatment
treatment containing
Prior art date
Application number
DK406589A
Other languages
Danish (da)
English (en)
Other versions
DK406589D0 (da
Inventor
K Robins Roland
Ganapathi R Revankar
Yu-An Chang
Original Assignee
Nucleic Acid Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/136,407 external-priority patent/US4861873A/en
Application filed by Nucleic Acid Research Inst filed Critical Nucleic Acid Research Inst
Publication of DK406589D0 publication Critical patent/DK406589D0/da
Publication of DK406589A publication Critical patent/DK406589A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK406589A 1987-12-21 1989-08-18 Middel til behandling af maligne tumorer, indeholdende 8-chloradenosin-3',5'-cyclisk phosphat, 8-aminoacenosin-3',5'-cyclisk phosphat DK406589A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/136,407 US4861873A (en) 1987-12-21 1987-12-21 8-Chloroadenosine 3', 5'-cyclic monophosphate preparations
US18007088A 1988-04-11 1988-04-11
PCT/US1988/001217 WO1989005648A1 (en) 1987-12-21 1988-04-20 Treatment of malignant tumors with 8-chloroadenosine 3',5'-cyclic phosphate, 8-aminoadenosine 3',5'-cyclic phosphate and preparation thereof

Publications (2)

Publication Number Publication Date
DK406589D0 DK406589D0 (da) 1989-08-18
DK406589A true DK406589A (da) 1989-10-12

Family

ID=26834271

Family Applications (1)

Application Number Title Priority Date Filing Date
DK406589A DK406589A (da) 1987-12-21 1989-08-18 Middel til behandling af maligne tumorer, indeholdende 8-chloradenosin-3',5'-cyclisk phosphat, 8-aminoacenosin-3',5'-cyclisk phosphat

Country Status (10)

Country Link
EP (2) EP0346400A4 (es)
JP (1) JPH02502911A (es)
KR (1) KR900700107A (es)
AU (2) AU1933588A (es)
CA (1) CA1326849C (es)
DK (1) DK406589A (es)
ES (1) ES2019713A6 (es)
MX (1) MX168619B (es)
NZ (1) NZ224307A (es)
WO (2) WO1989005647A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1335572C (en) * 1988-05-23 1995-05-16 Yoon Sang Cho-Chung Derivatives of cyclic amp as treatment for cancer
US4908441A (en) * 1988-07-19 1990-03-13 Warner-Lambert Company Deoxyadenosine compounds and methods of making and using the same
WO1991019728A1 (en) * 1990-06-15 1991-12-26 Nippon Shinyaku Co., Ltd. Nucleotide derivative
CN1037575C (zh) * 1993-10-15 1998-03-04 北京市肿瘤防治研究所 8-氯腺苷制备抗肿瘤药物
GB201820685D0 (en) * 2018-12-19 2019-01-30 NuCana plc Synthesis of 8-chloroadenosine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1336441A (en) * 1969-10-10 1973-11-07 Anvar Derivatives of cyclo adenosine-3,5-phosphoric acid and their preparation
US3849553A (en) * 1973-09-04 1974-11-19 Nelson Res & Dev Cyclic nucleotide therapeutic preparation
US4369181A (en) * 1981-08-05 1983-01-18 Sri International Process for treating proliferative skin diseases using certain 6,8-substituted ribofuranosylpurine-3',5'-cyclic phosphates

Also Published As

Publication number Publication date
WO1989005648A1 (en) 1989-06-29
WO1989005647A1 (en) 1989-06-29
CA1326849C (en) 1994-02-08
NZ224307A (en) 1990-03-27
KR900700107A (ko) 1990-08-11
EP0499291A1 (en) 1992-08-19
DK406589D0 (da) 1989-08-18
ES2019713A6 (es) 1991-07-01
AU1933588A (en) 1989-07-19
MX168619B (es) 1993-06-01
JPH02502911A (ja) 1990-09-13
EP0346400A4 (en) 1990-11-28
EP0346400A1 (en) 1989-12-20
AU1932888A (en) 1989-07-19

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